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Vomiting clinical trials

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NCT ID: NCT00272285 Completed - Nausea Clinical Trials

A Study of Ramosetron Plus DX, Dexamethasone, Compared to Granisetron Plus DX for the Prevention of Vomiting and Nausea

Start date: January 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of ramosetron plus dexamethasone injection with granisetron plus dexamethasone injection for the prevention of chemotherapy-induced vomiting and nausea.

NCT ID: NCT00268125 Completed - Breast Neoplasms Clinical Trials

Phase 3 Study of Acupression's Bracelets in Nausea and Vomiting Induced by FEC100 Chemotherapy's Sort.

Start date: February 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate a betterment of the digestive symptomatology by the anti-emetic acupression's bracelets's use associated with hygiene and dietetic advices.

NCT ID: NCT00250744 Completed - Cancer Clinical Trials

Comparison of Aprepitant Versus Gabapentin in the Prevention of Delayed Nausea and Vomiting

Start date: December 2004
Phase: Phase 2
Study type: Interventional

1. To compare the effectiveness of gabapentin (titrated to300mg TID days -2 to 5) with aprepitant (125mg on day 1 and 80mg on days 2 and 3) in the control of delayed nausea and vomiting associated with level 3, 4 or 5 emetogenic chemotherapy in patients who experienced delayed nausea and/or vomiting during their first cycle of chemotherapy. 2. To evaluate and compare the safety profile associated with each anti-emetic regimen. 3. To assess subject satisfaction with anti-emetic therapy.

NCT ID: NCT00248547 Completed - Cancer Clinical Trials

Aprepitant in Preventing Nausea and Vomiting in Patients Who Are Undergoing a Stem Cell Transplant

Start date: May 2004
Phase: N/A
Study type: Interventional

RATIONALE: Antiemetic drugs, such as aprepitant, ondansetron, and dexamethasone, may help lessen or prevent nausea and vomiting in patients undergoing a stem cell transplant. PURPOSE: This randomized clinical trial is studying aprepitant, ondansetron, and dexamethasone to see how well they work compared to placebo, ondansetron, and dexamethasone in preventing nausea and vomiting in patients who are undergoing a stem cell transplant.

NCT ID: NCT00231777 Completed - Clinical trials for Post-Operative Nausea and Vomiting

A Study to Examine the Safety and Tolerability of MK0517 for the Prevention of Post-Operative Nausea and Vomiting (0517-015)

Start date: July 2005
Phase: Phase 3
Study type: Interventional

A new intravenous medication is being tested for the prevention of the nausea and vomiting that occurs after surgery. This new medication is being compared to another intravenous medication that is already available to patients for this indication.

NCT ID: NCT00231478 Completed - Clinical trials for Post-Operative Nausea and Vomiting

A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy

Start date: April 2007
Phase: Phase 4
Study type: Interventional

This 2 arm study will evaluate the efficacy and safety of a single intravenous injection of Kytril in preventing postoperative nausea and vomiting (PONV) in children. Patients will be randomized to receive a single dose of either 20 micrograms or 40 micrograms Kytril intravenously (iv) 15 minutes prior to the end of surgery with general anesthesia for tonsillectomy or adenotonsillectomy. The anticipated time on study treatment is <3 months, and the planned sample size was 170 patients.

NCT ID: NCT00225238 Completed - Nausea Clinical Trials

The Effects of Nexium on the Side Effects Associated With a Colonoscopy Prep

Start date: December 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to ascertain if the use of Nexium for 7 days prior to taking a colon prep for a colonoscopy will decrease the side effects that are associated with the colon preparation

NCT ID: NCT00220688 Completed - Cancer Clinical Trials

Does Acupressure Help Reduce Nausea and Vomiting in Palliative Care Patients?

Start date: September 2005
Phase: N/A
Study type: Interventional

Randomised controlled trial of acupressure wrist bands for hospice in-patients suffering from terminal cancer who are troubled by nausea and vomiting.

NCT ID: NCT00199329 Completed - Clinical trials for Postoperative Nausea and Vomiting

Antiemetic Effect of the Addition of Ondansetron to the Morphine Solution in Patient-Controlled Analgesia (PCA)

Start date: January 2005
Phase: N/A
Study type: Interventional

PCA morphine always introduces nausea and vomiting during the postoperative period. Ondansetron can reduce PONV (postoperative nausea vomiting). We, the researchers at Khon Kaen University, are trying to add ondansetron in PCA morphine. Patients receive a small dose of ondansetron when they request morphine.

NCT ID: NCT00193999 Completed - Heart Disease Clinical Trials

Do Nasogastric Tubes After Cardiac Surgery Reduce Nausea and Vomiting

Start date: February 2003
Phase: Phase 4
Study type: Interventional

Gastric emptying is delayed after cardiac surgery, but the efficacy of the nasogastric (NG) tube in preventing distension and reducing vomiting is unclear. Nasogastric (NG) tubes are routinely used in patients undergoing surgery. They are presumed to reduce postoperative nausea and vomiting (PONV) and to lessen the risk of aspiration by reducing residual gastric volumes; however, their insertion and use is not however without potentially serious complications. Existing literature does not address their efficacy in reducing PONV after cardiac surgery. However, current evidence suggests that up to 50% of patients in this group suffer significant nausea and vomiting. The objective of this study is to determine whether NG tubes should continue to be inserted routinely during cardiac surgery to reduce PONV.