Gingivitis and Periodontitis as a Risk Factor for Stroke

Stroke Clinical Trial

Official title: Gingivitis and Periodontitis as a Risk Factor for Stroke

Status Completed

Clinical Trial Summary

Periodontitis and gingivitis are one of the most infectious diseases in humans. Several studies have been carried out on the dependence of periodontitis and stroke. The aim of this study was to investigate gingivitis and periodontitis as risk factors for stroke in the Pakistani population.

Clinical Trial Description

Epidemiologic studies have shown that cerebrovascular accident (CVA) is the 3rd cause of death in developed countries with 0.8 % prevalence in the whole population. Although, the prevalence rate of stroke is reduced yet is one of the most important health problems in the United State. Periodontitis and gingivitis are the two most infectious man diseases. Today, it is estimated that about 35% of people over 30-year-old in America and 50-55% of people in developing countries are involved with these diseases.

These diseases are due to the practice of chronic bacterial infection and the inflammatory response of the host. The relationship between periodontitis and CVA was first introduced by Mackenzi and Millard in 1963 but the importance of this issue was not understood. Periodontal infection can be a complex multiphase disease by associating this infection with organ systems such as cardiovascular, endocrine, reproductive, and respiratory systems. Nowadays, periodontitis is considered a risk factor for atherosclerosis and thromboembolic disease. ;

Related Conditions & MeSH terms

• Gingivitis
• Periodontitis
• Stroke

• NCT number: NCT05101434
• Study type: Observational [Patient Registry]
• Source: Shaheed Zulfiqar Ali Bhutto Medical University
• Status: Completed
• Start date: January 10, 2021
• Completion date: July 20, 2021