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Syndrome clinical trials

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NCT ID: NCT03273985 Completed - Clinical trials for Myofascial Pain Syndrome

Effectiveness of Dry Needling in Shortened Triceps Surae Muscle

DN-TS
Start date: September 15, 2017
Phase: N/A
Study type: Interventional

To date, there are not studies about the effectiveness of dry needling versus ischemic compression in the triceps surae trigger points. A randomized clinical trial is carried out. A sample of 30 subjects are recruited and allocated into dry needling (n = 15) and ischemic compression (n = 15). Outcome measurements such as dorsal flexion range of motion, plantar pressures, temperature, superficial muscle activity and trigger points pressure pain threshold are measured immediately before and after treatment.

NCT ID: NCT03273764 Completed - Clinical trials for Respiratory Distress Syndrome in Premature Infant

Clinical RD (Respiratory Distress) Score for Objective Decision Making for Surfactant Therapy

Start date: January 1, 2015
Phase: N/A
Study type: Observational

To develop a comprehensive ʻClinical RD score' for decision making for administration of Surfactant in respiratory distress syndrome in preterm infants with gestation of 26 0/7 - 34 6/7 weeks and to assess the validity of this ʻclinical RD score' on a different subgroup of patients with similar gestational age.

NCT ID: NCT03272633 Terminated - Clinical trials for Acute Lymphoblastic Leukemia

Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies

Start date: October 26, 2020
Phase: Early Phase 1
Study type: Interventional

This pilot clinical trial studies the side effects of irradiated donor cells following stem cell transplant in controlling cancer in patients with hematologic malignancies. Transfusion of irradiated donor cells (immune cells) from relatives may cause the patient's cancer to decrease in size and may help control cancer in patients receiving a stem cell transplant.

NCT ID: NCT03269032 Completed - Clinical trials for Irritable Bowel Syndrome

Mediterranean Diet and the Gut Microbiome

Start date: October 10, 2017
Phase: N/A
Study type: Interventional

This study will evaluate the impact of a Mediterranean-style diet on microbiome diversity compared to a typical American diet. The study will observe the microbiome composition comparisons in healthy volunteers as well as in patients with Irritable Bowel Syndrome with Diarrhea (IBS-D) to see if the consumption of a Mediterranean-style diet has a positive effect on improving symptoms of IBS-D.

NCT ID: NCT03268954 Active, not recruiting - Clinical trials for Myelodysplastic Syndrome

Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML)

PANTHER
Start date: November 28, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the combination of pevonedistat and azacitidine improves event-free survival (EFS) when compared with single-agent azacitidine. (An event is defined as death or transformation to AML in participants with MDS or CMML, whichever occurs first, and is defined as death in participants with low-blast AML).

NCT ID: NCT03268811 Completed - Clinical trials for Short Bowel Syndrome

A Study in Japanese Children With Short Bowel Syndrome Who Completed SHP633-302

Start date: August 23, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this clinical study is to evaluate the long-term safety and tolerability of teduglutide treatment in Japanese pediatric participants with short bowel syndrome (SBS) who completed Study SHP633-302 (NCT02980666).

NCT ID: NCT03268733 Recruiting - Clinical trials for Polycystic Ovary Syndrome

The Effects of Folic Acid on Sudanese Women With Polycystic Ovary Syndrome

FolicacidPCOS
Start date: September 1, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

An open clinical trial

NCT ID: NCT03267901 Completed - Metabolic Syndrome Clinical Trials

Effects of Daily Walnut Intake Among the Subjects With Metabolic Syndrome

Start date: May 1, 2015
Phase: N/A
Study type: Interventional

Investigators planed to conduct a randomized, controlled, crossover trial to examine the effects of daily walnuts intake among Korean subjects with metabolic syndrome. Primary objective of this study was to investigate the effects of daily walnut intake on changes of metabolic syndrome indices in Koreans with metabolic syndrome age over 30 years old. This study was consisted of four periods: run-in, first intervention, wash-out, and second intervention phases. As 16 weeks of first intervention period began after the run-in phase, the subjects were randomly assigned into one of two groups: walnut group and control group. Participants in walnut group consumed 45 grams of walnuts on a daily basis and participants in control group were provided iso-caloric white bread for first 16 weeks. After the first intervention and wash-out period (6 weeks), second intervention which is crossover of first intervention was started during the next 16 weeks. Anthropometric measurements and biochemical analyses were done at the beginning and the end of each intervention (0, 16, 22, and 38 weeks of trial). Habitual diet was randomly observed using 3-day diet record once during each phase. Investigators expected to evaluate 1)effects of walnut ingestion on reverting metabolic syndrome to normal status especially by reducing waist circumference and improving serum levels of triglyceride and high-density lipoprotein, 2)beneficial effects of daily walnut consumption on changes of body composition in the subjects with metabolic syndrome, and 3)regulatory effects of daily walnut intake on inflammatory markers and diabetic markers.

NCT ID: NCT03267602 Completed - Down Syndrome Clinical Trials

Role of Sleep Apnea in the Neuropsychological Function in Down Syndrome People

Start date: December 2012
Phase: N/A
Study type: Interventional

This is the first study about Neuropsychological function and OSAS in Taiwan. Although the correlation between OSAS and neuropsychological abnormalities had been reported, it is worth to understand more about the detailed domains that involved in our cohort. After this, investigators can dissect the cause of mental retardation in DS and help for further treatment strategies.

NCT ID: NCT03266055 Active, not recruiting - Metabolic Syndrome Clinical Trials

Effects of Blueberry on Gut Microbiota and Metabolic Syndrome

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

There is growing evidence that nutritional intervention with dietary polyphenols can positively modulate the gut microbiota to improve cardiometabolic health. Whether the beneficial effects of blueberries on obesity and the metabolic syndrome can be linked to their potential impact on the gut microbiota and intestinal integrity remains speculative at this time. Moreover, the mechanisms of action underlying health benefits associated to blueberry consumption are still unknown. The investigators are thus proposing to combine the study of metagenomics, transcriptomics and metabolomics to test whether a prebiotic activity of highbush blueberries can play a role in the prevention of obesity-linked metabolic syndrome in a clinical setting.