Thrombosis Clinical Trial
Official title:
Thromboprophylaxis in Patients Undergoing Orthopedic Surgeries; Using Propensity Score Matching
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism
(PE), is a common post-operative complication. The necessity for anticoagulant therapy after
orthopedic surgeries is widely understood, but treatment administration patterns in the
prevention of venous thromboembolism (VTE) after orthopedic surgeries during the hospital
stay have yet to be examined.
The main objective of this study is to perform a comparative effectiveness review examining
the benefits and harms associated with venous thromboembolism prophylaxis in patients
undergoing orthopedic surgeries.
It is around efficacy and safety evaluation of using anticoagulant for thromboprophylaxis in
patients undergoing orthopedic surgeries taking into the account the reliable selection of
patients most benefit.
The aims of this study is to analyze patient records in teaching hospitals database of our
country (including: Hanoi Medical University, Bach Mai Hospital, Cho Ray Hospital, Viet Duc
University Hospital) and compare the outcomes and costs between different types of
anticoagulant medications that were prescribed for the prevention of VTE following orthopedic
surgeries. This analysis will assess and quantify the outcomes, resource utilization, and
cost of care for patients receiving rivaroxaban or enoxaparin. The outcomes of interest
include the occurence of DVT and PE, rates of major bleeds, medical resource utilization, and
total costs (medical plus pharmacy).
n/a
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