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NCT ID: NCT05368142 Not yet recruiting - Diabetic Foot Ulcer Clinical Trials

Nocardia Cell Wall Skeleton for the Treatment of Diabetic Foot Ulcer Wounds

Start date: May 20, 2022
Phase: Phase 4
Study type: Interventional

This study was to investigate the efficacy and safety of Nocardia rubra Cell Wall Skeleton (NCWS) in the treatment of diabetic foot ulcer wounds. The study was a prospective, randomized, controlled, multicentre study . The subjects were randomly divided into two groups: NCWS group and control group(silver ions dressing), with a total of 116 cases and 58 cases in each group. Patients in the NCWS group received nocardia rubra cell wall skeleton for external use, in parallel with silver ions dressing treatment. The efficacy and side effects were observed, with a primary endpoint of 30-days wound healing rate.

NCT ID: NCT05341401 Not yet recruiting - Clinical trials for Ulcerative Colitis Chronic

Budesonide Multimatrix(MMX) Versus Prednisolone in Management of Mild to Moderate Ulcerative Colitis

Start date: June 2022
Phase: Phase 2/Phase 3
Study type: Interventional

My study aims to directly compare the efficacy and safety of Budesonide MMX versus Prednisolone in the management of mild to moderate cases of ulcerative colitis.

NCT ID: NCT05341206 Not yet recruiting - Clinical trials for Head and Neck Neoplasms

Evaluation the Effects of Herbal Gargle for Chemoradiotherapy-induced Oral Mucositis of Head & Neck Cancer, a Pilot Study.

Start date: April 15, 2022
Phase: Phase 2
Study type: Interventional

The aim of the study is to evaluate the effects of Herbal gargle on chemoradiotherapy-induced stomatitis in head & neck cancer patients.

NCT ID: NCT05338463 Completed - Clinical trials for Chronic Diabetic Foot Ulcer

Fespixon Cream for the Treatment of Chronic Diabetic Foot Ulcers (TEXAS 1A, 2A) in Dialysis Patients

Start date: December 1, 2021
Phase: Phase 4
Study type: Interventional

Evaluate the Safety and Efficacy of Fespixon Cream for the Treatment of Chronic Diabetic Foot Ulcers (TEXAS 1A, 2A) in dialysis patients This study aimed to evaluate the effects of a topical cream containing Plectranthus amboinicus and Centella Asiatica when applied topically to diabetic foot ulcers in uremia patients with PAOD.

NCT ID: NCT05336773 Not yet recruiting - Ulcerative Colitis Clinical Trials

Ulcerative Colitis Mayo Score With Artificial Intelligence

Start date: April 2022
Phase:
Study type: Observational

This project will use deep learning to classify colonoscopy images of different severity of ulcerative colitis, so as to assist clinicians in the accurate diagnosis of ulcerative colitis.

NCT ID: NCT05327790 Recruiting - Ulcerative Colitis Clinical Trials

LFMT vs Placebo in New Biologic Start for Ulcerative Colitis

Start date: June 3, 2022
Phase: Phase 2
Study type: Interventional

To compare the safety and efficacy of concomitant LFMT versus placebo in UC patients who are starting vedolizumab or ustekinumab.

NCT ID: NCT05324930 Completed - Diabetic Foot Ulcer Clinical Trials

Evaluating the Effectiveness of Piscean Derived Collagen Dressing on Neuropathic Diabetic Foot Ulcer in T2DM Patients

Start date: December 2, 2021
Phase: N/A
Study type: Interventional

Diabetic foot ulcers (DFU) are challenging to treat with complicated healing processes and require advanced wound care. Piscean collagen has the potential to promote the regenerative process while remaining cost-effective and with minimal side effects. In this study, the efficacy of a piscean collagen matrix dressing was compared with a standard dressing of saline-moistened gauze for wound healing in patients with neuropathic DFU. This is a double-blinded, randomised clinical trial.

NCT ID: NCT05322525 Recruiting - Clinical trials for Venous Leg Ulcers (VLU)

A Research Study to Evaluate the Safety and Potential Efficacy of ON101 Cream for the Treatment of Venous Leg Ulcers.

Start date: June 23, 2021
Phase: Phase 4
Study type: Interventional

A Research Study to evaluate the safety and potential efficacy of ON101 cream for the treatment of venous leg ulcers.The objectives of the study are to determine the safety and to explore the potential efficacy of ON101 cream in patients with venous leg ulcers.

NCT ID: NCT05321485 Recruiting - Ulcerative Colitis Clinical Trials

The Effect of MedicijnWijs on Adherence to Azathioprine Therapy in Adolescents With IBD

MEDICATION
Start date: March 16, 2022
Phase: N/A
Study type: Interventional

Medication non-adherence is an existing problem in patients with inflammatory bowel diseases (IBD). Adherence rates are especially low in children and adolescents. Good medication adherence is key in achieving lower disease activity and longer periods of remission. Previous research has shown education can increase medication adherence. MedicijnWijs is a mobile phone app containing a module concerning a 6-weeks guidance with azathioprine therapy. It provides information about IBD and azathioprine. In this multicenter before-and-after study, the aim is to assess the effect of MedicijnWijs on the adherence to azathioprine therapy in adolescents with IBD. This is done using two validated questionnaires that are translated to Dutch: the Medication Adherence Report Scale-5 (MARS-5), which tests the participants' adherence to azathioprine therapy, and the Inflammatory Bowel Disease Knowledge Inventory Device 2 (IBD-KID2), which tests the participants' knowledge about IBD. These questionnaires are filled in at the beginning of the study period and after 6 weeks of using MedicijnWijs. This way a change in both scores can be assessed. The investigators hypothesize that MedicijnWijs will help increase the adherence to azathioprine therapy in adolescents with IBD.

NCT ID: NCT05319106 Recruiting - Venous Leg Ulcer Clinical Trials

Phase Ⅱ Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Venous Leg

Start date: December 15, 2022
Phase: N/A
Study type: Interventional

This project adopts a prospective clinical trial study to compare and evaluate the efficacy of local transplantation of human umbilical cord mesenchymal stem cells combined with silver ion dressing and simple silver ion dressing in the treatment of venous lower extremity ulcer wounds. To improve the healing rate and quality of life of patients.