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Uterine Neoplasms clinical trials

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NCT ID: NCT05529303 Completed - Ovarian Cancer Clinical Trials

Prolonged Grief and Perception of Femininity in Gynecological Cancer Patients

Start date: February 26, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effect of the 'Feminine Identity Improvement Program', based on cognitive behavioral and expressive techniques applied to gynecological cancer patients, on prolonged grief reactions and the perception of femininity. The study will be conducted in a randomized controlled and qualitative type with gynecological cancer patients who completed their surgical treatment at least three months ago in the last year at Afyonkarahisar Health Sciences University Hospital.

NCT ID: NCT05004623 Completed - Clinical trials for Uterine Cervical Neoplasms

Early Feasibility Study of the "Easy Light" Fluorecence Imaging System

Start date: May 26, 2021
Phase: N/A
Study type: Interventional

This is an early feasibility study to evaluate the device functionality of an open-field handheld wireless fluorecence imaging system for detection of sentinel lymph nodes in women with cervical and uterine cancers who underwent open surgery.

NCT ID: NCT04706000 Completed - Endometrial Polyp Clinical Trials

Autophagy Markers in Endometrial Polyps

Start date: January 8, 2021
Phase:
Study type: Observational

The aim of this research is to evaluate autophagy markers in patients with endometrial polyps

NCT ID: NCT04679675 Completed - Cervical Cancer Clinical Trials

Self-Testing Options in the Era of Primary HPV Screening for Cervical Cancer Trial

STEP
Start date: November 20, 2020
Phase: N/A
Study type: Interventional

The Self-Testing options in the Era of Primary HPV screening for cervical cancer (STEP) trial will evaluate effectiveness of home-based HPV kits for improving cervical cancer screening uptake and its cost-effectiveness. The investigators will compare cervical cancer screening uptake within six months among women randomized to different outreach approaches based on prior screening behavior: A) Adherent and coming due: direct mail HPV kit vs. opt-in HPV kit vs. education; B) Overdue: direct mail HPV kit vs. education; C) Unknown: opt-in HPV kit vs. education.

NCT ID: NCT04492007 Completed - Colorectal Cancer Clinical Trials

Feasibility Testing of Patient Reported Outcomes - Informed Symptom Management System (PRISMS)

PRISMS
Start date: November 2, 2020
Phase: N/A
Study type: Interventional

This is a proof-of-concept pilot randomized clinical trial to test the feasibility of the innovative Patient-Reported Outcomes-Informed Symptom Management System (PRISMS) to enhance personalized supportive care for cancer patients and caregivers during post-treatment care transition.

NCT ID: NCT04363957 Completed - Cervical Cancer Clinical Trials

Evaluation of Patient Reported Knowledge and Satisfaction Following the Use of an Enhanced Gynecologic Brachytherapy-Specific Educational Video

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

Brachytherapy is a highly technical and integral component of the definitive treatment of gynecologic cancers [1]. To enhance provider communication and patient engagement, our study investigates a video consent on impact of patient treatment-related outcomes. The study team will use a detailed brachytherapy video in addition to the standard brachytherapy verbal consent to evaluate patient-reported satisfaction and patient anxiety for gynecologic high-dose rate brachytherapy (a radiation procedure).

NCT ID: NCT04351139 Completed - Ovarian Neoplasms Clinical Trials

Impact of the COVID-19 Pandemic in Gynecological Oncology

COVID-GYN
Start date: May 6, 2020
Phase:
Study type: Observational

The current infection with the Coronavirus SARS-CoV-2 (COVID-19) is an exceptional health situation which requires an adaptation of our management practices in gynecological oncology. Data from the literature suggest that infection with Coronavirus is serious in subjects with cancer with a risk of severe form 5 times higher than that of the population without cancer and a risk of death multiplied by 8. In addition, the risk of infection would be 3 times greater in case of cancer. Faced with the COVID-19 epidemic, the investigator must organize themselves to ensure continuity in the treatment of patients with gynecological cancer but also adapt our practices in the management (CPR, teleconsultation, adaptation of treatment or even postponement of treatment). The objective of the High Council of Public Health is to be able to ensure adequate oncological care avoiding any potential loss of chance concerning the care of cancer: people affected must, despite the pandemic, have care allowing the same level of curability (localized cancers) or the same life expectancy (advanced cancers). This must be done by limiting as much as possible the impact on the organization of the service, the organization of patient follow-up and the psychological impact that these possible modifications could have. The hypotheses of our study are that the exceptional health situation linked to this pandemic leads to a change in the care of patients with gynecological cancer associated with a psychological impact and increased anxiety of patients during their care. Despite the extent of the pandemic, very little existing data makes it possible to define recommendations with a sufficient level of evidence.

NCT ID: NCT04270994 Completed - Clinical trials for Endometrial Polyps in Infertile Patients

Misoprostol as a Treatment for Endometrial Polyps in Infertile Patients

Start date: September 2016
Phase: Phase 2/Phase 3
Study type: Interventional

Endometrial polyps are one of the main causes of infertility in women. In this work we propose an alternative, effective, economical and safe treatment: the use of misoprostol

NCT ID: NCT04262089 Completed - Uterine Cancer Clinical Trials

Neo-adjuvant Pembrolizumab in dMMR/ POLE-EDM Uterine Cancer Patients: a Feasibility Study

PAM
Start date: November 1, 2020
Phase: Phase 1
Study type: Interventional

In this feasibility study the investigators intend to treat patients with high mutational uterine cancer with two cycles immune checkpoint inhibition before standard-of-care hysterectomy.

NCT ID: NCT04068675 Completed - Ovarian Cancer Clinical Trials

Effects of Centering Pre-operative Counseling on Patient Reported Anxiety

Start date: February 24, 2020
Phase: N/A
Study type: Interventional

The primary objective of the study is to evaluate the effect of pre-operative counseling in a group setting on patient reported anxiety for patients scheduled to undergo surgery for a known or suspected gynecologic malignancy. Patient reported anxiety will be evaluated using a validated Patient-Reported Outcomes Measurement Information System (PROMIS) survey. We hypothesize that the group counseling session will reduce patient reported anxiety by a clinical meaningful level. Secondary objectives will evaluate the effect of the intervention on patient reported depression levels and compare adherence to Enhanced Recovery After Surgery (ERAS) instructions, utilization of unscheduled health care resources, and anxiety/depression levels to historical controls.