Stroke Clinical Trial
Official title:
Effects of Mind-body Exercise on Cardiovascular Functions and Dual-tasking Performance in Chronic Stroke Survivors - a Randomized Controlled Clinical Trial
Verified date | August 2017 |
Source | The Hong Kong Polytechnic University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
People with stroke suffer from different impairments, including the ability to dual-tasking,
increased arterial stiffness, and dysfunction of the autonomic nervous system. The decrement
in dual-tasking performance has been found among stroke survivors, and the deterioration has
been related to increased risk of fall in the population. No coherent result has been
concluded from previous studies investigating the effect of different types of exercise
training on enhancing dual-tasking performance among healthy older adults and stroke
survivors.
Increased arterial stiffness and impaired functioning of the autonomic nervous systems, which
have been associated with increased cardiovascular risk and mortality, are common in stroke
survivors. Studies have been suggesting the beneficial effects of aerobic exercise on both
decreasing arterial stiffness and regulating the autonomic nervous system among healthy older
people. However, only a few studies concerning such topic have been conducted among stroke
survivors, yet the results were inconsistent.
Tai Chi is a Chinese traditional martial art and has been employed as a rehabilitation
exercise in recent decades. Tai Chi practitioners should perform the physical movement and
plan the Tai Chi forms simultaneously. The involvement of cognitive functioning gives Tai Chi
a dual-tasking character. Prior studies demonstrated the beneficial effect of Tai Chi
training on dual-tasking performance in healthy older adults, but would the effect extend to
stroke survivors has not yet been studied.
Also, Tai Chi is considered as a mind-body exercise. It is suggested that one should keep a
relaxed status of mind and breathe gently and slowly. Moreover, Tai Chi is an exercise with
moderate intensity. These features have been found to decrease arterial stiffness and benefit
functioning of the autonomic nervous system. Indeed, studies have been showing Tai Chi
reduces arterial stiffness and improves regulation of the autonomic nervous system among
healthy population. Whether such effect can be observed in stroke survivors is still unknown.
This study aimed at investigating the effects of Tai Chi training on dual-tasking
performance, arterial stiffness, and autonomic system functioning among stroke survivors.
Given the special features of Tai Chi and its advantageous effects on the mentioned
functioning, it is expected that stroke survivors may also benefit from Tai Chi training.
Status | Completed |
Enrollment | 56 |
Est. completion date | December 31, 2016 |
Est. primary completion date | December 31, 2016 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 50 Years and older |
Eligibility |
Inclusion Criteria: - Diagnosed with stroke six or more months previously - Able to perform a stepping down maneuver without any physical assistance - Able to walk unaided for 5m indoor - Able to follow instructions in Cantonese Exclusion Criteria: - Any neurological disease other than stroke - Severe visual or hearing impairment - A score of less than 18 on the Cantonese version of the Mini-Mental Status Examination (MMSE) - Any major surgery or severe musculoskeletal injury during the previous six months |
Country | Name | City | State |
---|---|---|---|
Hong Kong | The Hong Kong Polytechnic University | Hong Kong |
Lead Sponsor | Collaborator |
---|---|
The Hong Kong Polytechnic University |
Hong Kong,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in dual-tasking performance - turning-while-walking | A test combining a turning-while-walking test and an auditory Stroop test | week 0, week 12 | |
Primary | Change in dual-tasking performance - stepping back | A test combining a stepping back test and an auditory Stroop test | week 0, week 12 | |
Primary | Change in dual-tasking performance - stepping down | A test combining a stepping down test and an auditory Stroop test | week 0, week 12 | |
Primary | Change in arterial compliance | Large and small arterial compliance measured non-invasively (HDI/PulsewaveTM CR-2000 Research CardioVascular Profiling System; Hypertension Diagnostics, Inc., Eagan, Minnesota, USA) | week 0, week 12 | |
Secondary | Single turning-while-walking test | A walking test in single-tasking condition | week 0, week 12, and week 16 | |
Secondary | Single stepping back test | Stepping back under single-tasking condition | week 0, week 12, and week 16 | |
Secondary | Single stepping down test | Stepping down under single-tasking condition | week 0, week 12, and week 16 | |
Secondary | Single auditory Stroop test | A cognitive task under single-tasking condition | week 0, week 12, and week 16 | |
Secondary | Heart rate variability | Tested the functioning of the cardiac autonomic nervous system | week 0, week 12, and week 16 |
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