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Abdominal Abscess clinical trials

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NCT ID: NCT02688244 Recruiting - Infection Clinical Trials

Irrigation Versus Suction in Complicated Acute Appendicitis

ISAAC
Start date: November 2015
Phase: N/A
Study type: Interventional

This study evaluates the intraabdominal abscess rate after laparoscopic appendectomy in complicated acute appendicitis performing irrigation of the abdominal cavity or only suction without lavage.

NCT ID: NCT01657565 Completed - Wound Infection Clinical Trials

Appendectomy in Children Performed by Residents in the Era of Laparoscopic Surgery

Start date: January 2006
Phase: N/A
Study type: Observational

Introduction: An increasing proportion of childhood appendicitis is treated with laparoscopic appendectomy (LA). The investigators wanted to elucidate the outcome of childhood appendicitis treated primarily by residents in a university hospital. Material and methods: All children (age<16 years) treated surgically with appendectomy in our department between January 2006 and January 2011 were retrospectively identified. Readmission, reoperation or postoperative length of stay (LOS) exceeding five days were considered as non-satisfactory outcomes.

NCT ID: NCT01597336 Completed - Abdominal Abscess Clinical Trials

Treatment of Abdominal Abscesses With or Without Fibrinolysis

Start date: June 2009
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the utility of fibrinolysis when draining an abdominal abscess as defined by length of stay after drainage.

NCT ID: NCT01576679 Suspended - Clinical trials for Intra-abdominal Abscess

Safety and Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-Abdominal Collections in Children - A Prospective Study

Start date: March 2012
Phase: Phase 3
Study type: Interventional

The objective of this study is to establish the efficacy of tPA when used in pediatric intra-abdominal abscesses immediately after percutaneous drainage, irrespective of the ultrasound appearance or consistency of the drained fluid.

NCT ID: NCT01568853 Completed - Severe Sepsis Clinical Trials

A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis

Start date: November 2011
Phase: N/A
Study type: Interventional

The role of complement system in bridging innate and adaptive immunity has been confirmed in various invasive pathogens. The aim of this study is to investigate the alteration of complement C3 in patients with severe abdominal sepsis and evaluate the role of complement C3 depletion in prognosis of such patients. The relationship between complement C3 depletion and adaptive immunity is studied meanwhile.

NCT ID: NCT01458353 Not yet recruiting - Wound Infection Clinical Trials

Microbiological Spectrum of the Intraperitoneal Surface After Elective Right-sided Colon Cancer

Start date: November 2011
Phase: Phase 3
Study type: Interventional

Despite performing colonic surgery with strict asepsia measures, minimizing the contact of the colon lumen with the peritoneum, some contamination is nearly impossible to avoid. In stapled anastomosis, the hole opened in the colon is minimum, just the necessary for introducing the parts of the mechanical devices. In handsewn anastomosis, the colonic lumen is more exposed to the peritoneum, despite the colonic occlusion with clamps meanwhile the suture is performed. Hypothesis: After stapled anastomoses, the peritoneal contamination should be lower than after handsewn ones.

NCT ID: NCT01283815 Completed - Appendicitis Clinical Trials

Laparoscopic Management of Periappendicular Abscess

Start date: January 2011
Phase: Phase 2
Study type: Interventional

According to retrospective studies the conservative management of periappendicular abscess is associated with decreased complication and re-operation rate compared with open appendectomy. Large abscesses require percutaneous drainage. Sometimes percutaneous drainage is not possible because of anatomical position of the abscess and surgical treatment is needed. The purpose of this study is evaluate whether laparoscopic appendectomy is suitable for the first-line treatment in patients with periappendicular abscess. The hypothesis of the study is that laparoscopic management of periappendicular abscess is suitable for the first-line treatment and it does not increase time of hospitalization or complication rate compared with conservative management.

NCT ID: NCT01110382 Terminated - Infection Clinical Trials

A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections

Start date: December 2010
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the safety and tolerability of doripenem compared with meropenem in children hospitalized with complicated intra-abdominal infections.

NCT ID: NCT01096511 Completed - Clinical trials for Abscess, Intra-Abdominal

Moxifloxacin i.v. in the Treatment of Complicated Intra-Abdominal Infection (cIAI)

Start date: December 2009
Phase: N/A
Study type: Observational

This study is a local, prospective, open-label, company-sponsored, non interventional, multi-center study. Patients documented must suffer from a cIAI and take at least one dose of Moxifloxacin infusion.The primary objective is to define the types of cIAI infections that require Moxifloxacin i.v. therapy in China.

NCT ID: NCT00931554 Completed - Pancreatic Fistula Clinical Trials

Randomized Trial of Early Versus Standard Drainage Removal After Pancreatic Resections

Start date: March 2007
Phase: N/A
Study type: Interventional

Despite a substantial decrease in postoperative mortality, morbidity after pancreatic resections is still high, even at high-volume centers. It has been recently suggested that early removal of postoperative drainages is associated to a decreased rate of intra-abdominal complications, with particular regard to pancreatic fistula. Furthermore, our research group demonstrated that measuring amylase value in drainages (AVD) on postoperative day 1 plays a cardinal role in predicting the developement of abdominal complications, including pancreatic fistula. In particular, patients with an AVD lower than 5000 IU/L in postoperative day 1 were considered at low risk of fistula. Therefore, the investigators designed a randomized prospective trial on early (postoperative day 3) versus standard (postoperative day 5) drainages removal after pancreatic resections in patients at low risk of developing pancreatic fistula (AVD < 5000 IU/L in postoperative day 1) to test whether drainages "per se" influence postoperative complication rates and to eventually validate a fast-track policy in pancreatic resections.