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Type 2 Diabetes Mellitus clinical trials

View clinical trials related to Type 2 Diabetes Mellitus.

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NCT ID: NCT06401733 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

Intensive Aerobic and Resistance Exercise Program (IAREP)

Start date: May 11, 2024
Phase: N/A
Study type: Interventional

A 12-weeks Intensive Aerobic and Resistance Exercise Program (IAREP) intervention will be implemented on high-risk and low-risk of cognitive impairment subjects in type 2 Diabetes Mellitus. The study aim to evaluate the effectiveness of IAREP on cognition, metabolic health, physical health, and psychological health in Type 2 Diabetes Mellitus population.

NCT ID: NCT06385704 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

Research on Changes in Intestinal Barrier Function and Gut Microbiome in Patients With Type 2 Diabetes After Duodenal Mucosal Resurfacing (DMR)

DMR-IBF-GM
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to demonstrate the effects of duodenal mucosal resurfacing (DMR) on intestinal barrier function and gut microbiota when treating uncontrolled type 2 diabetes. Subjects who underwent DMR and those who did not were enrolled, and potential differences were identified by analyzing urine and fecal samples through microbiotic analysis and High Performance Liquid Chromatography (HPLC), combined with changes in clinical data.

NCT ID: NCT06384521 Not yet recruiting - Schizophrenia Clinical Trials

Lifestyle MIND- Feasibility of Wait-list Control

MIND
Start date: June 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to examine if it is feasible to randomly assign people into two groups and participate in Lifestyle MIND (Mental Illness and/N' Diabetes) at two different times. Lifestyle MIND is a diabetes lifestyle intervention recently developed for people with serious mental illness (SMI). It is known to be helpful for people with SMI who complete it, but the investigators do not know the effect in comparison to those who do not participate in it. The main questions it aims to answer are: - Does Lifestyle MIND improve diabetes control among people with SMI? - Will the effect of Lifestyle MIND be sustained 10 weeks after program completion? - From the provider's perspective, what are the barriers of achieving optimal diabetes treatment outcomes for patients with SMI? Researchers will compare outcomes of participants in the intervention with those in the wait-list control arm, to see if there will be significant differences in blood glucose level, compliance of diabetes self-management, time staying active, number of emergency department (ED) visits and psychiatric hospitalization, and subjective well-being.

NCT ID: NCT06362265 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

A Study to Evaluate Pharmacokinetics of LY3209590 in Pediatric Participants With Type 2 Diabetes Mellitus

Start date: April 2024
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate how much of LY3209590 gets into the blood stream after a single dose and how long it takes the body to remove it in pediatric participants with Type 2 Diabetes Mellitus (T2DM). The study will last for approximately 100 days.

NCT ID: NCT06339086 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

Efficacy and Safety of Semaglutide Injection in Subjects With Type 2 Diabetes

Start date: April 2024
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to evaluate the similarities in efficacy and safety of semaglutide injection and Ozempic® in patients with type 2 diabetes who have poor glycemic control after metformin treatment. Participants will receive either a dose of semaglutide or Ozempic® once weekly (subcutaneous injection) as add-on to metformin for 32 weeks. Researchers will compare the outcomes of semaglutide and Ozempic® group to see if the efficacy, safety, pharmacokinetics, and immunogenicity of them are similar.

NCT ID: NCT06267391 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 2

Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes

ReCET
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

This study is designed to evaluate the safety and effectiveness of endoscopic intestinal re-cellularization therapy in individuals with type 2 diabetes (T2D) inadequately controlled on non-insulin glucose-lowering medications.

NCT ID: NCT06258148 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

Phase 3 Study of TG103 Injection Monotherapy in Treatment of Type 2 Diabetes Mellitus

Start date: March 2024
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-parallel, multicenter phase 3 clinical trial to evaluate the efficacy of TG103 injection 7.5mg and 15mg once a week monotherapy compared with placebo in subjects with type 2 diabetes with poor glycemic control after diet and exercise.

NCT ID: NCT06254014 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Placebo in T2DM Patients

Start date: March 1, 2024
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to investigate the efficacy and safety of JY09 versus placebo in patients with type 2 diabetes mellitus (T2DM) inadequately controlled by diet and exercise alone

NCT ID: NCT06235086 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

Phase 3 Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes Mellitus

Start date: March 2024
Phase: Phase 3
Study type: Interventional

This is a randomized, open-label, dulaglutide-controlled, multicenter Phase 3 trial to evaluate the efficacy, safety, and immunogenicity of different doses of TG103 injection in combination with metformin in subjects with type 2 diabetes with poor glycemic control treated with metformin monotherapy.

NCT ID: NCT06220773 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

A Study to Evaluate the Efficacy and Safety of BR1019A and BR1019B Combination Therapy

Start date: March 2024
Phase: Phase 3
Study type: Interventional

The objective of this clinical study is to Evaluate the Efficacy and Safety of BR1019A and BR1019B combination therapy in Patients with Essential Hypertension and Type 2 Diabetes Mellitus