Sleeve Gastrectomy Clinical Trial
Official title:
Sleeve Gastrectomy With Uncut Jejunal Bypass (SG-uncut JJB) Verus Sleeve Gastrectomy in Obese Patients, a Prospective Randomized Controlled Study
Among various bariatric procedures, sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) are the most frequently performed procedures worldwide. Though SG provides similar weight loss effect to RYGB in short-term follow-up, its long-term and very long-term weight loss effect was reported to be inferior to RYGB. Weight regain after SG remains the major concern after 2-year follow-up due to gradual loss of appetite suppression and lack of malabsorption function. SG plus procedures have been developed to strengthen the effect of SG on diabetes control. It has been reported that SG plus jejunojejunal bypass (SG - JJB) offered better weight loss than SG and similar weight loss to RYGB. The present study aims to evaluate the efficacy and safety of sleeve gastrectomy plus uncut jejunojejunal bypass (SG - uncut JJB).
Among various bariatric procedures, sleeve gastrectomy (SG) and Roux-en-Y gastric bypass
(RYGB) are the most frequently performed procedures worldwide. Though SG provides similar
weight loss effect to RYGB in short-term follow-up, its long-term and very long-term weight
loss effect was reported to be inferior to RYGB. Weight regain after SG remains the major
concern after 2-year follow-up due to gradual loss of appetite suppression and lack of
malabsorption function. SG plus procedures have been developed to strengthen the effect of SG
on diabetes control. It has been reported that SG plus jejunojejunal bypass (SG - JJB)
offered better weight loss than SG and similar weight loss to RYGB. The present study aims to
evaluate the efficacy and safety of sleeve gastrectomy plus uncut jejunojejunal bypass (SG -
uncut JJB).
For SG-JJB procedure, after SG was finished, the jejunum was transected 20-cm distal to Treiz
ligament. After that, another 200-cm jejunum was measured and side-to-side jejunojejunal
anastomosis was made. The anastomotic and mesenteric defects were closed by hand suture.
For SG-uncut JJB procedure, the jejunum was not transected, only 200-cm jejunum 20-cm distal
to Treiz ligament was measured and side-to-side jejunojejunal anastomosis was made. And the
jejunum 3-5cm distal to the anastomosis was ligated with 10# suture.
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