Clinical Trials Logo

Tinea Capitis clinical trials

View clinical trials related to Tinea Capitis.

Filter by:

NCT ID: NCT06400056 Not yet recruiting - Fungal Resistance Clinical Trials

Clinical and Laboratory Evaluation of Antifungal Resistance in Tinea Capitis

Start date: May 2024
Phase: Phase 1
Study type: Interventional

AIM OF WORK : 1. Detect the most common fungal strains that cause tinea capitis 2. Detect Different effectiveness of terbinafine in different cases 3. Detect the resistant strains. 4. Detect the mycological and the clinical cure rates upon using systemic terbinafine in treatment of tinea capitis

NCT ID: NCT04144491 Completed - Diarrhea Clinical Trials

Effect of L. Rhamnosus Yoba on RTI and Other Health Outcomes Among Children (3-6 Years) in Uganda

Start date: September 16, 2019
Phase: N/A
Study type: Interventional

This is a nutritional trial with two arms: 1) Intervention arm of Probiotic Yoghurt containing Lactobacillus rhamnosus yoba 2012 and 2) Control arm of custard-like dairy product. The study subjects are 200 children between the age of 3-6 years that attend a school in Southwestern Uganda, Sheema district. Children will be randomized and enrolled in either the yoghurt (100 children) or the placebo (100 children) arm. The children will be monitored for 3 weeks in the baseline in regards to the incidence of common childhood diseases. During these three weeks, stool, saliva and urine samples will be collected. Also measurement of anthropometric indicators (weight and height) will take place. Subsequently, the children will consume either 100ml yoghurt or 100ml placebo product, once per day for five days per week for nine weeks, while being daily monitored in regards to the incidence of common childhood diseases. The same samples (stool, urine and saliva) and assessments (anthropometric) will take place at end line.

NCT ID: NCT02725255 Completed - Anemia Clinical Trials

Design and Clinical Evaluation of a School Meal With Deworming Properties

Start date: May 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Intestinal parasites (IP) are among the world's neglected tropical diseases. Morbidity due to IPs is greatest in school-age children who typically have the highest burden of infection. In 2001, WHO passed a resolution for the use of large-scale mass drug administration (MDA) of antihelminthic drugs to deworm children in developing countries. Though initially effective, there is concern that MDA might not be sustainable over extended periods especially considering the large children populations and the high frequency of dosing. Further, the MDAs exert increasing drug pressure on parasite populations, a circumstance that is likely to favor parasite genotypes that can resist anthelmintic drugs. There is hence a need for alternatives that are not only affordable and sustainable but easier to implement in the long term with a minimal chance of development of resistance. The investigators propose to develop and test the feasibility of a corn porridge meal fortified with papaya fruit extracts that have been shown to have antihelminthic properties. The investigators intend to evaluate its efficacy when given through school feeding programs and compare the outcome with albendazole- the recommended MDA agent for deworming school children. The investigators will design and formulate the product and test it among children in three primary schools in Western Kenya.

NCT ID: NCT02658292 Withdrawn - Tinea Capitis Clinical Trials

Safety and Efficacy of NAFT900 in Children With Tinea Capitis

Start date: n/a
Phase: Phase 2
Study type: Interventional

A Double-Blind, Randomized, Vehicle-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of NAFT-900 in Children Aged 6 to < 13 Years with Tinea Capitis

NCT ID: NCT02550496 Completed - Tinea Capitis Clinical Trials

Evaluation of Trichoscopy in the Diagnosis of Tinea Capitis

ETDT
Start date: March 4, 2015
Phase: N/A
Study type: Interventional

Waiting for a proof by mycological culture is usually necessary before starting a systemic antifungal therapy. It therefore seems to us interesting to evaluate the benefit of using dermoscopy in clinical diagnosis of Tinea Capitis.

NCT ID: NCT02238912 Completed - Clinical trials for Tinea Infections Such as Tinea Corporis, Tinea Cruris, Tinea Pedis, Tinea Mannum, Tinea Barbae, Tinea Capitis Are Studied

Evaluation of Preclinical Toxicity andTherapeutic Efficacy of Kandhaga Rasayanam in Padarthamarai

KR
Start date: June 2012
Phase: Phase 2
Study type: Interventional

this study is intended to find out the therapeutic efficacy of the siddha drug Kandhaga Rasayanam in Padarthamarai ( Ring worm infection )

NCT ID: NCT00645242 Completed - Tinea Capitis Clinical Trials

A Study Of Diflucan In Children With Ringworm Of The Scalp

Start date: November 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of fluconazole for the treatment of tinea capitis in pediatric patients aged 3 to 12 years.

NCT ID: NCT00224926 Completed - Tinea Capitis Clinical Trials

The Natural Course of Trichophyton Tonsurans Carriage and Infection: A Molecular and Biochemical Evaluation

Start date: September 2003
Phase: N/A
Study type: Observational

To explore carrier and infection status of T.tonsurans tinea capitis and characterize the host-pathogen interaction as it relates to the disease presentation. The general hypothesis for this study is as follows: the type of genotypic and phenotypic variant to which a child is exposed accounts for the presentation status observed in Trichophyton tonsurans infection.The global outcome of this investigation is to reveal potential new drug targets designed to improve treatment outcomes in these children.

NCT ID: NCT00127868 Completed - Tinea Capitis Clinical Trials

Selenium Sulfide, Ketoconazole and Ciclopirox Shampoo as Additional Treatments for Tinea Capitis (Scalp Ringworm)

Start date: March 2005
Phase: N/A
Study type: Interventional

Antifungal shampoos have been used as supplements to oral griseofulvin to help eradicate tinea capitis (also known as ringworm of the scalp) more quickly. While selenium sulfide shampoo has been the gold standard, its strong odor and its drying effect on the scalp discourage many patients from using it. Meanwhile, no other antifungal shampoo has been rigorously evaluated for efficacy. Therefore, while physicians are prescribing griseofulvin accompanied by any of a number of antifungal shampoos for tinea capitis, it is not known which antifungal shampoos (excluding selenium sulfide) actually significantly reduce time to cure, nor which do so the fastest. Scalp ringworm can also re-occur in the same child. To date, no studies have been done to find out whether or not the use of antifungal shampoos can prevent the recurrence of scalp ringworm. In this study, children ages 1-12 years old, who have clinically diagnosed tinea capitis, will all be prescribed oral griseofulvin for 8 weeks. In addition, they will be randomly assigned to use either selenium sulfide shampoo, ketoconazole shampoo, ciclopirox shampoo, or baby shampoo twice a week for 8 weeks. After 8 weeks, griseofulvin will be stopped. All patients will continue using the same assigned shampoo twice weekly for 24 weeks, while continuing to return to clinic every 4 weeks for scalp evaluation.

NCT ID: NCT00117767 Completed - Tinea Capitis Clinical Trials

Terbinafine Compared to Griseofulvin in Children With Tinea Capitis

Start date: June 2004
Phase: Phase 3
Study type: Interventional

Tinea capitis is a dermatophyte infection of the scalp hair follicles, which occurs primarily in children. Hair loss, hair breakage, scaling, plus various degrees of erythema, pustules and pruritus are the primary clinical signs which can be associated with tinea capitis. The infection is caused by a relatively small group of dermatophytes in the genera Trichophyton and Microsporum. Terbinafine hydrochloride is a synthetic allylamine derivative antifungal agent. This study will evaluate the efficacy and safety of terbinafine in children with tinea capitis.