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Spinal Stenosis Lumbar clinical trials

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NCT ID: NCT06367855 Not yet recruiting - Surgery Clinical Trials

Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF : Double Blinded, Randomized Control Trial

MIS-TLIF
Start date: May 1, 2024
Phase: Phase 4
Study type: Interventional

Researchers are considering Dexamethasone as preemptive medication before minimally invasive spine fusion surgery to minimize postoperative back pain with minimal side effects, aiming to enhance the effectiveness of surgery and improve patient outcomes.

NCT ID: NCT05806593 Recruiting - Clinical trials for Spinal Stenosis Lumbar

Feasibility of a Person-centred Digital Program Targeting Physical Activity in Spinal Stenosis Surgery

GetBack
Start date: April 17, 2023
Phase: N/A
Study type: Interventional

Spinal stenosis is the most common cause of degenerative spinal surgery. The majority do not achieve the global recommendations for health-promoting physical activity before or after surgery. Patients with a low level of physical activity and a high degree of fear of movement are at an increased risk of poorer health outcomes after surgery. Increasing the number of steps per day is a way to increase physical activity, which in long term can lead to health benefits. In addition, a digital format is a way to increase the availability of physiotherapy to strive for equal rehabilitation. The overall purpose of the research project is to improve health outcome and increase the availability of rehabilitation for patients at high risk of negative health outcomes after spinal surgery due to spinal stenosis through Get Back, a person-centered and digital program with a focus on physical activity. Before conducting a large-scale study, the investigators want to conduct a study that aims to investigate and develop the Get Back program regarding content and dose, treatment fidelity as well as feasibility in terms of study procedure, compliance, and acceptability. Approximately thirty patients with lumbar spinal stenosis and an identified risk profile for poorer postoperative outcomes will be recruited from two spine clinics in Sweden. The program involves meeting a physiotherapist digitally (through video call) approximately 1 week before surgery to formulate a person-centered health plan. The health plan is monitored and progressed by the physiotherapist by video until eleven weeks after surgery. The Get Back program includes 5 sessions (1 hour each) which are supplemented with 5 booster sessions (30 minutes) to reinforce the intervention. Get Back is based on three key components that run through all sessions. These are person-centeredness, behavioral medicine techniques to reduce fear of movement and worries about pain, as well as to optimize physical activity. The physiotherapist supports the participant's individual resources and abilities through validated behavioral medicine methods in combination with education/communication/knowledge support and behavior-strengthening tools (which are also used in-between sessions) to achieve the participant's personal goals linked to physical functioning, physical activity, and health. The program will be compared to standard physiotherapy.

NCT ID: NCT05619848 Completed - Clinical trials for Spinal Stenosis Lumbar

Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery

RUILS
Start date: October 25, 2022
Phase: Early Phase 1
Study type: Interventional

To investigate the effect of different degrees of fat infiltration on rocuronium use in lumbar surgery was monitored by trapezius muscle relaxation.

NCT ID: NCT05548608 Completed - Clinical trials for Spinal Stenosis Lumbar

Lumbar Proprioception in Patients With Lumbar Spinal Stenosis

Start date: September 10, 2020
Phase:
Study type: Observational [Patient Registry]

The primary aim of this study was to compare spinal proprioception in patients with Lumbal Spinal Stenosis (LSS) (with or without surgery) and healthy controls. A secondary aim was to investigate the effect of pain at target positions where repositioning error (RE) was assessed and TLF flexibility on spinal proprioception deficiency.This cross-sectional and healthy controlled study was conducted in patients with LSS. Participants will be grouped as: Healthy control (Group I), chronic low back pain due to LSS (Group II) and undergoing surgery due to LSS (Group III). Reposition error (RE), pain at target positions of RE and flexibility of the TLF were assesed with iphone tiltmeter app, VAS and goniometric platform, respectively. Target positions of reposition error were: 30º forward bending and 15º backward bending in sitting and standing.

NCT ID: NCT05297513 Not yet recruiting - Clinical trials for Surgical Site Infection

Efficacy of ActiveMatrix on Spinal SSI Rate

Start date: July 2022
Phase: Phase 4
Study type: Interventional

This clinical trial seeks to provide high level of evidence on the efficacy of ActiveMatrix primarily on spinal surgical site infection rate.

NCT ID: NCT05253326 Recruiting - Clinical trials for Spinal Stenosis Lumbar

The Effect of Progressive Muscle Relaxation Exercises on Pain and Disability After Spinal Surgery

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

This study was planned as a randomized controlled experimental study to determine the effect of progressive muscle relaxation exercises on pain and disability in patients undergoing spinal surgery.

NCT ID: NCT05161130 Completed - Low Back Pain Clinical Trials

Predicting Outcomes After Lumbar Fusion for Degenerative Disease

FUSE-ML
Start date: January 1, 2021
Phase:
Study type: Observational

The aim of the FUSE-ML study is to develop and externally validate a robust ML-based prediction tool based on multicenter data from a range of international centers that will provide individualized risk-benefit profiles tailored to each patient undergoing lumbar spinal fusion for degenerative disease. Data will be collected by a range of international centers.

NCT ID: NCT04492774 Active, not recruiting - Clinical trials for Spinal Stenosis Lumbar

Degenerative Lumbar Stenosis Conservative Treatment

GOLDSTEN
Start date: July 1, 2020
Phase: Phase 4
Study type: Interventional

The trial aims to compare the effectiveness of three methods of conservative treatment of degenerative lumbar spine stenosis (DLSS): GOLDIC autologous serum epidural injections, steroid epidural injections and manual therapy.

NCT ID: NCT04447950 Not yet recruiting - Spondylolisthesis Clinical Trials

Randomized Control Trial of Quadratus Lumborum Block for Lumbar Spine Decompression and Fusion Surgery

Start date: June 2020
Phase: N/A
Study type: Interventional

Lumbar spinal decompression and fusion is a commonly performed procedure fro neural impingement and back pain from a variety of pathologies. The importance of pain control in the postoperative period for spinal surgery has been discussed and proven extensively, with both immediate and delayed reduction in complications and improved clinical results. Quadratus lumborum (QL) block was introduced in 2007 and is performed under ultrasound guidance for perioperative pain management in various surgeries.However, the plane for a posterior QL block can be easily reached during open midline spinal surgery. The investigators hypothesize that the posterior QL block is an effective analgesic tool for lumbar laminectomy surgery, because in lumbar laminectomy the quadratus lumborum is already exposed and is in direct visual contact. For that reason it is imperative to test the benefits of this procedure. This is a double blinded randomized control study to assess the results of intra-operative QL block performed for lumbar decompression and fusion.

NCT ID: NCT04443738 Completed - Clinical trials for Spinal Stenosis Lumbar

Long Term Follow up of Spinal Stenosis Inpatients Treated With Korean Integrative Medicine Treatment.

Start date: June 12, 2020
Phase:
Study type: Observational

The purpose of this study is to reveal the effectiveness and safety of integrative Korean medicine for spinal stenosis by observation inpatients treated with integrative Korean medicine.