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Suicide clinical trials

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NCT ID: NCT00601939 Recruiting - Suicide, Attempted Clinical Trials

Effectiveness of Empowerment Group Sessions for Treating Suicidal African American Women in Abusive Relationships

Start date: March 2008
Phase: N/A
Study type: Interventional

This study will evaluate the effectiveness of culturally competent psychoeducational empowerment sessions in treating suicidal African-American women who are in abusive relationships.

NCT ID: NCT00589641 Completed - Depression Clinical Trials

Relapse Prevention for Suicidal Dually Diagnosed Youths

CBT-RP
Start date: July 2005
Phase: Phase 1
Study type: Interventional

The purpose of this study is to develop, refine, and pilot test an augmenting cognitive behavior relapse prevention intervention (CBT-RP) for suicidal, depressed, and alcohol/substance abusing adolescents. No hypotheses are being tested, but it is expected that CBT-RP in addition to treatment as usual will result in improved outcomes relative to treatment as usual alone.

NCT ID: NCT00575575 Completed - Suicide Clinical Trials

Research on Suicidal Ideation of University Students in Harbin City and Cognitive Behavior Therapy

Start date: June 2007
Phase: N/A
Study type: Interventional

The purposes of this research are: - to understand the status of suicidal ideation, suicidal behavior, and depression in Harbin University students; and - to analyse the infect factors of suicidal ideation and suicidal behavior. With cognitive behavior interventions on students with suicidal ideation, suicidal behavior, and middle or high degree of depression, the researchers can provide a scientific and effective intervention to the students. Cognitive therapy for the prevention of suicide attempts: a randomized controlled trial. Brown GK, Ten Have T, Henriques GR, Xie SX, Hollander JE, Beck AT. Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA. gregbrow@mail.med.upenn.edu JAMA. 2005 Aug 3;294(5):563-70.

NCT ID: NCT00520026 Terminated - Suicide Clinical Trials

Suicide Prevention by Lithium - the Lithium Intervention Study

SUPLI
Start date: January 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the proposed suicide preventive effects of lithium in a randomized controlled trial within a group of individuals with depressive disorders. The hypothesis being tested is that lithium treatment will significantly reduce the risk for another suicide attempt.

NCT ID: NCT00429169 Terminated - Depression Clinical Trials

Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression

Start date: June 2004
Phase: Phase 4
Study type: Interventional

The primary study comparing effectiveness for suicidal ideation and/or behavior of two antidepressant medications in depressed patients who have attempted suicide or are currently experiencing suicidal thoughts has been completed. A secondary study component using functional magnetic resonance imaging (fMRI) to investigate different medication effects on reward processing in the same sample is ongoing.

NCT ID: NCT00400088 Terminated - Clinical trials for Major Depressive Disorder

Lithium Versus Paroxetine in Patients With Major Depression Who Have a Family History of Bipolar Disorder or Suicide

Start date: June 2007
Phase: Phase 3
Study type: Interventional

This study is being done to look at how well people respond to two very different drug treatments for depression. Clinically, people with depression can respond differently to drug treatments for reasons which are not always clear. Some of our own recent research suggests that people with depression who have a family history of bipolar disorder or completed suicide, may react differently to standard antidepressant medications than those without such a family history. Our data shows that family history of completed suicide, as well as the known predictor of family history of bipolar disorder, may help identify a pre-bipolar high risk group i.e. they currently have depression but at some future date will declare a bipolar illness (manic-depression) by virtue of development of a manic episode also. Our research suggests that treatment- emergent symptoms in response to a trial of antidepressant, such as agitation may be strong predictors of future bipolarity and inherently dangerous particularly as they are not ascribed to the antidepressant treatment. Finally, it is possible that this subgroup of those with depressive illness may respond better and more safely to lithium, a mood stabiliser used in known bipolar depression. The objective of this proposal is to investigate response to acute lithium treatment in subjects who meet the diagnostic criteria for major depression, but who are potentially at risk for bipolar disorder, by virtue of family history of bipolarity or completed suicide.

NCT ID: NCT00387855 Completed - Suicide Clinical Trials

An Evaluation of the SOS (Suicide Prevention) Program

Start date: September 2001
Phase: N/A
Study type: Interventional

The purpose of this study was to investigate the impact of the SOS suicide prevention program on help-seeking, attitudes toward depression and suicide, and suicidal behavior among high school students. Current research protocol has extended this evaluation to the Middle School version of SOS.

NCT ID: NCT00386711 Not yet recruiting - Depression Clinical Trials

A Study on Improving Detection and Management of Suicide Risk Among Depressed Patients in Primary Care

Start date: October 2006
Phase: Phase 1
Study type: Interventional

improve detection and management of suicide risk among depressed patients in primary care

NCT ID: NCT00342953 Completed - Breast Cancer Clinical Trials

Study of Health Effects of Cosmetic Breast Augmentation

Start date: January 10, 2003
Phase:
Study type: Observational

This study will examine long-term health effects of cosmetic breast augmentation (enlargement) with silicone gel breast implants. There has been concern for some time about the possible effects of breast implants on the immune system particularly regarding the development of certain connective tissue disorders and on the possibility that implants may interfere with the ability to detect breast cancers. More recently, concerns have been raised regarding the possible cancer-causing effect of the implants themselves. These concerns were heightened by reports that the polyurethane foam coating that envelops the silicone gel in some implants may dissolve and produce a chemical called 2,4,-diamino toluene (TDA), which has been linked to an increased risk of breast and other cancers in rats and mice. To address this issue, this study will gather information from the medical records and a questionnaire survey of approximately 12,000 breast implant patients. The questionnaire will request information on perceived complications of the implants; history of breast examinations and mammograms; frequency of breast self examination; development of diseases (particularly cancers and connective tissue disorders) developed subsequent to the augmentation surgery; potential risk factors for these diseases, such as age at menarche (onset of menstruation), age at first birth, age and type of menopause (natural or due to surgery); history of breast biopsies; immune system and connective tissue disorders; cigarette smoking; alcohol consumption; family medical history, and so forth. To evaluate the results, the information will be compared with the same data on 4,000 women who underwent other plastic surgery procedures, such as rhinoplasty, facelift, liposuction, dermabrasion, eyelifts, and others, from the same practices as the breast augmentation patients. Participants will be recruited for the study from several large reconstructive and plastic surgery practices. Among the breast implant patients, women who have had bilateral breast implants for cosmetic purposes only, and not as breast reconstruction after breast cancer surgery, will be eligible. Women with a history of breast cancer may not participate.

NCT ID: NCT00279682 Completed - Depression Clinical Trials

Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT)

Start date: May 1999
Phase: Phase 4
Study type: Interventional

The purpose of this study was to determine the effect of a primary care intervention on reducing suicidal ideation and depression in older patients.