Stress Echocardiography Versus Coronary Angiography for Left Main Stenosis Detection

Stenosis Clinical Trial

— ESTRIE-TC  

Official title:

Évaluation de l'Echographie de Stress Par Comparaison à la Coronarographie Comme Outil Non Invasif de détection de la resténose Intra endoprothèse du Tronc Commun

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT01620320
• Other study ID #: projet #10-011
• Status: Withdrawn
• Phase: N/A
• First received: July 16, 2010
• Last updated: June 24, 2013
• Start date: July 2010
• Est. completion date: July 2013

Study information

• Verified date: June 2013
• Source: Université de Sherbrooke
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Health Canada
• Study type: Observational

Clinical Trial Summary

Left main stenosis use to be treated by bypass but with the improvement of angioplasty techniques, an increasing number of patients are submit to left main coronary angioplasty. Consequences of left main intra stent stenosis can be disastrous yet, for the moment, no precise recommendation concerning the follow up of these patients exist. The investigators ought to determine if stress echocardiography can predict left main intra stent stenosis as well (non inferiorly)as control angiography that use to be done.

Description:

All patients of the study will pass coronary angiogram and stress echocardiography (treadmill of dobutamine).

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: July 2013
• Est. primary completion date: July 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patients over 18 years old able to give consent and having had left main angioplasty.

Exclusion Criteria:

• Bypass on the left anterior descending coronary artery or left circumflex (" protected left main ")

• Treating physician judge that angiography need to be done straightaway

• Follow up elsewhere than the CHUS

• Patient refusal

• Pregnant women

• Stress echo contraindication(Severe high blood pressure or malignant arrhythmia)or condition that limits interpretation (Left bundle branch block or pacemaker rhythm)

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Constriction, Pathologic
• Coronary Artery Disease
• Coronary Disease
• Left Main Coronary Artery Disease
• Myocardial Ischemia
• Stenosis

Intervention

Other:
• Stress echocardiography
Patients able to exercise will have a treadmill test + echography; the others will have a dobutamine echography.

Locations

Country	Name	City	State
Canada	Centre Hospitalier Universitaire de Sherbrooke, departement de cardiologie	Sherbrooke	Quebec

Sponsors (1)

Lead Sponsor	Collaborator
Université de Sherbrooke

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlation between stress echocardiography results for the detection of left main prosthesis stenosis with coronary angiogram results.		9 to 12 months after left main angioplasty	No