Stroke Clinical Trial
Official title:
The Motor Effects of Combined Peripheral Nerve Electrical Stimulation and Action Observation on the Affected Hand in People With Stroke
Verified date | August 2018 |
Source | The Hong Kong Polytechnic University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study aimed to investigate if peripheral nerve stimulation (PNS) paired with action observation (AO) would augment motor training in promoting corticomotor excitability for the paretic hand in people with stroke. Twenty subjects in chronic stage of stroke were exposed to 3 different interventions involving one-hour PNS or sham PNS paired with 30 minutes of AO or sham AO, all followed by 30 minutes of finger abduction training in 3 separate sessions.
Status | Completed |
Enrollment | 20 |
Est. completion date | June 30, 2015 |
Est. primary completion date | June 1, 2015 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 43 Years to 80 Years |
Eligibility |
Inclusion Criteria: - age between 40 and 80 years; - has history of first hemispheric stroke of 6or more months; - presence of electromyographic signals in first dorsal interosseous (FDI) during active abduction of the index finger contralateral to the lesioned hemisphere; - medically stable; - able to comprehend instructions. Exclusion Criteria: - past history of musculoskeletal or neurological impairment in the paretic upper limb; - recurrent stroke; - cognitive impairment (Mini-mental state examination (MMSE) < 24); - visual impairment not correctable by optical lens; - presence of metal in the head region or a cardiac pacemaker as contraindications for TMS (Rossi et al., 2009). |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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The Hong Kong Polytechnic University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Corticomotor excitability evoked by Transcranial magnetic stimulation (TMS) | Corticomotor excitability in terms of the slope of the MEP recruitment curve and peak MEP amplitude captured for the contralateral FDI hand muscle in both hemispheres were assessed. | 90 minutes | |
Secondary | Hand dexterity of paretic hand evaluated with Purdue Pegboard | The score was the total number of pins inserted into the holes with paretic hand in 30 seconds. | 24 hours |
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