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Thoracic Diseases clinical trials

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NCT ID: NCT04190719 Recruiting - Clinical trials for Cardiovascular Diseases

Patient Empowerment for Major Surgery Preparation @ Home

Paprika
Start date: January 3, 2020
Phase: N/A
Study type: Interventional

Non-randomized monocentric open cohort study vs historical comparative group testing the efficacy of a multimodal prehabilitation program (based on physical activity, nutritional support and mental preparation) for unfit patients based on nutrition, physical activity and mental preparation in reducing postoperative complications in elective major surgery

NCT ID: NCT04118660 Recruiting - Lung Cancer Clinical Trials

Thoracic Specimen Registry

Start date: March 1, 2017
Phase:
Study type: Observational [Patient Registry]

The purpose of the registry will be to support ongoing research in the etiology, early diagnosis, clinical management, and prognosis of lung cancer and other cancers and diseases of the thorax by developing a complete repository of specimens from patients with thoracic disease including but not limited to suspected lung cancer, mediastinal and pleural tumors, lung transplants and from patients at a very high risk of developing other thoracic cancers or other thoracic diseases.

NCT ID: NCT03922516 Completed - Lung Diseases Clinical Trials

Accuracy of Ultra-Low-Dose-CT of the Chest Compared to Plain Film in an Unfiltered Emergency Department Patient Cohort

UP-Chest
Start date: May 2, 2019
Phase: N/A
Study type: Interventional

This trial compares the accuracy provided by plain film as well as ultra-low-dose-computed-tomography (ULDCT) of the chest. It also aims to analyze differences in diagnostic confidence and therapeutic consequence offered by these two imaging modalities.

NCT ID: NCT03904082 Enrolling by invitation - Thoracic Diseases Clinical Trials

Comparison of Postoperative Analgesic Consumption of the Erector Spina Plane Block and Serratus Anterior Plane Block

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

To evaluate the ability of Erector spina Plane block and Serratus Anterior Plane block to decrease postoperative pain and analgesia requirements in patients undergoing thoracotomy.

NCT ID: NCT03768193 Completed - Pain, Postoperative Clinical Trials

Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery

SAPB
Start date: October 4, 2017
Phase: N/A
Study type: Interventional

Thoracic surgery, and surgery involving the chest wall in general, is associated with poorly controlled acute pain, which may result in delayed functional recovery, and may progress to chronic pain. Multimodal opioid-sparing analgesia regimens are a key component of the thoracic surgery enhanced recovery pathway, the aim of which is to improve outcomes in patients undergoing both minimally invasive and open thoracic surgical procedures. Novel interfascial plane blocks are emerging as feasible alternatives to central neuraxial analgesia techniques in a variety of clinical settings. The aim of this study is to show non-inferiority of serratus anterior blockade compared with surgically placed paravertebral blocks in the management of perioperative acute pain in patients undergoing VATS procedures.

NCT ID: NCT03729999 Completed - Thoracic Diseases Clinical Trials

Ultrasound to Verify Lung-isolation During Single-lung Ventilation

Start date: December 12, 2018
Phase: N/A
Study type: Interventional

The purpose of the current study is to prospectively evaluate the usefulness of thoracic ultrasonography in demonstrating effective lung isolation during single-lung ventilation (SLV) in the pediatric patient. The primary hypothesis is that ultrasonography will accurately verify lung separation during SLV, as compared to fiberoptic bronchoscope (FOB).

NCT ID: NCT03677856 Recruiting - Anesthesia Clinical Trials

The Effectiveness of ThOracic Epidural and Paravertebral Blockade In Reducing Chronic Post- Thoracotomy Pain: 2

TOPIC-2
Start date: January 8, 2019
Phase: N/A
Study type: Interventional

An estimated 7200 thoracotomies (surgical incision into the chest wall) are performed annually in the UK, most commonly to treat lung cancer. It is considered one of the most painful surgical procedures due to tissue, muscle and nerve damage from the incision, and as the wound heals. The normal breathing motion and nerve injury caused during surgery can result in a high risk of persistent pain for months after surgery. Chronic post-thoracotomy pain (CPTP) is defined as pain that recurs or persists at least two months following the surgery and can occur in up to half of these patients. There are two commonly used for pain control during thoracotomy: Thoracic Epidural Block (TEB) blocks nerves on both sides of the chest at the spinal cord. It reduces painful nerve signals but may not abolish them completely. Para Vertebral Blockade is done only on the side of surgery and may completely block painful nerve signals from reaching the spinal cord. This total blockade of nerve signals could decrease the likelihood of developing chronic pain and could be uniquely effective in preventing long-term pain. Over a period of 30 months this trial will be attempting to approach all patients undergoing a thoracotomy at approximately 20 UK hospitals to see if they wish to participate, and to look at the reasons they may not want to participate. We will follow up each participant for a maximum of a year following their surgery. There is a qualitative intervention embedded within this study to support recruitment.

NCT ID: NCT03515811 Completed - Thoracic Diseases Clinical Trials

A Post Market Study to Confirm the Safety and Performance of the Signia™ Stapling System.

Start date: January 22, 2019
Phase:
Study type: Observational

The objectives of this prospective, two-arm, multicenter post-market study is to confirm safety and performance through the incidence of subjects reporting serious adverse device effects (ADEs) up to and including 30 days following use of Signia™ Stapling System with Endo GIA™ with Tri-Staple™ Technology and Tri-Staple™ 2.0 Intelligent Reloads in subjects undergoing indicated abdominal or thoracic procedures for resection, transection and creation of anastomosis per the IFU.

NCT ID: NCT03508830 Completed - Postoperative Pain Clinical Trials

Minimally Invasive Thoracic Surgery Intercostal Nerve Block Trial

Start date: December 30, 2018
Phase: Phase 3
Study type: Interventional

The Minimally Invasive Thoracic Surgery Intercostal Nerve Block Trial is a single center, double-blind, randomized, active-comparator controlled clinical trial to assess the analgesic efficacy of intercostal nerve block by Liposomal Bupivacaine versus Standard Bupivacaine in subjects undergoing lung resection by robotic or video-assisted thoracoscopic surgery.

NCT ID: NCT03496987 Completed - Pleural Effusion Clinical Trials

Vacuum vs Manual Drainage During Unilateral Thoracentesis

Start date: December 1, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if there are any differences in terms of safety, pain, or drainage speed between thoracenteses via manual drainage vs vacuum suction.