Substance-Related Disorders Clinical Trial
Official title:
Mindfulness-Based Relapse Prevention for Methadone Maintenance: A Feasibility Trial
Verified date | March 2019 |
Source | Pacific University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The current study was designed to inform protocol adaptation, and to evaluate the feasibility, acceptability, and preliminary efficacy of a mindfulness-based intervention for methadone maintenance clients. Adults (N=15) were recruited from a methadone clinic to participate in a 6-week mindfulness course. Indices of feasibility, including recruitment, retention, data from focus groups and course satisfaction surveys, supported feasibility of the intervention. Outcome measures were self-report, and included depression, craving, PTSD symptoms, and experiential avoidance, and were assessed at baseline, postcourse, and 1-month follow-up. Data were analyzed using qualitative and quantitative approaches. Mean scores on all primary outcomes changed in the expected direction at both postcourse and 1-month follow-up assessment, although only depression and experiential avoidance reached significance. Results support feasibility and acceptability, and provide preliminary data on outcomes for future trials of mindfulness-based approaches within this client population.
Status | Completed |
Enrollment | 14 |
Est. completion date | June 27, 2015 |
Est. primary completion date | June 27, 2015 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - Clearance from clinic staff - Currently enrolled in a methadone maintenance program - Agree to complete assessment questionnaires and attend treatment sessions - Fluent in English Exclusion Criteria: - Indication of active psychosis - Participation in past mindfulness-based relapse prevention group |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
---|---|
Pacific University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Acceptability - Satisfaction with the Course | Satisfaction with the course will be assessed using the Overall Course Satisfaction Survey, items #1-4 (Bowen, Chawla, & Marlatt, 2010). This is a self-report questionnaire, the first 4 items of which are open-ended questions assessing satisfaction with the course, barriers to learning, and perceived helpfulness. | post course (6 weeks) | |
Primary | Acceptability - Enactment of Learned Skills | Enactment will be assessed using the Overall Course Satisfaction Survey, items #5-7 (Bowen, Chawla, & Marlatt, 2010). This is a self-report questionnaire, the last 3 questions of which are 10-point Likert-type items, and assess importance of skills and likelihood of implementing them into daily life after the course ends. Higher scores indicate higher perceived importance and likelihood. | post course (6 weeks) | |
Secondary | Depression | Depression symptoms will be assessed using the Beck Depression Inventory-II, a 21-item self report measure. Items are summed for a total score ranging from 0-63. A score of 0-13 is considered minimal range, 14-19 is mild, 20-28 is moderate, and 29-63 is severe. | 1 month | |
Secondary | Anxiety | Anxiety symptoms will be assessed using the Beck Anxiety Inventory, a 21-item self report measure. Items are summed for a total score that can range between 0 and 63 points. A total score of 0 - 7 is interpreted as a Minimal anxiety, 8 - 15 as Mild, 16 - 25 as Moderate, and 26 - 63 as Severe. | 1 month | |
Secondary | Craving | Craving for substances will be assessed using the Penn Alcohol Craving Scale, a five-item Likert-scaled measure assessing frequency, intensity, duration, and overall levels of craving, adapted to include both alcohol and drugs. Each question is scaled from 0 to 6. Sum scores range from 0-30, with greater scores indicating higher craving. | 1 month | |
Secondary | Trauma symptoms | PTSD symptoms will be assessed using the Post-Traumatic Stress Disorder Checklist-Civilian (PCL-C), which measures presence and severity of trauma symptoms using 16-item Likert-scaled questionnaire. | 1 month | |
Secondary | Experiential avoidance | The Acceptance and Action Questionnaire (AAQ) is a widely used measure of experiential avoidance and psychological inflexibility consisting of nine Likert-scaled items, answer options ranging from 1 (never true) to 7 (always true). High scores reflect greater experiential avoidance and immobility, while low scores reflect greater acceptance and action. | 1 month |
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