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Smokers clinical trials

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NCT ID: NCT06123598 Recruiting - Smokers Clinical Trials

Effects of Mental Practice and Therapeutic Exercise in Mild Smokers

Start date: October 30, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the effects who would add mental practice based on action observation to a therapeutic exercise program in young mild smokers. The main question it aims to answer is whether the observation of actions prior to the implementation of a therapeutic exercise program improves the response to it on respiratory, strength and muscle function variables. Participants will be assigned to one of 2 study groups: G1) Therapeutic exercise plus action observation training (n=20) G2) Therapeutic exercise plus sham action observation training (n=20)

NCT ID: NCT06108323 Active, not recruiting - Smokers Clinical Trials

Immediate Effects of Mental Practice and Therapeutic Exercise in Mild Smokers

Start date: October 27, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the effects who would add mental practice based on action observation to a therapeutic exercise program in young mild smokers. The main question it aims to answer is whether the observation of actions prior to the implementation of a therapeutic exercise session improves the response to it on respiratory, strength and muscle function variables. Participants will be assigned to one of 2 study groups: G1) Therapeutic exercise plus action observation training (n=20) G2) Therapeutic exercise plus sham action observation training (n=20)

NCT ID: NCT05758272 Active, not recruiting - Exercise Clinical Trials

Evaluation of a Workplace Smoking Cessation Program in Hong Kong (Phase VI)

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

This study aims to test, by a 2-arm RCT, the effectiveness of an intervention that includes mobile phone-supported simple physical exercise for smoking cessation in workplaces in Hong Kong.

NCT ID: NCT04252781 Not yet recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC)

ICONIC
Start date: February 2020
Phase: N/A
Study type: Interventional

Chronic Obstructive Pulmonary Disease (COPD), , secondary to smoking, is a major public health issue with very high direct and indirect costs. The impact on the health system of undiagnosed patients, up to 70% of patients, is increasingly documented. However, systematic spirometry screening remains controversial among smokers in the absence of data to link the detection of new patients with improved management and clinical events and health goals. More generally, there is little data on the evolution of patients in real life once they have entered the care system. The premise is that with systematic screening in general medicine, it is possible to identify the evolution of newly diagnosed COPD patients, to distinguish the different possible evolutions according to the initial phenotype and the management.

NCT ID: NCT04099225 Completed - Healthy Subjects Clinical Trials

Multiple Breath Washout (MBW) Using Sulfur Hexafluoride Reference Values and Influence of Anthropometric Parameters

Start date: August 2015
Phase:
Study type: Observational

Multiple breath washout (MBW) using Sulphur hexafluoride (SF6) has the potential to reveal ventilation heterogeneity in obstructive lung disease which is frequent in patients with small airway disease. However, it is missed by commonly used tests with reference data being scarce and mostly restricted to younger collectives. We aimed to evaluate the influence of anthropometric parameters on SF6-MBW reference values in pulmonary healthy adults.

NCT ID: NCT03608293 Completed - Biomarkers Clinical Trials

Smoker Extracellular Vesicles Influence on Human Bronchial Epithelial Cells

Aerotox-1
Start date: January 1, 2012
Phase: N/A
Study type: Interventional

Cigarette smoking is a habit that has spread all over the world and is a significant risk factor for many diseases including cardiovascular disease, chronic obstructive pulmonary disease(COPD),asthma and lung cancer. Evaluation and understanding of tobacco health effects are of major interest worldwide and answer to important societal concerns. Identification of new biomarkers of exposure to tobacco smoke potentially implicated in COPD or lung carcinogenesis would allow a better observation of tobacco exposed population, thanks to screening establishment at reversible stages of pathological processes. In this study, we question whether cigarettes smoking alters miRNA profiles of extracellular vesicles (EVs) present in human broncho alveolar lavages (BALs), which could affect surrounding normal bronchial epithelial cells status.

NCT ID: NCT03299634 Not yet recruiting - Smokers Clinical Trials

Oral Mucosal Lesions Among Smokers in an Egyptian Population Study.

Start date: November 1, 2017
Phase: N/A
Study type: Observational

This cross-sectional study will assess the prevalence of oral changes among smokers in an Egyptian cohort (patients attending to the hospital of Faculty of Dentistry - Cairo University), aiming that this study can serve as a baseline for future studies with the goal of finding ways to improve oral health and increase awareness of the hazards of smoking in Egypt

NCT ID: NCT03299595 Completed - Smokers Clinical Trials

Oral Mucosal Lesions Among Smokers in an Egyptian Population.

Start date: November 1, 2017
Phase:
Study type: Observational

This cross-sectional study will assess the prevalence of oral changes among smokers in an Egyptian cohort (patients attending to the hospital of Faculty of Dentistry - Cairo University), aiming that this study can serve as a baseline for future studies with the goal of finding ways to improve oral health and increase awareness of the hazards of smoking in Egypt

NCT ID: NCT03086707 Completed - Smokers Clinical Trials

Prefatory Study to Explore Changes in Nasal Mucociliary Clearance and to Standardize Nasal Scraping Procedure

Start date: January 21, 2017
Phase: N/A
Study type: Interventional

This study intends to evaluate the nasal mucociliary clearance (NMC) by determining the value obtained for saccharin transit time (STT) test over the course of 12 hours following a single cigarette use in adult smokers, to compare it relative to never smokers, and to examine the relationship between plasma nicotine levels and STT value in smokers and never smokers. Safety will also be monitored during the study. The planned maximum study duration for a single study participant from Screening through completion of study will be 33 days.

NCT ID: NCT02354677 Completed - COPD Clinical Trials

Repair, Remodeling and Regeneration of the Bronchial Epithelium of COPD Patients

RRR
Start date: October 17, 2014
Phase: N/A
Study type: Interventional

COPD is characterized by exagerated decline FEV1 related to obstructive non reversible airflow. This could be the consequence of structural changes and inflammatory pattern of the bronchial wall. Lesions could lead to normal but also abnormal remodeling specially in COPD including a decrease in Club cells number and function.There is no treatment actually available targeted to a normal repair of the epithelium. The objective of this work is to identify potential targets for reprograming bronchial epithelial cells I order to achieve a good repair.