Type 2 Diabetes Mellitus Clinical Trial
Official title:
A Randomized, Control,Open Label, Multicentre Clinical Study to Evaluate the Efficacy and Safety of Cilostazol and Probucol Alone and in Combination on Atherosclerosis Related Biomarker
1. To evaluate the efficacy of Cilostazol and Probucol alone and in combination on
atherosclerosis related biomarker
2. To evaluate the safety of Cilostazol and Probucol alone and in combination on
atherosclerosis related biomarker
Efficacy evaluation:
Primary efficacy index:
After 12 weeks of treatment, the change of arteriosclerosis related biomarker in 4 modality
groups, comparing with the base line information
Secondary efficacy index:
After 8 weeks of treatment, the change of arteriosclerosis related biomarker in 4 modality
groups, comparing with the base line information
Safety evaluation:
1. Adverse Event
2. Vital Sign and Physical Examination
3. 12-lead ECG
4. Laboratory Tests (including blood routine examination, routine urine analysis, blood
biochemistry examination, glycosylated hemoglobin)
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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