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Surveillance clinical trials

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NCT ID: NCT06223347 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Improved and Simplified Staining Technique for Dysplasia Detection in Colitis

IST-DDC
Start date: January 2024
Phase:
Study type: Observational

Comparing chromoendoscopy to a digital staining technique and White light in patients with IBD attending scheduled surveillance colonoscopy

NCT ID: NCT06039917 Not yet recruiting - Clinical trials for Artificial Intelligence

Effect of the Automatic Surveillance System on Surveillance Rate of Patients With Gastric Premalignant Lesions

Start date: September 10, 2023
Phase: N/A
Study type: Interventional

In this study, we proposed a prospective study about the effect of the automatic surveillance system on surveillance rate of patients with gastric premalignant lesions. The enrolled patients were divided into group A with intelligent surveillance system, group B with manual reminder, and group C with natural state. The surveillance among the three groups will be compared.

NCT ID: NCT05942456 Recruiting - Osteosarcoma Clinical Trials

Soluble B7-H3 as a Biomarker for Osteosarcoma

Start date: June 5, 2023
Phase:
Study type: Observational

Increasing data has indicated an association between increased soluble B7-H3 (sB7-H3) levels and unfavorable prognosis in patients with malignancies. However, the level of sB7-H3 and its clinical significance in osteosarcoma are not well known. In this present study, we investigated whether sB7-H3 levels in serum could be as a biomarker for osteosarcoma treatment.

NCT ID: NCT05894850 Not yet recruiting - Clinical trials for Artificial Intelligence

Effect of the Automatic Surveillance System on Surveillance Rate of Colorectal Postpolypectomy Patients

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

In this study, we proposed a prospective study about the effect of the automatic surveillance system on surveillance rate of colorectal postpolypectomy patients. The enrolled patients were divided into group A with intelligent surveillance system reminding though telephone and message, group B with intelligent surveillance system reminding though message, group C with manual reminder, and group D with natural state. The surveillance among the four groups were compared.

NCT ID: NCT05751824 Not yet recruiting - Clinical trials for Artificial Intelligence

Evaluating the Effect of the Automatic Surveillance System on Surveillance Rate of Colorectal Postpolypectomy Patients

Start date: February 26, 2023
Phase: N/A
Study type: Interventional

In this study, we proposed a prospective study about the effect of the automatic surveillance system on surveillance rate of colorectal postpolypectomy patients. The enrolled patients were divided into group A with intelligent surveillance system, group B with manual reminder, and group C with natural state. The surveillance among the three groups were compared.

NCT ID: NCT04414956 Recruiting - Clinical trials for Hepatocellular Carcinoma

Combining Biomarkers (AFP, AFP-L3, and PIVKA-II) and Image Tools for Early Detection of Hepatocellular Carcinoma

Start date: July 1, 2016
Phase: N/A
Study type: Interventional

In this study, three biomarkers tests (AFP, AFP-L3 and PIVKA-II) and abdominal sonography or CT scans are performed every 6 months to detect hepatocellular carcinoma (HCC) early in patients with cirrhosis, a high-risk group of HCC. The aim of this study is to confirm the early HCC diagnosis rate in patients with cirrhosis and compare the detection efficacy between tests.

NCT ID: NCT03737539 Recruiting - Colorectal Cancer Clinical Trials

Dynamic Monitoring of ctDNA Methylation to Predict Relapse in Colorectal Cancer After Radical Resection (POSTCA)

Start date: September 1, 2018
Phase:
Study type: Observational [Patient Registry]

This is a prospective, multicenter, observational, single-blinded controlled study. Dynamic monitoring of patients with resectable colorectal cancer was performed using the previously established colorectal tumor-specific plasma ctDNA methylation markers (Multigene methylation detection). Dynamic monitoring of plasma ctDNA methylation before and after treatment and at regular follow-up in patients with colorectal cancer after radical resection of tumor, to explore the predictive effect of postoperative plasma ctDNA methylation on postoperative recurrence and whether dynamic monitoring of postoperative ctDNA methylation could be earlier than imaging examination to indicate tumor recurrence.

NCT ID: NCT03543865 Recruiting - Depressive Symptoms Clinical Trials

Southwest Hub for American Indian Youth Suicide Prevention Research

Start date: March 25, 2019
Phase: N/A
Study type: Interventional

1. To use a SMART design to evaluate which of four sequences of New Hope (NH), Elders Resilience (ER) and Case Management (CM) have the greater effects on immediate and longer-term suicidal ideation (primary outcome) and resilience (secondary outcome) among American Indian (AI) adolescents ages 10-24 identified at risk for suicide. Hypotheses: i. New Hope vs. CM alone will significantly reduce participant suicidal ideation. ii. Elders Resilience vs. CM alone will significantly improve participant resilience. iii. New Hope followed by Elders Resilience will have the strongest effects on suicidal ideation and resilience. iv. CM alone will have the weakest effects of all combinations. Secondary Aims: 2. To examine mediators and moderators of treatment effectiveness and sequencing in order to determine which types and sequence of interventions is best suited for which youth. 3. To assess the acceptability, feasibility and capacity for sustainability of the Hub's key intervention components (Surveillance/Case Management, New Hope and Elders' Resilience) from the perspective of multiple stakeholders as they are implemented across different tribes.

NCT ID: NCT03416478 Recruiting - Colorectal Cancer Clinical Trials

The Implication of ctDNA in the Recurrence Surveillance of Stage II and III Colorectal Cancer

Start date: January 2018
Phase: N/A
Study type: Observational

This study is to evaluate circulating tumor DNA (ctDNA) as a predictive and surveillant method for tumor recurrence in stage II and III colorectal cancer (CRC).

NCT ID: NCT02409472 Completed - Colorectal Cancer Clinical Trials

Intensive Versus Minimal Surveillance of Patients With Resected Dukes B2-C Colorectal Carcinoma

GILDA
Start date: April 1998
Phase: N/A
Study type: Interventional

Dukes B2-C colorectal cancer patients who had no evidence of disease at the end of their front line treatment (surgery and adjuvant radio-chemotherapy, if indicated) are eligible for the trial and randomized to two different surveillance programs. These programs differ greatly in the frequency of diagnostic imaging. They have similar schedules of physical examinations and carcinoembryonic antigen (CEA) assessments. Patients will receive baseline and yearly health-related quality of life (HR-QoL) questionnaires. Primary outcomes are overall survival and QoL.