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Sexually Transmitted Diseases clinical trials

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NCT ID: NCT06104813 Completed - Clinical trials for Sexually Transmitted Diseases

Evaluation of Deaf Men's Knowledge About Sexual Health

Start date: September 11, 2023
Phase:
Study type: Observational

Evaluation of Deaf men's knowledge about sexual health in Nancy, France. The study consists of interviews with voluntary deaf men from Nancy, France, in order to assess their knowledge about sexual health, and determine if there is a lack of sexual health awareness. If there is indeed a lack of information about sexual health, the study aims at finding ways of improving the situation, and see how the deaf men would like to have this information delivered to them.

NCT ID: NCT05998499 Completed - HIV-1-infection Clinical Trials

HIV-Infected Latin American Asylum Seekers in Europe: Insights From the EuroLatin HIV Cohort

ELHC
Start date: January 30, 2022
Phase:
Study type: Observational [Patient Registry]

This is a longitudinal observational study conducted in Europe that describes migrants infected with HIV from Latin America who come to Europe with the intention of seeking asylum or international protection. The aim of the study is to identify the barriers this population faces in accessing the healthcare system and to assess disease control

NCT ID: NCT05783856 Completed - Clinical trials for Sexually Transmitted Diseases

Effects of LiveSpo X-secret in Supporting Treatment of Sexually Transmitted Diseases

Start date: May 3, 2020
Phase: N/A
Study type: Interventional

Sexually Transmitted Infections (STIs) are common gynecological infections worldwide, especially in tropical and underdeveloped countries, primarily affecting the reproductive age group. Microbial pathogens causing STIs include bacteria, viruses, fungi, and protozoa. In Vietnam, STIs are a significant public health concern due to their high incidence and tendency to have mild or no symptoms, making them easy to overlook. While antibiotics or antifungal drugs are typically used to treat STIs caused by bacterial or fungal agents such as Chlamydia, Gonorrhea, and Candida, no specific treatment exists for most viral STIs. Thus, vaccination and symptomatic treatment are the primary methods of prevention. The use of broad-spectrum antibiotics can result in side effects such as loss of appetite, fatigue, and sexual problems, while repeated treatments can lead to the emergence of antibiotic resistance, posing a significant challenge for STI treatment worldwide. However, the efficacy of oral or suppository-based probiotics is limited by their slow onset and sensitivity to acidic and temperature conditions. Fortunately, Bacillus strains of probiotics have demonstrated exceptional stability in both acidic and temperature environments, making them particularly well-suited for use as vaginal spray probiotics against STIs. Here, investigators propose that vaginal-spraying probiotics containing Bacillus strains could be a safe and effective symptomatic treatment for STIs caused by viral, fungi, or bacterial pathogens, providing a promising alternative to traditional antibiotic therapy. The aim of the study about to evaluate the effectiveness of vaginal-spraying probiotics containing spores of three strains of Bacillus subtilis, Bacillus clausii, and Bacillus coagulans in preventing and supporting the treatment of vaginal infections. Study Population: sample size is 100. The study is being carried out at Bac Ninh Center for Disease Control. Description of Study Intervention: total of 100 eligible patients are divided randomly into 2 groups (n = 50/group): Patients in the Control group received routine treatment and 3 times/day 0.9% NaCl physiological saline while the patients in the experimental group were treated with LiveSpo X-secret 3 times/day in addition to the same standard of care treatment. The standard treatment regimen is 7 days and is maintained for 28 days. Study duration: 36 months

NCT ID: NCT05763264 Completed - Contraception Clinical Trials

TITLE SAGCS2 Protocol 2.3 + Amend 1

Start date: October 12, 2020
Phase: N/A
Study type: Interventional

The clinical study will compare two lubricated polyurethane male condoms of different thickness with a marketed lubricated control male condom made of natural rubber latex. This crossover study will randomize 300 heterosexual couples to the sequence in which they use five condoms of each of the three study condom types. The clinical failure (breakage and slippage) rates of the two polyurethane condoms will be compared to the clinical failure (breakage and slippage) rate of commercial natural rubber latex control condom using a statistical test of non-inferiority. The study will also compare the acceptability of the two polyurethane condom different thickness with that of the natural rubber latex control condom obtained from interviews and questionnaires with subject couples.

NCT ID: NCT05544851 Completed - Clinical trials for Sexually Transmitted Diseases

The Effect of Education Given to Reproductive Age Women by Teach Back Method on Behaviors

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Sexually transmitted infections (STIs) are an important public health problem as they affect more than 1 million people worldwide every day. The extent of sexually transmitted diseases is still unknown due to underreporting, underdiagnosis or asymptomatic course of these diseases. When the literature is examined, it is seen that the incidence of STD has increased in recent years. The prevalence of premarital sexual intercourse as a result of the decrease in the age of sexual maturity but the increase in the age at marriage in general plays an important role in this increase. It is estimated that 46.8 million of 450 million people in the 15-49 age group living in the European region, including Turkey, have treatable STIs. STD can lead to many serious health problems such as infertility, ectopic pregnancy, cancer, chronic pelvic pain, pelvic adhesions and even death. Moreover, eye diseases, central nervous system infection and death may occur in the baby of an infected mother. In the report of the "Study on Sexual and Reproductive Health in Young People" conducted in Turkey in 2007, it was determined that young people do not have sufficient information about the reproductive organs, structure and physiology, health problems that may arise due to STD, HIV/AIDS, and ways of protection (6).An effective education; can significantly affect the quality of care, personal safety and satisfaction. One of the most effective and successful methods used in education is the Teach-Back method. Tell What You've Learned is a communication and education method used in health education for patients to remember and understand important information about diagnosis, treatment, medications or care. Tell What You've Learned is explained as a method that can be easily used for almost any interaction between healthcare team members and patients and can strengthen team understanding. It is recommended that all personnel, not only clinical caregivers, should use the method effectively in the health care system. It is stated that the conceptual framework of this method is based on the individuals receiving health services to present the information by arranging them according to themselves. It is considered as an effective method in terms of determining whether the transferred information is understood correctly. It is stated that 40-80% of the individuals who consult or immediately forget the information given to them about their health. Various factors that cause communication problems between healthcare professionals and clients during information transfer affect the clarity and permanence of the information given.The "Tell What You Have Learned" method is also expressed as closing the loop, and it is reported to be an effective method when used to eliminate the communication gap between healthcare professionals and service recipients. In addition, it is stated that the use of the method to control the materials (educational brochure, training guide, etc.) used by individuals leaving the hospital to access health information will have a positive effect on health outcomes. From another point of view; It is predicted that it will increase the health literacy rate, and it is accepted as a research-based health literacy intervention that enriches the communication between the health care provider and the service recipient, improves the health outcomes of the individual.

NCT ID: NCT05504954 Completed - Hiv Clinical Trials

A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women: IMARA SA

IMARA-SA pilot
Start date: October 26, 2019
Phase: N/A
Study type: Interventional

Programs which go beyond individual-level behavior change to reduce HIV and STI infections among adolescent girls and young women in sub-Saharan Africa are essential to meet global HIV targets. Informed, Motivated, Aware and Responsible Adolescents and Adults- South Africa (IMARA-SA) is an evidence-based HIV-prevention intervention for adolescent girls and young women (AGYW) and their female caregivers, which has been adapted for a South African audience. This pilot study will assess feasibility in preparation for a randomized controlled trial (RCT). Additionally, the pilot will examine the preliminary effectiveness of IMARA-SA in reducing sexually transmitted infections (STI) and increasing uptake of HIV testing and counseling (HTC) and pre-exposure prophylaxis (PrEP) at follow-up among AGYW. About 60 AGYW-FC dyads will be enrolled and randomized to IMARA-SA or a health-promotion control arm. Following randomization, the dyads will participate in an ~2-day group workshop (~10 hours), which includes joint and separate mother and daughter activities. AGYW and FC will complete baseline assessments and follow-up assessments approximately 6 months later. Assessments will include surveys, STIs testing (for chlamydia and gonorrhea), and uptake of HTC and a 1-month PrEP prescription. Additionally, the intervention's implementation (e.g., acceptability) will be explored.

NCT ID: NCT05370196 Completed - Clinical trials for Sexually Transmitted Diseases

Synthetic Male Condom Slippage-Breakage Study

Start date: June 10, 2022
Phase: N/A
Study type: Interventional

This is a multi-site, double-blind, crossover, randomized phase II study to evaluate the functional performance of a synthetic male condom as compared to a marketed latex condom.

NCT ID: NCT05319613 Completed - HIV Infections Clinical Trials

Reducing Disparities in Rural HIV Prevention

Start date: March 9, 2022
Phase: N/A
Study type: Interventional

HIV and Sexually Transmitted Infection (STI) rates are increasing in rural areas including rural Colorado. Many rural residents find it difficult to access HIV and STI prevention services. In this study, an online survey on HIV and STI Prevention and best practices to provide access to prevention will be administered to rural residents in three zip 3 zones in rural Colorado. In addition to the baseline survey, study participants who are interested and medically eligible may initiate PrEP services with the University of Colorado HIV Prevention Program and receive PrEP through telemedicine visits, mailed home lab kits, and mailed medication. Persistence in PrEP care, acceptability, and feasibility of telemedicine and home lab kits will be measured.

NCT ID: NCT05307991 Completed - HIV Infections Clinical Trials

Integrating Enhanced HIV PrEP Into a STI Clinic in Lilongwe

Start date: March 9, 2022
Phase:
Study type: Observational

This is a prospective cohort study evaluating acceptability, feasibility, and effectiveness of integrating HIV pre-exposure prophylaxis (PrEP) into a sexually transmitted infection (STI) clinic alongside assisted partner notification and etiologic STI testing in Lilongwe, Malawi.

NCT ID: NCT05280834 Completed - Clinical trials for Sexually Transmitted Diseases

Investigation of the Sociodemographic Characteristics and Sexual Health Behaviours of University Students

Start date: December 28, 2019
Phase:
Study type: Observational

The 10-19 age group is defined as the "Adolescent" and the 15-24 age group is defined as the "Youth" by the WHO. Adolescent period is the most vulnerable time to risks in terms of sexual health. Among the sexual health problems experienced by adolescents are sexually transmitted infections(STI), unwanted pregnancies, induced abortions and related complications, not using contraception, STI-induced cancer and infertility, sexual dysfunction.University students are at risk for sexual health because they are in the adolescent age group, they are inexperienced in gaining life experiences, and they are mostly away from the family environment for the first time. Insufficient knowledge in terms of sexual health and insufficient education on sexuality can affect students' attitudes and behaviors related to sexuality. In addition, in developing countries such as Turkey, sexuality is seen as a taboo, and the meanings attributed to sexuality vary according to men and women. In limited studies, it was determined that 24.1% of university student had sexual intercourse at least once, and 40.7% of them had sexual intercourse with more than one person in the last six months. It was determined that 15.5% of the adolescents 60.7% of the youth had sexual experience. In another study with men, it was determined that the students had their first sexual experience at the age of 17-18 on average and 31.0% of them still had active sexual lives. According to the results of a research conducted on first year students of eight universities; It was determined that 19% of the students had sexual experience. These results reveal that one out of every three young people in our country has sexual experience, and that the majority of them are not protected and there is a lack of information about sexuality. It is noteworthy that the rate of becoming sexually active in adolescents and young people is increasing. For this reason, studies are needed to examine the relationship between the status of having a sexual partner and sexual health in university students who have sexual experience. It is important to investigate this relationship and to provide at-risk students with trainings that increase their awareness of sexual health and sexual education. It is planned to examine the relationship between the status of having a sexual partner and sexual health of students studying at Kastamonu University.