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Syndrome clinical trials

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NCT ID: NCT02011854 Recruiting - Clinical trials for Shoulder-hand Syndrome

Acupuncture for Post-stroke Shoulder-hand Syndrome

Start date: October 2013
Phase: Phase 2/Phase 3
Study type: Interventional

Shoulder-hand syndrome,a common complication of stroke patient,which is an important factor of limb function recovery.This research aims to observe the effect and safety of Acupuncture and Traditional Chinese medicine Combined with Rehabilitation Therapy for Post-stroke Shoulder-hand Syndrome.Furthermore, the investigators will promote the treatment in community hospital.

NCT ID: NCT02011776 Completed - Dry Eye Syndromes Clinical Trials

A Randomized, Parallel-Group Comparison Study of Topical Corticosteroids in Dry Eye Patients With Sjögren Syndrome

Start date: March 2013
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of this study is to evaluate the effectiveness of fluorometholone combined with sodium hyaluronate eye drops in the treatment of Sjögren syndrome.

NCT ID: NCT02011360 Completed - Childhood Obesity Clinical Trials

Prader-Willi Syndrome Macronutrient Study

Start date: May 2014
Phase: N/A
Study type: Interventional

The overall objective is to explore the mechanisms by which macronutrients regulate food intake and weight gain in Prader Willi Syndrome (PWS). Previous studies from the investigators' labs suggest that the increased appetite of PWS may be triggered or maintained by an increase in the levels of ghrelin, an appetite-stimulating hormone produced primarily by the stomach. This study will compare the effects of low carbohydrate diet versus low fat diet on levels of ghrelin, appetite suppressing hormones and markers of insulin sensitivity in patients with PWS. The investigators hypothesize that the low carbohydrate diet will suppress plasma active ghrelin and increase appetite-suppressing hormones to a greater degree and for longer duration than the low fat diet and will thereby reduce hyperphagia and increase satiety. The investigators also hypothesize that the low carb diet will improve hormonal and metabolic markers (fatty acids, amino acids and organic acids) of insulin sensitivity and inflammatory cytokine profiles of children with PWS.

NCT ID: NCT02011191 Completed - Clinical trials for End Stage Renal Disease

Biotin Deficiency and Restless Legs Syndrome

Start date: December 2006
Phase: N/A
Study type: Interventional

Restless Leg Syndrome (RLS) is a common neuropathic disorder in patients with end stage renal disease (ESRD). Study Design: Because micronutrient depletion has been associated with RLS in ESRD and because the vitamin biotin is dialyzable, the investigators examined the relationship between biotin status and RLS in ESRD. Objectives: To assess the prevalence of biotin deficiency in those with and without RLS (Study 1) and to determine the effect of biotin supplementation on RLS symptoms (Study 2) in patients receiving chronic dialysis due to ESRD.

NCT ID: NCT02010645 Terminated - Leukemia Clinical Trials

Eltrombopag With Decitabine in Advanced Myelodysplastic Syndrome (MDS)

Start date: March 2014
Phase: Phase 2
Study type: Interventional

The goal of this clinical research study is to learn if eltrombopag given in combination with decitabine can help to control advanced MDS. The safety of this study drug combination will also be studied.

NCT ID: NCT02009878 Completed - Clinical trials for Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Start date: November 2013
Phase: Phase 1/Phase 2
Study type: Interventional

This is a study to evaluate how the body handles and metabolizes (PK) the various doses of the drug Tolvaptan, and what the effect (PD) of the various doses of Tolvaptan are on the content of "salt" in blood and urine

NCT ID: NCT02008318 Completed - Clinical trials for Myelodysplastic Syndromes

A Study of Galunisertib in Participants With Myelodysplastic Syndromes

Start date: March 2014
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to investigate the effect of the study drug known as galunisertib in participants with myelodysplastic syndromes (MDS). Participants with different degrees of disease (very low, low, and intermediate risk) will be studied. The study treatment is expected to last about 6 months for each participant.

NCT ID: NCT02004665 Recruiting - Clinical trials for Acute Coronary Syndrome

Incidence and Prognostic Value of DELIRIUM in Patients With Acute CORonary synDrome: an observatIonal Study

Start date: December 2013
Phase: N/A
Study type: Observational [Patient Registry]

to evaluate the incidence of delirium in patients with acute coronary syndrome and its correlation with adverse events

NCT ID: NCT02004158 Completed - Clinical trials for Acute Coronary Syndrome

Positive Psychology to Improve Healthy Behaviors After an Acute Coronary Syndrome

PEACE II
Start date: November 2013
Phase: N/A
Study type: Interventional

In this proof-of-concept study, the investigators will assess the ease and usefulness of a positive psychology program in patients with acute coronary syndrome and less-than-optimal adherence to health behaviors. The investigators believe that positive psychology (a field that studies boosting positive emotions rather than simply reducing negative emotions) will help this cardiac population to be more healthy. The investigators want to determine whether this positive psychology program has the potential to be an adjunctive treatment for cardiac populations.

NCT ID: NCT02004067 Completed - Clinical trials for Evaporative Dry Eye Disease

Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease

Start date: January 2013
Phase: Phase 4
Study type: Interventional

In the present study the investigators aim to determine the efficacy of an immunomodulating topical medication, compared with a topical lubricant, on the treatment of dry eye disease (DED) due to primary or secondary Sjögren's syndrome (aqueous deficient DED) and evaporative DED.