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Syndrome clinical trials

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NCT ID: NCT05581576 Recruiting - Clinical trials for Restless Legs Syndrome

Pitolisant in Refractory Restless Legs Syndrome

Start date: September 20, 2022
Phase: Phase 4
Study type: Interventional

This is an open-label trial in Restless Legs Syndrome (RLS) patients inadequately treated with standard therapy, defined by an IRLS score greater than 15. Investigators hypothesize that the study drug, Pitolisant (Wakix), may improve RLS symptoms.

NCT ID: NCT05581147 Completed - Hypothyroidism Clinical Trials

Thyroid Function and Structure IN Klinefelter Syndrome

THINKS
Start date: May 11, 2007
Phase:
Study type: Observational

This is a longitudinal retrospective study for the evaluation of thyroid function and structure in patients with Klinefelter syndrome compared to healthy controls and patients affected by chronic lymphocytic thyroiditis.

NCT ID: NCT05579795 Not yet recruiting - Clinical trials for Tethered Cord Syndrome

Surgical Management and Outcome of Tethered Cord Syndrome

Start date: November 2, 2022
Phase:
Study type: Observational

The aim of this study is to assess surgical management and outcome of Tethered cord syndrome

NCT ID: NCT05578963 Enrolling by invitation - Clinical trials for Carpal Tunnel Syndrome

Correlation Between Palmaris Longus Muscle and Carpel Tunnel Syndrome

Start date: October 15, 2022
Phase:
Study type: Observational

The Palmaris longus (PL) muscle is a long, adaptable muscle that lies between the Flexor Carpi Ulnaris and Flexor Carpi Radialis muscles in the shallow volar segment of the lower arm. It has been acknowledged as a minimal muscle, nonetheless, in light of the fact that reviews have uncovered that around 30% of the populace might be feeling the loss of this muscle in one lower arm (one-sided) or the two lower arms (reciprocal), but the rate could continuously fluctuate. Carpal tunnel syndrome is an often-observed disease that causes pain, numbness, and tingling in the hand and arm. The disease occurs when one of the major nerves to the hand - the median nerve - is compressed as it moves across the wrist. The abnormal passage of palmaris longus tendon through the carpal tunnel leads to a contributory factor for causing the median nerve compression.

NCT ID: NCT05578469 Active, not recruiting - Marfan Syndrome Clinical Trials

Surgical Treatment of Marfan Syndrome With Subluxation Lens

Start date: January 1, 2016
Phase:
Study type: Observational

To analyze the postoperative visual effects, and to compare the safety and efficacy of different surgical treatment with of Marfan Syndrome with subluxation lens.

NCT ID: NCT05578105 Recruiting - Clinical trials for Autoimmune Polyendocrine Syndrome Type II

Prevalence and Genetic Alternation of Autoimmune Polyglandular Syndrome Type II in Taiwan

Start date: January 1, 2022
Phase:
Study type: Observational

Autoimmune polyendocrine syndrome (APS) is an autoimmune disease involving at least two endocrine organ. It is classified into type I and type II diseases. Among them, APS type II is more common. It is diagnosed when two of the three following diseases are diagnosed in the same patient, including type 1 diabetes mellitus, autoimmune thyroid disease, and primary adrenal insufficiency. In this study, we will observe the epidemiology, clinical characteristics, and genetic variants of APS II in Taiwan.

NCT ID: NCT05577949 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Effect of Aerobics on Physical and Mental Health in Polycystic Ovary Syndrome

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Polycystic ovary is one of the most common metabolic and endocrine disorders in women of reproductive age group. The Rotterdam criteria are used internationally for its diagnosis. It has been reported that 57% of these women have at least one mental disorder. There is no health without mental health and it is fundamental to the good health and well-being of an individual. Women with PCOS are at risk of a wide range of significant psychological difficulties including depression, anxiety, eating disorders, sexual disorders, low self-esteem, poor body image, and overall low quality of life. In the healthy population, exercise plays a pivotal role in the optimization of mental health, but there is little evidence available to demonstrate its effects on women with PCOS. So, this study has been designed to study the effects of structured aerobics exercise programs on the mental and physical health of women with PCOS.

NCT ID: NCT05577845 Recruiting - Clinical trials for LARS - Low Anterior Resection Syndrome

5-HT3 Receptor Antagonist (Ramosetron) vs Loperamide for the Treatment of Low Anterior Resection Syndrome(RALARS)

RaLARS
Start date: March 27, 2023
Phase: N/A
Study type: Interventional

Safety & Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) versus Loperamide for the Treatment of Low Anterior Resection Syndrome (RALLARS): Multicenter Randomized Controlled Trial

NCT ID: NCT05577754 Recruiting - Clinical trials for Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)

Assessment of the Efficacy and Safety of Alpelisib (BYL719) in Pediatric and Adult Patients With Megalencephaly-CApillary Malformation Polymicrogyria Syndrome (MCAP)

SESAM
Start date: November 28, 2022
Phase: Phase 2
Study type: Interventional

This study is a two periods multi-center Phase II trial, with a 6 months double-blind, placebo-controlled period followed by open label period, to assess the efficacy and safety of alpelisib (BYL719) in pediatric and adult patients with Megalencephaly-CApillary malformation Polymicrogyria syndrome (MCAP)

NCT ID: NCT05577676 Completed - Clinical trials for Carpal Tunnel Syndrome

Hydrodissection Between Normal Saline and a Combination of Triamcinolone Acetonide, Normal Saline, and Lidocaine in CTS

Start date: September 13, 2022
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to compare the functional outcome of hydrodissection of the median nerve by normal saline only and a combination of triamcinolone acetonide, lidocaine, and normal saline. The main question it aims to answer are: • What is the outcome comparison of ultrasound-guided hydrodissection between normal saline only and combination of triamcinolone acetonide, normal saline, and lidocaine in mild to moderate carpal tunnel syndrome? Participants diagnosed with mild or moderate CTS will be randomly assigned to two groups and be hydrodissected under ultrasound guidance. Researchers will compare if normal saline gives similar or better functional outcomes than steroids.