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Syndrome clinical trials

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NCT ID: NCT05135572 Completed - Clinical trials for Tarsal Tunnel Syndrome

Tarsal Tunnel Syndrome and Fibromyalgia

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Widespread pain is observed in patients diagnosed with fibromyalgia, and lower extremity and foot pain are also common. In our study, we aimed to evaluate the relationship between foot pain and tarsal tunnel syndrome in female patients diagnosed with fibromyalgia.

NCT ID: NCT05134584 Recruiting - Clinical trials for Functional Dyspepsia

Efficacy of Linaclotide in Patients With Overlapping Functional Gastrointestinal Disorders

Start date: January 1, 2021
Phase: Phase 4
Study type: Interventional

This study aims to assess the efficacy and safety of linaclotide in patients with overlapping symptoms of both functional dyspepsia (FD) and constipation-predominant irritable bowel syndrome (IBS-C).

NCT ID: NCT05134220 Recruiting - Clinical trials for Acute Coronary Syndrome

Electrolytes in Chronic Kidney Disease Patients With Acute Coronary Syndrome

Start date: November 30, 2021
Phase:
Study type: Observational

Study of serum calcium and phosphorus level in chronic kidney disease patients and its relation to occurrence of acute coronary syndrome in them.

NCT ID: NCT05133050 Not yet recruiting - Alport Syndrome Clinical Trials

Safety and Efficacy of ACEI in Alport Syndrome Patients With COL4A3/COL4A4/COL4A5 Variants

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Alport syndrome (AS) is the second most common monogenic cause of end-stage renal failure (ESRF). AS is caused by variants in the COL4A3, COL4A4, and COL4A5 genes, which encode for the a3, a4, and a5 chains of type IV collagen. This trial is a prospective, randomized, controlled and multicenter trial. Mainly to assess the safety and efficacy of ramipril in Alport syndrome patients with variants of COL4A3/COL4A4/COL4A5.

NCT ID: NCT05131542 Completed - Down Syndrome Clinical Trials

Assessment of Hypotonia in Children With Down Syndrome

Start date: April 1, 2019
Phase:
Study type: Observational

Hypotonia is a common trait in infants with Down syndrome, resulting in pathologies and delays in gaining basic motor skills. There are no screenings available to aid in early diagnosis, therefore, the purpose of this study is to develop a way to test for hypotonia in children with Down syndrome.

NCT ID: NCT05130931 Completed - Clinical trials for Carpal Tunnel Syndrome

Impact of a Conservative Treatment in the Waiting List for Carpal Tunnel Syndrome Surgery.

Start date: May 12, 2021
Phase: N/A
Study type: Interventional

STC is considered one of the most prevalent peripheral neuropathy of the upper quadrant. Systematic review shows that conservative treatment is effective for treatment of CTS. In Spain, most patients diagnosed by CTS are included in surgery list without considering conservative treatment as first option or providing drugs or night splint . However, surgical treatment is not always necessary for these patients, and waiting list delays can lead to aggravation of patients' symptoms. Researches believe that performing a conservative treatment including diacutaneous fibrolysis on carpal tunnel syndrome patients, could reduce waiting surgery list, reduce the cost-effectiveness rate of the surgical process and improve patient's satisfaction and clinical findings. In addition, patients of any level of severity and with systemic pathology will be included to define which patients would benefit from surgical treatment and which from physiotherapeutic treatment. The aim is to find out the impact of a multimodal physiotherapy treatment in patients with Carpal Tunnel Syndrome (CTS) on the patient and the Aragonese Health System. A randomized controlled clinical trial will be performed. First a pilot study will be carried out. Patients with carpal tunnel syndrome included on waiting surgery list of Miguel Servet Hospital will be recruited. They will be randomized into a control group (staying in waiting list and performing healthcare standard) and into an experimental group (3 sessions of 45 min of diacutaneous fibrolysis and homebased treatment). Different outcomes will be assessed at pre-treatment, at the end of treatment, 3 and 6 months later.

NCT ID: NCT05130736 Recruiting - Clinical trials for Post-Viral Fatigue Syndrome

Rehabilitation Robot in Patients With Post-Coronavirus Disease (COVID-19) Fatigue Syndrome

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to compare the effectiveness of two models of rehabilitation: - traditional neurological rehabilitation, and - neurological rehabilitation combined with a rehabilitation robot (Luna by EGZOTech). An additional goal is to test the qualitative diagnostic reference using the surface electromyogram of the Luna robot (certified as a Medical Device) for functional diagnostics based on standardized clinical tests.

NCT ID: NCT05130450 Active, not recruiting - Clinical trials for Familial Chylomicronemia Syndrome

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS)

Start date: November 18, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effect of olezarsen (formerly known as AKCEA-APOCIII-LRx) on the percent change in fasting triglycerides (TG) from baseline.

NCT ID: NCT05130047 Completed - Clinical trials for Irritable Bowel Syndrome With Diarrhea

Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM)

Start date: December 1, 2021
Phase: Phase 2
Study type: Interventional

This single-center, randomized, double-blind, placebo-controlled study is designed to compare effects of aldafermin, (NGM282), 1 mg, and placebo given daily by subcutaneous injection on bowel functions and hepatic synthesis and fecal excretion of bile acids in patients with diarrhea associated with bile acid malabsorption (BAM).

NCT ID: NCT05129020 Recruiting - Clinical trials for Neonatal Abstinence Syndrome

Neurostimulation to Improve NOWS Outcomes

SPROUT
Start date: July 26, 2022
Phase: N/A
Study type: Interventional

The objective of this study is to determine if tAN therapy can reduce the median number of days of oral morphine administered to an infant after start of treatment.