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Stroke, Acute clinical trials

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NCT ID: NCT06262217 Recruiting - Stroke, Acute Clinical Trials

Mobile MRI for Immediate Radiological Acute Cerebral Lesion Evaluation in Stroke

MIRACLES
Start date: November 11, 2023
Phase:
Study type: Observational

This prospective observational study will evaluate the potential value of mobile MRI in patients with suspected or proven acute stroke and Transient Ischemic Attack (TIA), undertaking additional imaging in the emergency department, acute stroke unit, or outpatient settings, and comparing diagnostic accuracy, Diffusion-weighted imaging (DWI) lesion volume and detection of complications (brain swelling or haemorrhagic transformation). Information on ease of use, tolerability and image quality will also be gathered.

NCT ID: NCT06261099 Recruiting - Stroke, Acute Clinical Trials

Telerehabilitation-Based Early Upper Extremity Training in Stroke Patients

Start date: February 8, 2024
Phase: N/A
Study type: Interventional

Telerehabilitation method, which is an alternative to face-to-face rehabilitation practices for stroke patients who need intensive, regular and long-term rehabilitation in the early period, has been popularly used in recent years. Telerehabilitation is a practice in which the patient participates in the treatment via digital media without the need for the patient to come to the clinic.

NCT ID: NCT06233682 Not yet recruiting - Stroke Clinical Trials

The Enriched Environment as an Integrated Tool in the Ward Setting

ENVIRONMENT
Start date: January 2024
Phase: N/A
Study type: Interventional

The goal of this longitudinal interventional study is to integrate the enriched environment (EE) in the context of the Neurology Clinic ward of the General Hospital - University of Padua, by verifying its effectiveness and impact on psychological well-being, functional recovery, activity level, and quality of life in people with stroke.

NCT ID: NCT06218563 Recruiting - Healthy Clinical Trials

Study of Cerebral Activation by fNIRS During Vibration-induced Illusion of Movement in Healthy and Stroke Participants.

VIBRANIRS
Start date: January 10, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the cerebral activation of healthy and stroke participants in 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block. The frequency of the vibration being 80 Hz. Healthy participants: - Right arm, eyes opened - Right arm, eyes closed - Left arm, eyes opened - Left arm, eyes closed Stroke participants: - Deficient side, eyes opened - Deficient side, eyes closed The aim is to compare the subjective sensation of movement score and cerebral activations of healthy/stroke participants depending on the condition.

NCT ID: NCT06216457 Not yet recruiting - Stroke, Acute Clinical Trials

Comparative Observation of MeThinks AI Performance in Angiography and Non-Contrast CT Assessment.

COMPASS
Start date: February 1, 2024
Phase:
Study type: Observational

The goal of this prospective observational study is to assess the effectiveness and performance of Methinks AI stroke imaging software platform in acute Code Stroke patients, and as a comparator to study sites utilizing existing AI imaging stroke platforms. The main question[s] it aims to answer is: • Performance of and outcomes associated with the use of the Methinks AI stroke imaging medical device in real-world clinical practice.

NCT ID: NCT06210633 Recruiting - Stroke, Acute Clinical Trials

Prospective Registry of Endovascular Thrombectomy for eXtra-Large Ischemic Stroke

XL-STROKE
Start date: January 20, 2024
Phase:
Study type: Observational [Patient Registry]

Since 2015, many randomized trials have shown that endovascular thrombectomy improve functional outcomes in acute ischemic stroke patients with large vessel occlusion. Recently, five randomized controlled trials (ANGEL-ASPECT [Endovascular Therapy in Acute Anterior Circulation Large Vessel Occlusive Patients with a Large Infarct Core], LASTE [LArge Stroke Therapy Evaluation], RESCUE-Japan LIMIT [The Recovery by Endovascular Salvage for Cerebral Ultra-Acute Embolism-Japan Large Ischemic Core Trial], SELECT 2 [Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke], and TENSION [The Efficacy and Safety of Thrombectomy in Stroke with extended lesion and extended time window]) demonstrated the efficacy and safety of thrombectomy for large infarct patients (defined as Alberta Stroke Program Early Computed Tomography Score [ASPECTS] ≥3 or infarct core <100ml). Patients with extra-large infarct core (volume greater than 100 mL, ASPECTS score of 2 or less) were excluded from these trials. Therefore, the efficacy of endovascular thrombectomy in patients with extra-large ischemic burden has not been well studied. The XL STROKE registry is aiming to investigate the clinical outcomes and safety of mechanical thrombectomy in acute extra-large ischemic stroke.

NCT ID: NCT06208969 Completed - Malnutrition Clinical Trials

The Effect of Nutrition Counseling on Nutritional Status in Stroke Patients

Start date: March 7, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of intensive nutrition counseling on nutritional status and functional recovery in stroke patients over the age of 65, compared to standard nutrition counseling.

NCT ID: NCT06179173 Recruiting - Stroke, Acute Clinical Trials

Effectiveness of High-intensity Aerobic Interval Training on Impairments and Activity Limitations in the Acute Phase of Stroke in Benin

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

This clinical trial aims to examine the effects of combining HIIT on a semi-recumbent cycle ergometer (HIIT-RCE) with conventional physiotherapy on impairments and activity limitations in early subacute stroke. We hypothesized that HIIT combined with conventional physiotherapy would be more effective than conventional physiotherapy in improving workload capacity.

NCT ID: NCT06170086 Active, not recruiting - Stroke, Acute Clinical Trials

Early Neurological Trajectory and Clinical Outcomes in Brain Acute Ischemic Stroke

Start date: September 1, 2023
Phase:
Study type: Observational

Prospective identification of potential responsible blood vessels, provision of intervention targets, prevention of fatal and disabling cerebrovascular diseases, identification of early END patients, determination of clinical treatment pathways, improvement of efficacy, and improvement of prognosis

NCT ID: NCT06162910 Terminated - Stroke, Acute Clinical Trials

Validation of Aspiration Risk Assessment in Stroke Units

ARAS
Start date: February 1, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to test the validity of a modified Daniels swallow test. The original test serves as reference method, the swallow endoscopy (FEES) as "gold standard". Furthermore, it will be examined whether the modified Daniels test can be performed by nursing staff. As a reference method, the test will be performed by experienced speech therapists and the swallowing endoscopy (FEES) by speech therapists and/or physicians.