Cognitive Therapy to Improve Word Finding

Traumatic Brain Injury Clinical Trial

Official title:

Learning Paradigms in Aphasia Rehabilitation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00494520
• Other study ID #: R01DC006934-01
• Status: Completed
• Phase: N/A
• First received: June 28, 2007
• Last updated: September 15, 2017
• Start date: July 2004
• Est. completion date: June 2009

Study information

• Verified date: April 2014
• Source: Georgetown University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Adults who sustain brain damage due to stroke, traumatic injury or surgery may develop difficulty finding words. This study compares the effectiveness of two behavior-based programs to improve picture naming ability in these individuals.

Description:

Difficulty finding words is common in patients with aphasia subsequent to left hemisphere stroke. This study will compare two cognitive therapies for the treatment of acquired word finding difficulties. The therapies use different types of cues. All participants will receive both therapies. Participants in this study will undergo a comprehensive and detailed assessment of language and other cognitive skills. The two treatments will be compared for their efficacy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 78
• Est. completion date: June 2009
• Est. primary completion date: June 2009
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Word finding difficulty subsequent to stroke, traumatic brain injury, brain surgery or other brain damage occuring at least 6 month prior to participation

• Ability to attend 2 sessions per week for several months at Georgetown University in Washington, DC

Exclusion Criteria:

• History of learning disabilities

• Best corrected vision less than 20/40

• Corrected hearing within functional limits

• Less than 10 years formal education

• Significant memory or comprehension problems

Related Conditions & MeSH terms

• Anomia
• Aphasia
• Brain Injuries
• Cerebrovascular Accident
• Stroke
• Traumatic Brain Injury

Intervention

Procedure:
• Errorful training condition
Errorful training condition: Participant saw a picture and named it without any cues. If an error was produced, the cue with the least amount of information was provided (e.g. for "pumpkin", "pu"). Cues with increasing information were provided until the picture was correctly named (e.g. for "pumpkin": "pump", "pumpki", then "pumpkin"). Once the correct name was provided, the trial ended.
• Errorless training condition
Errorless learning (EL) condition: Participant saw a picture with its name, and repeated the word. The participant continued to name the picture as the auditory cues provided less and less of the word (e.g. for "banana" she would hear "banan", "bana" then "ba" and finally no cue). If an error was produced at any stage, the whole word was presented, the participant repeated it, and the trial ended.

Locations

Country	Name	City	State
United States	Georgetown University Medical Center	Washington, D.C.	District of Columbia

Sponsors (1)

Lead Sponsor	Collaborator
Georgetown University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Improved picture naming of trained words.	Overall accuracy of named trained items	Following conclusion of word treatment.
Secondary	Improved picture naming of trained words.	Overall accuracy of named trained items	At 6 months after conclusion of word treatment
Secondary	Improved picture naming of untrained words.	Overall accuracy of named untrained items	Following conclusion of word treatment.
Secondary	Improved picture naming of untrained words.	Overall accuracy of named untrained items	At 6 months after conclusion of word treatment

External Links

•   Cognitive Neuropsychology Lab at Georgetown University Medical Center