Cognitive Rehabilitation With C8 Sciences

Stroke Clinical Trial

Official title:

Cognitive Rehabilitation for Participants With Stroke or Brain Injury Using C8 Sciences

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02384057
• Other study ID #: NRC-2013-04-036
• Status: Completed
• Phase: N/A
• First received: February 23, 2015
• Last updated: March 5, 2018
• Start date: December 2014
• Est. completion date: October 27, 2017

Study information

• Verified date: March 2018
• Source: National Rehabilitation Center, Seoul, Korea
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

C8 sciences program is a cognitive training program mainly developed for the students, and the effectiveness is well established. The aim of this trial is to assess clinical efficacy of the program for cognitive rehabilitation of the patients with stroke or brain injury.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 31
• Est. completion date: October 27, 2017
• Est. primary completion date: October 27, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Participants with stroke or brain injury

• Cognitive deficits

Exclusion Criteria:

• Uncontrolled medical comorbidities

• Not able to perform outcome measurements

• Aphasia, which hamper communication

• Pre-diagnosed psychological or other neurological disease not relevant to stroke or brain injury

Related Conditions & MeSH terms

• Brain Injuries
• Stroke

Intervention

Other:
• Computerized cognitive training program
1000 minutes of computerized cognitive rehabilitation with C8 sciences program
• Conventional cognitive rehabilitation
Same amount of conventional cognitive rehabilitation

Locations

Country	Name	City	State
Korea, Republic of	National Rehabilitation Center	Seoul

Sponsors (3)

Lead Sponsor	Collaborator
National Rehabilitation Center, Seoul, Korea	Hanyang University, National IT Industry Promotion Agency, Republic of Korea

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change from baseline Cambridge Neuropsychological Test Automated Battery(CANTAB) Spatial working memory at 34 th intervention		Baseline, 34th day from baseline
Primary	Change from baseline CANTAB Rapid Visual information Processing at 34 th intervention		Baseline, 34th day from baseline
Secondary	CANTAB Spatial working memory		Baseline, 34th day from baseline, 64th day from baseline
Secondary	CANTAB Rapid Visual information Processing		Baseline, 34th day from baseline, 64th day from baseline
Secondary	CANTAB Motor control task		Baseline, 34th day from baseline, 64th day from baseline
Secondary	CANTAB Paired Associated Learning		Baseline, 34th day from baseline, 64th day from baseline
Secondary	CANTAB reaction time		Baseline, 34th day from baseline, 64th day from baseline
Secondary	CANTAB Attention Switching Task		Baseline, 34th day from baseline, 64th day from baseline
Secondary	CANTAB Stoking of Cambridge		Baseline, 34th day from baseline, 64th day from baseline
Secondary	CANTAB Emotion Recognition Task		Baseline, 34th day from baseline, 64th day from baseline
Secondary	CANTAB Stop Signal Task		Baseline, 34th day from baseline, 64th day from baseline
Secondary	Geriatric depression scale	Older participants	Baseline, 34th day from baseline
Secondary	Beck depression index		Baseline, 34th day from baseline
Secondary	Korean Mini-Mental State Examination (K-MMSE)		Baseline, 34th day from baseline
Secondary	Korean activities of daily living (K-ADL)		Baseline, 34th day from baseline, 64th day from baseline
Secondary	Korean instrumental activities of daily living (K-IADL)		Baseline, 34th day from baseline, 64th day from baseline
Secondary	clinical dementia rating scale (CDR)		Baseline, 34th day from baseline
Secondary	Stroke impact scale		Baseline, 34th day from baseline
Secondary	Subjective memory complaint questionnaire		Baseline, 34th day from baseline, 64th day from baseline
Secondary	NIH toolbox		Baseline, 17th day from baseline, 34th day from baseline, 64th day from baseline
Secondary	Autobiographical memory		Baseline, 34th day from baseline
Secondary	Trail making test (A/B)		Baseline, 34th day from baseline, 64th day from baseline
Secondary	Trail making test - Black and White		Baseline, 34th day from baseline, 64th day from baseline