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Clinical Trial Summary

Presently no generally effective treatments for tardive dyskinesia (TD) are available. D-serine is a naturally occurring amino acid that acts in-vivo as positive allosteric modulator at the glycine site associated with the glutamatergic NMDA receptor. Previous studies have suggested that D-serine may improve motor symptoms, including dyskinesias, which are caused by treatment with presently used antipsychotics drugs.

The hypothesis under investigation in the present study is that D-serine adjuvant treatment may improve TD in schizophrenia patients diagnosed with this disorder.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT01804920
Study type Interventional
Source Herzog Hospital
Contact
Status Active, not recruiting
Phase N/A
Start date January 2013
Completion date January 2019

See also
  Status Clinical Trial Phase
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