Stroke Clinical Trial
Official title:
Effect of Intensive Cognitive Rehabilitation on Cognitive, Motor, and Language Functional Networks in Subacute Stroke Patient
Verified date | March 2023 |
Source | Samsung Medical Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Altered brain networks, including cognitive, motor, and language networks, are investigated by intensive cognitive rehabilitation in subacute stroke patients.
Status | Withdrawn |
Enrollment | 0 |
Est. completion date | February 28, 2023 |
Est. primary completion date | February 28, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 19 Years to 80 Years |
Eligibility | Inclusion Criteria: - Patients aged 19 to 80 years - Patients with subacute stroke within 2 weeks of onset - First-ever stroke - Supratentorial stroke - Less than 8 SAFE (shoulder abduction, finger extension) points - Less than 35 FMA Upper scores - MEP (motor evoked potential) negative - Not more than 24 K-MMSE (Korean Mini-Mental State Examination) score Exclusion Criteria: - Difficult to communicate due to severe language impairment. - Accompanied by an existing serious neurogenic disease - Existing significant psychiatric disorders such as major schizophrenia, bipolar disorder - If there are difficulties in conducting the research - Any patients who are judged by the investigator to be difficult to participate in this study - Patients with contraindicated MRI scans |
Country | Name | City | State |
---|---|---|---|
Korea, Republic of | Samsung Medical Center | Seoul |
Lead Sponsor | Collaborator |
---|---|
Samsung Medical Center |
Korea, Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Strength of connectivity in brain network obtained from MRI neuroimaging data | Participants' MRI neuroimaging data are acquired at pre- and post-intervention. Brain network can be constructed using MRI neuroimaging data, and strength of connectivity can be calculated in the brain network. Strength of connectivity has a value between -1 and 1. | Change in strength of connectivity after intensive cognitive rehabilitation for 4 weeks |
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