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Uterine Neoplasms clinical trials

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NCT ID: NCT01247779 Completed - Ovarian Cancer Clinical Trials

Perioperative Morbidity in Gyneco-oncology According to the Procedure : Coelioscopy Versus Robot-assisted Coelioscopy

ROBO-GYN
Start date: December 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to compare perioperative morbidity of coelioscopy versus robot-assisted coelioscopy in cervical cancer, uterus cancer and ovarian cancer.

NCT ID: NCT01247571 Completed - Clinical trials for Uterine Carcinosarcoma

Pazopanib Hydrochloride in Treating Patients With Recurrent or Persistent Uterine Cancer

Start date: January 2011
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well pazopanib hydrochloride works in treating patients with uterine cancer that has come back or has not responded to treatment. Pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Pazopanib hydrochloride may also stop the growth of uterine cancer by blocking blood flow to the tumor.

NCT ID: NCT01226264 Active, not recruiting - Recurrence Clinical Trials

Diffusion MRI; Predictive Value for Cervical Uterine Cancer Recurrence

s52647
Start date: November 2010
Phase: N/A
Study type: Interventional

Uterine cervical cancer is the second most common female malignancy. Therapy monitoring is essential to detect early recurrence. Diffusion-weighted magnetic resonance imaging is an emerging MRI imaging technique which has a potential value for the detection of primary and recurrent disease and for the assessment of response to therapy. The purpose of this project is to evaluate the predictive value of DWI during and after therapy in the prediction of recurrence of cervical uterine cancer. It will be considered whether DWI is able to provide early information about the response to therapy. This could enable the identification of less- or non-responsive tumors and in this way therapy can be adapted as soon as possible. Hence the investigators could offer the patient a more efficient treatment scheme and a reduction in toxicity related to the treatment could be established.

NCT ID: NCT01225887 Completed - Clinical trials for Endometrial Adenocarcinoma

Nintedanib in Treating Patients With Recurrent or Persistent Endometrial Cancer

Start date: October 2011
Phase: Phase 2
Study type: Interventional

This phase II trial studies the side effects and how well nintedanib works in treating patients with endometrial cancer that has come back. Nintedanib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the tumor.

NCT ID: NCT01221987 Completed - Cervical Cancer Clinical Trials

Cross-sectional Study on Human Papillomavirus Type Distribution in Adult Women Diagnosed With Cervical Cancer

Start date: October 2009
Phase: N/A
Study type: Observational

The current study will elucidate the human papillomavirus type distribution in a population of women diagnosed with cervical high grade pre-cancerous lesions and invasive cervical cancer in Sri Lanka.

NCT ID: NCT01210222 Completed - Clinical trials for Endometrial Adenocarcinoma

Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer

Start date: June 6, 2011
Phase: Phase 2
Study type: Interventional

This phase II trial studies the side effects and how well trebananib works in treating patients with persistent or recurrent endometrial cancer. Trebananib may stop the growth of endometrial cancer by blocking blood flow to the tumor.

NCT ID: NCT01208467 Completed - Clinical trials for Endometrial Adenocarcinoma

Prognostic Biomarkers in Patients With Endometrial Cancer

Start date: September 2010
Phase: N/A
Study type: Observational

This research study is studying prognostic biomarkers in tissue samples from patients with endometrial cancer. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

NCT ID: NCT01203176 Recruiting - Clinical trials for Malignant and Pre-malignant Changes in the Polyp

Incidence of Malignant and Premalignant Endometrial Polyp in Asymptomatic and Symptomatic Postmenopausal Women

Start date: September 2010
Phase: N/A
Study type: Interventional

The prevalence of endometrial polyp is 24% in the general population but is much higher in postmenopausal women. The incidence of malignant or pre-malignant findings in endometrial polyps ranges from 2 to 10% in menopausal women. Removal of endometrial polyps in postmenopausal symptomatic women is the standard of care, same goes for asymptomatic women with risk factors for endometrial malignancy, however treatment of asymptomatic postmenopausal women with endometrial polyp but no risk factors is disputable. In light of ambiguity in literature regarding the rate of malignant and pre-malignant findings in polyps in asymptomatic post-menopausal women, the investigators are asking to conduct a prospective study in order to evaluate and compare the incidence of malignant and pre-malignant changes in symptomatic and asymptomatic postmenopausal women with endometrial polyp

NCT ID: NCT01199250 Not yet recruiting - Lynch Syndrome Clinical Trials

Biomarkers in Samples From Patients With Endometrial Cancer

Start date: January 2100
Phase: N/A
Study type: Observational

This research study is studying biomarkers in samples from patients with endometrial cancer. Studying samples from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

NCT ID: NCT01198171 Not yet recruiting - Clinical trials for Stage II Uterine Corpus Cancer

Racial and Genetic Biomarkers of Response in Tissue Samples From Patients With Endometrial Cancer

Start date: January 2100
Phase: N/A
Study type: Observational

This research study is studying racial and genetic biomarkers of response in tissue samples from patients with endometrial cancer. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. DNA analysis of tumor tissue may also help doctors predict how well patients will respond to treatment.