Thrombosis Clinical Trial
Official title:
Atorvastatin Toronto Retinal Vein Occlusion Study (ATORVO)
The ATORVO study is designed to determine whether atorvastatin (Lipitor) can improve vision, when compared to placebo
Retinal vein occlusion (RVO), a common cause of visual loss in the Western world, is a
disease whose etiology resembles that of classic atherosclerosis. A therapy that lowers the
risk of arterial and venous thrombosis would seem to be a reasonable approach to managing
this disease, for which there is currently no treatment.
ATORVO is a randomized double-masked clinical trial comparing a daily dose of 80 mg of
atorvastatin to matched placebo in persons recently diagnosed with RVO. At 24 weeks after
randomization, we will evaluate each participant's visual acuity and the presence of
secondary complications related to RVO.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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