Clinical Trial Details
— Status: Not yet recruiting
Administrative data
NCT number |
NCT06066164 |
Other study ID # |
Tms in SUD patients |
Secondary ID |
|
Status |
Not yet recruiting |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
December 2023 |
Est. completion date |
October 1, 2024 |
Study information
Verified date |
September 2023 |
Source |
Assiut University |
Contact |
Abdelrahman H Goda |
Phone |
01061236939 |
Email |
Abdelrahmangoda17[@]gmail.com |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
To determine the effect of substance use disorder on cortical excitability using transcranial
magnetic stimulation (TMS) , it's a scientific study
Description:
The numbers for substance use disorders are large, and we need to pay attention to them. Data
from the 2018 National Survey on Drug Use and Health suggest that, over the preceding year,
20.3 million people age 12 or older had substance use disorders, and 14.8 million of these
cases were attributed to alcohol. When considering other substances, the report estimated
that 4.4 million individuals had a marijuana use disorder and that 2 million people suffered
from an opiate use disorder. It is well known that stress is associated with an increase in
the use of alcohol and other substances, and this is particularly relevant today in relation
to the chronic uncertainty and distress associated with the COVID-19 pandemic along with the
traumatic effects of racism and social injustice,Trans-cranial magnetic stimulation (TMS) is
a safe and painless technique for evoking activity in neurons in the human brain through the
intact scalp and skull). Since its introduction in the mid-1980s is used to evaluate the
cortico-spinal tract, cortical motor areas,, map motor and cognitive functions, study neural
networks, and modulate brain function with a potential therapeutic aim, On one hand, the
development of specific stimulation protocols, such as the cortical silent period (CSP) and
paired-pulse paradigms, as well as the emerging concept that motor cortical output is
affected by non-primary motor areas, including the ventral and dorsal premotor cortex,
supplementary motor area, and cingulate cortex, has allowed the use of TMS to explore
inhibitory and excitatory interactions within motor cortical regions in several
neuropsychiatric disorders. Different TMS protocols can be used to study different components
of cortical excitability and provide insight in to the regulation of different
neurotransmitter systems.