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Syndrome clinical trials

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NCT ID: NCT00419107 Terminated - Turner Syndrome Clinical Trials

Beta Cell Function in Women With Turner Syndrome

Start date: November 2004
Phase: N/A
Study type: Observational

Diabetes is more frequent in women with Turner syndrome. The purpose of this study is to see, in what ways the glucose metabolism is different in this study population. The hypothesis is that women with Turner Syndrome have an impaired insulin production (beta cell function).

NCT ID: NCT00418821 Terminated - Clinical trials for Mucopolysaccharidosis I

A Study of the Effect of Aldurazyme® (Laronidase) Treatment on Lactation in Female Patients With Mucopolysaccharidosis I (MPS I) and Their Breastfed Infants

Start date: October 22, 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if laronidase is present in the breast milk of post-partum women receiving Aldurazyme® (laronidase) and the effects of Aldurazyme (laronidase) on the growth, development, and immunologic response of their breastfed infants.

NCT ID: NCT00418665 Completed - Clinical trials for Myelodysplastic Syndromes

A Safety and Efficacy Study to Evaluate AMG 531 Treatment in Subject With Myelodysplastic Syndrome Receiving Revlimid

Start date: December 2006
Phase: Phase 2
Study type: Interventional

This is a dose and schedule finding study of AMG 531 designed to assess the activity of AMG 531 to reduce the rate of clinically significant bleeding and blood transfusions in subjects with myelodysplastic syndrome (MDS) receiving lenalidomide. Subjects with MDS that are planned to receive at least four cycles of lenalidomide for treatment of their disease are appropriate to screen for this study. All subjects meeting the eligibility criteria will receive lenalidomide 10 mg capsule by mouth daily every day of each 28-day cycle. Subjects will receive AMG 531 or placebo once a week by subcutaneous injection for 16 weeks.

NCT ID: NCT00417794 Completed - Clinical trials for Fetal Alcohol Syndrome

Assess the Effectiveness of Atomoxetine in Children With Fetal Alcohol Syndrome and ADD/ADHD

B4Z-MC-X017
Start date: August 2005
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if atomoxetine hydrochloride improves inattention, hyperactivity, and impulsivity problems in children exposed to alcohol during birth.

NCT ID: NCT00417170 Completed - Metabolic Syndrome Clinical Trials

Comparison of Aliskiren and Amlodipine on Insulin Resistance and Endothelial Dysfunction in Patients With Hypertension and Metabolic Syndrome

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study was to determine the effects of Aliskiren on insulin resistance (IR) and endothelial dysfunction (ED) in patients with high blood pressure and metabolic syndrome. The efficacy of Aliskiren was compared to Amlodipine.

NCT ID: NCT00417144 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Comparison Between GnRH Agonist and GnRH Antagonist Protocols of Ovarian Stimulation in PCOS Patients

Start date: November 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare pregnancy rates and the occurrence of OHSS in PCOS patients who were treated with GnRH agonist and GnRH antagonist protocols ovarian stimulation during an IVF cycle. Our hypothesis is that the GnRH antagonist protocol reduces the occurrence and severity of OHSS compared to the GnRH agonist protocol.

NCT ID: NCT00416741 Completed - Metabolic Syndrome Clinical Trials

Assessing The Treatment Effect in Metabolic Syndrome Without Perceptible diabeTes (ATTEMPT)

ATTEMPT
Start date: February 2005
Phase: Phase 4
Study type: Observational

The objective of this protocol is to improve awareness, treatment, and control of metabolic syndrome, within primary prevention of cardiovascular disease, by implementing guidelines, after training of the participating physicians.

NCT ID: NCT00416260 Completed - Clinical trials for Respiratory Distress Syndrome, Adult

Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome

Start date: July 2006
Phase: Phase 1/Phase 2
Study type: Interventional

In the past five years, there is a growing body of published evidence on the feasibility, and oxygenation and lung protection benefits of high frequency oscillation (HFO) in the acute respiratory distress syndrome (ARDS). The investigators have recently demonstrated the short term feasibility and additional benefits with respect to oxygenation of HFO combined with tracheal gas insufflation (TGI). In the present clinical trial, the investigators intend to test the hypothesis that HFO-TGI may result in improved respiratory physiology and clinical course compared to low tidal volume conventional mechanical ventilation in patients with severe ARDS.

NCT ID: NCT00415948 Completed - Clinical trials for Acute Coronary Syndrome (ACS)

Myeloperoxidase and Multi-Markers In the Diagnosis of Diagnoses of Acute Coronary Syndrome (MIDAS) - Sample Procurement

Start date: December 2006
Phase: N/A
Study type: Observational

The purpose of the study is to procure blood samples from patients who present to the Emergency Department with suspected ACS (Acute Coronary Syndrome).

NCT ID: NCT00414310 Completed - Clinical trials for Myelodysplastic Syndrome

Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)

Start date: December 2006
Phase: Phase 2
Study type: Interventional

The goal of this clinical research study is to find out if decitabine, given with or without valproic acid, can help to control AML or MDS. The safety of both treatments will also be studied.