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Sentinel Lymph Node clinical trials

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NCT ID: NCT05927818 Recruiting - Ovarian Carcinoma Clinical Trials

Sentinel Lymph Node Biopsy in Early-Stage Ovarian Cancer

Start date: April 15, 2023
Phase: N/A
Study type: Interventional

The primary goal of this prospective study is to define the efficacy of the sentinel lymph node biopsy (SLNB) procedure by comparing it to the results obtained from systematic lymphadenectomy, each performed in participants with a suspicious adnexal mass for early-stage ovarian cancer.

NCT ID: NCT05887921 Completed - Sentinel Lymph Node Clinical Trials

Inguinal Lymphadenectomy for Penile Cancer

Start date: April 30, 2019
Phase: N/A
Study type: Interventional

The aim of the present study is to prospectively compare oncological and functional results of penile radical inguinal lymphadenectomy performed with an open versus videolaparoscopic technique. The main questions it aims to answer are: evaluated the oncological and functional results of inguinal lymphadenectomy performed with minimally invasive techniques using videolaparoscopic instruments vs open inguinal lymphadenectomy according to the standard technique. Participants will undergo treatment of the primary lesion and contextual inguinal lymphadenectomy: - Groin 1: open lymphadenectomy performed by a surgical team with extensive experience in traditional surgery - Groin 2: laparoscopic lymphadenectomy performed by a surgical team with extensive experience in minimally invasive surgery. The results of these procedures will be prospectively collected and compared.

NCT ID: NCT05779982 Completed - Breast Cancer Clinical Trials

SURPASS Retrospective Study

Start date: January 2013
Phase:
Study type: Observational

This study aimed to determine whether sentinel lymph node biopsy (SLNB) could be a reliable option for evaluating nodal status in patients who had responded well to neoadjuvant systemic therapy (NAST), even if they had initially presented with a high nodal burden. The study investigated the outcomes of SLNB followed by axillary lymph node dissection (ALND) in this patient population, taking into account the response to NAST and the breast cancer subtype.

NCT ID: NCT05763641 Recruiting - Breast Cancer Clinical Trials

TAD After Chemotherapy in Locally Advanced Breast Cancer

Start date: February 1, 2021
Phase:
Study type: Observational [Patient Registry]

This is an observational study to validate target axillary dissection (TAD) in locally advanced tumors (cN2 and/or cT4).

NCT ID: NCT05707312 Recruiting - Endometrial Cancer Clinical Trials

Staging Endometrial caNcer Based on molEcular ClAssification

Start date: January 1, 2023
Phase:
Study type: Observational

The SENECA study tries to evaluate the rate of lymph node involvement depending on the molecular subgroup in early-stage endometrial cancer (I/II) patients undergoing surgery as part of their treatment.

NCT ID: NCT05699291 Recruiting - Sentinel Lymph Node Clinical Trials

Cost of Using FLUOrescence to Green of Indocyanine for the Detection of Breast Cancer.

FLUOBREAST-2
Start date: February 23, 2023
Phase:
Study type: Observational

The purpose of this study is to analyze the average direct costs of each of these techniques, represented by the costs directly linked to the management of breast cancer, to the surgical intervention and to the techniques evaluated (Indocyanine Green and isotopes) which are: consultations, hospitalizations, resources consumed during the surgical intervention, as well as the time of the patients, transport...

NCT ID: NCT05663112 Completed - Breast Cancer Clinical Trials

Is Breast Massage Necessary to Find Sentinel Lymph Node?

Start date: December 6, 2021
Phase: N/A
Study type: Interventional

Sentinel lymph node biopsy is important for staging in patients with breast cancer and changes the way of surgery. One of the most commonly used methods to find the sentinel lymph node during surgery is to apply blue dye around the areola and then search for the sentinel lymph node. Breast massage is recommended following administration of the blue dye. However, the necessity of this massage is controversial. In this study, investigators will try to find out whether massage of the breast after blue dye injection has any positive effect on finding the sentinel lymph node.

NCT ID: NCT05623280 Recruiting - Breast Cancer Clinical Trials

Artificial Intelligence Analysis of Fluorescence Image to Intraoperatively Detect Metastatic Sentinel Lymph Node.

Start date: November 1, 2021
Phase:
Study type: Observational

The purpose of this study is to analysis the fluorescence image of the breast sentinel lymph node (SLN) using Indocyanine green (ICG). Moreover, to investigate whether an artificial intelligence protocol was suitable for identifying metastatic status of SLN during the surgery, and evaluate the diagnosis consistency of the AI technique and pathological examinations for lymph node with and without metastasis.

NCT ID: NCT05498051 Completed - Clinical trials for Colorectal Neoplasms

Fluorescent Sentinel Lymph Node Identification in Colon Carcinoma Using Submucosal Bevacizumab-800CW.

IBIZA-1
Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This prospective study aims to assess the safety and feasibility of lymph node identification using bevacizumab-800CW in patients with cT1-3N0-2 tumours, using peritumoral submucosal injections

NCT ID: NCT05497726 Completed - Clinical trials for Colorectal Neoplasms

Fluorescent Sentinel Lymph Node Identification in Colon Carcinoma Using Intravenous Bevacizumab-800CW

IBIZA-2
Start date: January 27, 2023
Phase: N/A
Study type: Interventional

This prospective study aims to assess the safety and feasibility of lymph node identification using bevacizumab-800CW in patients with cT1-3N0-2 tumours, using intravenous administration.