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Clinical Trial Summary

In this project the investigators intend to study the therapeutic potential of a personalized fibre mixture in individuals at high risk of developing T2DM, and aim to address the following key objectives: 1. To investigate whether a mixture of fermentable fibres, which differ in DP and side chains, will stimulate a broad range of SCFA-producing bacterial genera, resulting in enhanced chronic SCFA production throughout the whole colon with a large variation between individuals; 2. To unravel whether providing personalized fibre mixtures, selected based on the individuals' initial microbiota and capacity for SCFA production is crucial to successfully improve host insulin sensitivity and metabolic health


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05378295
Study type Interventional
Source Maastricht University Medical Center
Contact
Status Completed
Phase N/A
Start date November 5, 2021
Completion date April 22, 2024

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