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Spinal Stenosis Lumbar clinical trials

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NCT ID: NCT04443738 Completed - Clinical trials for Spinal Stenosis Lumbar

Long Term Follow up of Spinal Stenosis Inpatients Treated With Korean Integrative Medicine Treatment.

Start date: June 12, 2020
Phase:
Study type: Observational

The purpose of this study is to reveal the effectiveness and safety of integrative Korean medicine for spinal stenosis by observation inpatients treated with integrative Korean medicine.

NCT ID: NCT04401735 Recruiting - Clinical trials for Spinal Stenosis Lumbar

Effects and Safety of Epidural PDRN vs. Placebo

Start date: November 1, 2019
Phase: Phase 4
Study type: Interventional

This is a single-center, randomized, double-blind clinical study to assess the clinical application and outcomes with epidural PDRN versus Normal saline injection in patients with spinal stenosis.

NCT ID: NCT04204720 Completed - Clinical trials for Spinal Stenosis Lumbar

A Comparison of Intravascular Injection With Chiba Needle and Whitacre Needle

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

Caudal epidural injection (CEI) is effective for spinal pain. However, intravascular injection may occur during CEI, which can lead to hematoma, neurologic deficit and local anesthetics systemic toxicity. Whitacre type needle has been reported to be effective for reducing intravascular injection during transforaminal epidural injection. In this study, we compared the Chiba needle and Whitacre needle on incidence of intravascular injection during CEI.

NCT ID: NCT04058171 Completed - Low Back Pain Clinical Trials

Validation of a Treadmill Walking Test to Discriminate Neurogenic Claudication From Vascular Claudication

Start date: May 1, 2018
Phase:
Study type: Observational

The first aim of this study was to elaborate and validate a treadmill walking test that would help discriminate between neurogenic claudication from vascular claudication. The second objective of this study is to determine if the treadmill walking test can discriminate spinal stenosis from low back pain with radiating pain in lower limb.

NCT ID: NCT03884283 Completed - Clinical trials for Degenerative Disc Disease

Prospective, Multi-center Study to Assess Posterolateral Fusion Using FIBERGRAFT

Start date: February 19, 2019
Phase: N/A
Study type: Interventional

This is a prospective, non-randomized (single arm), multi-center, post-market clinical study designed to evaluate FIBERGRAFT® BG Matrix mixed with autograft and bone marrow aspirate in up to 150 subjects with degenerative disc disease (DDD) with or without radiculopathy, or spinal stenosis and/or spondylolisthesis requiring a fusion. The patient population will include adult (skeletally mature) men and women undergoing 1 or 2 level fusion in the lumbar spine (L2-S1) who are deemed eligible for the study, characterized by inclusion and exclusion criteria.

NCT ID: NCT03863769 Completed - Clinical trials for Spinal Stenosis Lumbar

Chiropractic Distraction Spinal Manipulation- Lumbar Stenosis Study

Stenosis
Start date: March 14, 2019
Phase:
Study type: Observational

To assess the effect of chiropractic distraction manipulation on postural sway and simple measures of performance in patients with the clinical diagnosis of lumbar spinal stenosis.

NCT ID: NCT03584074 Not yet recruiting - Clinical trials for Spinal Stenosis Lumbar

Clinical Trial of Pregabalin and COX2 in Spinal Stenosis

Start date: July 1, 2018
Phase: Phase 4
Study type: Interventional

Aim of this prospective, single-blind, randomized study was to compare the efficacy of the combination of celecoxib and pregabalin and celecoxib only monotherapy for treatment of chronic low-back pain.

NCT ID: NCT03538093 Completed - Clinical trials for Spinal Stenosis Lumbar

Lumbar Stabilization Exercises in Adult Patients With Lumbar Arthrodesis Surgery

Start date: June 21, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine which type of lumbar stabilization exercise is more effective to improve functionality and reduce pain in patients operated with lumbar arthrodesis, to guide clinical practice in the rehabilitation of these patients.

NCT ID: NCT03495661 Completed - Spinal Stenosis Clinical Trials

Decompression vs Physical Training for the Treatment of Lumbar Spinal Stenosis

UppSten
Start date: May 4, 2018
Phase: N/A
Study type: Interventional

Lumbar spinal stenosis (LSS) is characterized by low back and leg pain, walking disturbances and sometimes instability, impaired balance and numbness of the lower limbs. This condition is caused by degenerative changes in the lumbar spine including bulging discs, osteophytes from the arthritic facet joints and thickened ligamentum flavum which together cause narrowing of the spinal canal and thus affect the lumbar nerve roots. This diagnosis is attracting more and more interest due to the aging population with increasing demands for physical activity. LSS is the most common indication for spinal surgery. The surgical treatment involves relieving the pressure from the nerve structures in the stenotic segments through a posterior approach. In several studies, surgery has been shown to have better results than the conservative treatment. However, methodological difficulties and a large proportion of cross-over in these studies indicate that there is still uncertainty about whether surgery is generally a better option. It has been speculated whether the compression of the nerve roots causes in some patients permanent nerve damage with muscle denervation, while in other cases a reinnervation and recovery of the function may occur. Results from neurography and EMG studies have been shown these modalities to have a possible predictive value for the natural process of LSS. If a neurophysiological examination could be able to predict which patients are able to benefit from surgery, many patients could avoid surgery and the risks involved in it. The aim of this study is primarily to evaluate whether surgery with decompression leads to superior results than the non-surgical treatment with structured physical therapy. The main secondary aim is to investigate by means of Neurography and EMG, whether the degree of neurological affection caused by nerve compression affects the outcome of surgery for LSS.

NCT ID: NCT03321357 Completed - Clinical trials for Degenerative Disc Disease

Retest-reliability and At-home-assessment Feasibility of the 5R-STS

5RSTS-2
Start date: December 8, 2017
Phase:
Study type: Observational

The five-repetition sit-to-stand test has been validated and is used primarily in pulmonary medicine and cardiology, and has recently been shown to be a useful tool for the objective assessment of functional impairment in patients with degenerative diseases of the lumbar spine. The goal of this study is to assess the possibility of supervised and unsupervised at-home-assessment. Validation of at-home-assessment would allow the 5R-STS to be easily used as a follow-up tool in clinical trials, for example.