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Supplementation clinical trials

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NCT ID: NCT06390670 Completed - Clinical trials for Exercise Performance

The Effect of Colostrum Bovinum Supplementation in Endurance Athletes

Start date: March 30, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study was to verify the effect of chronic 12-week high-dose Colostrum Bovinum (COL) and placebo (PLA) supplementation on immunological, hematological and biochemical markers, as well as physical capacity and discipline-specific exercise performance in endurance athletes, in a randomized, double-blind, placebo-controlled crossover trial.

NCT ID: NCT06327646 Not yet recruiting - Pregnancy Related Clinical Trials

Maternal Adherence to MMS in Nepal

NAMASTE MMS
Start date: April 20, 2024
Phase: N/A
Study type: Interventional

Although clinical studies highlight the value of MMS for pregnant and lactating women, implementation research studies are necessary to understand adherence and acceptability to the product and to uncover potential obstacles to implementation in specific contexts. For Nepal, it is crucial to establish whether adherence to MMS supplementation is non-inferior to the existing IFA supplementation for 180 tablets, which has a high (65%) adherence rate. It is also important to investigate how whether providing MMS in bottles (containing a substantial quantity, such as 90 count bottles twice during pregnancy) might impact ANC utilization, particularly in terms of ensuring that pregnant women attend at least eight ANC visits. Furthermore, assessment of MMS acceptability, including pill taste, smell, size, swallowability, side effects, benefits as well as aspects such as product labeling and packaging, among end users in Nepal, is needed to understand acceptability of MMS vs. IFA. Finally, implementation issues within the health system, including the need of trainings for healthcare workers' and, female community health volunteers (FCHVs)' training needs; and government stakeholders' interest and barriers;; community s Social and behavioral change communication needs, and issues around supply chain issues should be well-understood and documented to inform prior to scale-up to support a smooth transition of MMS. Thus, Helen Keller International, in collaboration with Nepal's Ministry of Health and Population (MoHP) and the Eleanor Crook Foundation (ECF), will conduct a set of four mixed-methods studies to generate evidence and insights that inform the development of an MMS supplementation strategy. This trial in one province of Nepal is the first study that will be complemented by one additional quantitative study and two qualitative studies to generate evidence on the topics mentioned.

NCT ID: NCT05878106 Recruiting - Breast Cancer Clinical Trials

Creatine Supplementation and Resistance Training in Patients With Breast Cancer

CaRTiC
Start date: April 8, 2024
Phase: N/A
Study type: Interventional

Background: Creatine supplementation is an effective ergogenic nutrient for athletes, as well as people for people starting a health or fitness program. Resistance training previously been identified as an important method of increasing muscle mass and strength among people, specially in people with cancer to avoid sarcopenia. The potential of creatine supplementation for adaptations produced by strength training in cancer patients are still unknown. Objective: the primary aim of this study is to evaluate the effectiveness of a 16-week supervised resistance training program intervention with and without creatine supplementation in patients with breast cancer. Methods: A multicentre, randomized, double-blind, placebo-controlled study designed to evaluate the effects of creatine supplementation in addition to resistance training in breast cancer patients. Patients will be randomly assigned to 3 groups: a control group (CG) and two experimental groups. The first resistance training group (RG) will perform resistance training, while the second resistance-creatine experimental group (RCG) will perform the same resistance training as the RG and will also receive a 5 g/day supplementation of creatine for the duration of the exercise the 16-week intervention. RG participants will follow the same daily dosing protocol, but in their case, with dextrose/maltodextrin. Resistance training will be a 16-week supervised workout that will consist of a series of resistance exercises (leg press, knee extension, knee bends, chest press, sit-ups, back extensions, pull-ups, and shoulder press) that involved the largest muscle groups of the body and will be performed three times a week on non-consecutive days. Both the RG and the RCG will receive a supplement of soluble protein powder (20-30 g) daily. Discussion: The results of this intervention will help to better understand the potential of non-pharmacological treatment for improving strength and wellbeing values in breast cancer patients with and without creatine supplementation.

NCT ID: NCT05750342 Completed - Obesity Clinical Trials

Clinical Trial to Analyze the Efficacy of a Supplement Extracted From Persimmon on Overweight / Obesity.

PERSOB
Start date: February 1, 2023
Phase: N/A
Study type: Interventional

Randomized, controlled, double-blind clinical trial, with two parallel branches depending on the product consumed (experimental product and placebo product) and single-center, to measure the efficacy of a supplement extracted from Persimmon on overweight and obesity grade I in subjects with BMI over 25.

NCT ID: NCT05597189 Completed - Back Pain Clinical Trials

Clinical Study for Palliative/Preventive Treatment of Chronic Back Pain

Backin
Start date: September 26, 2022
Phase: N/A
Study type: Interventional

Randomized, controlled, double-blind, double-blind clinical trial, with three parallel arms depending on the product consumed (experimental product dose 1 and dose 2 and placebo product) and single-center, to measure the efficacy of a botanical supplement on the prevention of non-joint pain.

NCT ID: NCT05525871 Completed - Supplementation Clinical Trials

Effects of Nitrates and Citrulline Malate on Performance in Professional Professional Soccer

NiCiFut
Start date: August 15, 2022
Phase: N/A
Study type: Interventional

Randomized, single-center, parallel, team-stratified, stratified experimental study to evaluate the efficacy of a high sports supplement in improving high-intensity intermittent exercise performance in professional female soccer players.

NCT ID: NCT05516212 Recruiting - Supplementation Clinical Trials

Caffeine Kinetics and CrossFit®-Specific Performance

Start date: June 29, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The study aims at assessing the relation between caffeine (CAF) and paraxanthine (PAX) kinetics after acute ingestion of caffeine (3 mg/kg body mass) in the form or mono- or multi-ingredient preparations and CrossFit®-specific performance or selected indicators of psychophysiological state. Blood indicators of muscle damage/recovery, acid-base balance and electrolytes levels will be evaluated. The impact of genetic variations in the polymorphisms rs5751876 in ADORA2A gene and rs762551 in CYP1A2 on CAF/PAX kinetics will be considered.

NCT ID: NCT05444959 Recruiting - Supplementation Clinical Trials

The Impact of Exercise / Stress Stimuli on HMB Supplementation Efficacy

Start date: September 10, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The study aims at assessing the influence of β-hydroxy-β-methylbutyrate (HMB) free acid supplementation (90 mg/kg of fat free body mass/day) supplemented for 21 days on protein kinases activity and selected hormones levels, and subsequent improvements in muscle protein synthesis, lean body mass content and aerobic capacity.

NCT ID: NCT04549610 Recruiting - Muscle Damage Clinical Trials

HMB and Exercise-induced Muscle Damage

Start date: November 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

The study aims at assessing the influence of β-hydroxy-β-methylbutyrate (HMB) supplementation (4.0 g/day) supplemented for 7 days in a group of speed-strength trained individuals on lower-body strength performance, selected muscle histological, molecular and blood markers of muscle recovery in response to resistance exercise-induced muscle damage.

NCT ID: NCT04427319 Completed - Supplementation Clinical Trials

The Efficacy β-Alanine Supplementation in Performance Outcomes of Road Professional Endurance Cyclists

ELITE
Start date: February 10, 2020
Phase: N/A
Study type: Interventional

A double-blind, placebo-controlled, randomised, with two arms (product and placebo) unicentric clinical trial to analyse the efficacy on physical performance parameters of a product designed for sport during a lapse of two weeks (7 days).