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Sentinel Lymph Node clinical trials

View clinical trials related to Sentinel Lymph Node.

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NCT ID: NCT06130241 Not yet recruiting - Sentinel Lymph Node Clinical Trials

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Initially Node Positive Breast Cancer Patients, Could it Omit Axillary Dissection ?

Start date: November 30, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to determine the accuracy and safety of SLNB after neoadjuvant chemotherapy.

NCT ID: NCT04930692 Not yet recruiting - Breast Neoplasms Clinical Trials

A Prospective Single-center Cohort Study "Preoperative Identification of Sentinel Lymph Nodes Using Contrast-enhanced CT Lymphography in Breast Cancer Patients"

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The main hypothesis of this study is that contrast-enhanced CT lymphography can be used for preoperative visualization of sentinel lymph nodes in breast cancer patients. We assume that CT lymphography is a high-sensitivity and high-specificity method for sentinel lymph nodes' mapping in breast cancer patients. We also assume that positive predictive value and negative predictive value for identification of presence or absence of metastases in sentinel lymph nodes (SLN) will be high enough for preoperative diagnosis of SLN metastases in breast cancer patients. This study will use CT lymphography with periareolar injection of iopamidol and standard protocols of sentinel lymph nodes biopsy using intraoperative indocyanine green (ICG) fluorescence.

NCT ID: NCT04568941 Not yet recruiting - Breast Cancer Clinical Trials

Comparison Study of Different Tumor Biopsy Method for Sentinel Lymph Node Biopsy in Breast Cancer

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

Sentinel lymph node biopsy (SLNB) has become a mainstay surgery method in breast cance, and the identified number of sentinel lymph nodes determines its accuracy for axillary status. Retrospective study indicated that preoperative tumor biopsy results in more detected sentinel lymoh nodes. The clinical trail is designed to compare the effect of three tumor biopsy methods (preoperative vacuum-assisted biopsy, core needle biopsy, and intraoperative excisional biopsy) for sentinel lymph nodes.

NCT ID: NCT04225858 Not yet recruiting - Breast Cancer Clinical Trials

Avoiding Sentinel Lymph Node Biopsy in Breast Cancer Patients After Neoadjuvant Chemotherapy

ASICS
Start date: January 2020
Phase: N/A
Study type: Interventional

This study evaluates whether SLNB can safely be omitted in breast cancer patients with HER2+ or TN tumors who achieve a radiological complete response on MRI after neoadjuvant systemic therapy

NCT ID: NCT03838055 Not yet recruiting - Endometrial Cancer Clinical Trials

Sentinel Node Detection in Endometrial Cancer: A Consolidation Study on Detection Rates of Metastatic Disease

Start date: February 2019
Phase: N/A
Study type: Interventional

Evaluation of removal of Sentinel lymph nodes only for detection of pelvic lymph node metastases in high risk and low risk endometrial cancer.

NCT ID: NCT03549195 Not yet recruiting - Cervical Cancer Clinical Trials

TMTP1 Targeting Micro-metastasis LN in Laparoscopic SLN Detection in Cervical Cancer

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Investigators aimed to determine the validity of the investigator's novel tumor targeted fluorescent peptide TMTP1-ICG to increased accuracy of laparoscopic SLN mapping