Clinical Trials Logo

Clinical Trial Summary

Bright light therapy (BLT) is widely accepted as first-line treatment of seasonal affective disorder (SAD). However, the mechanism of action of BLT is still widely unknown. On the other hand, in mammals, light penetrates the skull bone and reaches the brain, and extra ocular transcranial phototransduction has physiological influences such as changed reproductive cycles and increased brain serotonin levels. Therefore, the investigators run a randomized, placebo controlled, double blind, dose finding study on the putative effect of transcranial bright light in the treatment of SAD.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01293409
Study type Interventional
Source University of Oulu
Contact
Status Completed
Phase N/A
Start date November 2010
Completion date March 2011

See also
  Status Clinical Trial Phase
Completed NCT00502320 - Ramelteon in the Treatment of Sleep and Mood in Patients With Seasonal Affective Disorder Phase 4
Completed NCT00046241 - Prevention of Seasonal Affective Disorder Phase 3
Completed NCT00006517 - Clinical Trials of Three Non-Drug Treatments for Winter Depression (SAD) N/A
Active, not recruiting NCT03691792 - Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy N/A
Completed NCT01462058 - The Role of Vitamin D Supplementation on Well Being and Symptoms of Depression During the Winter Season in Health Service Staff Phase 4
Recruiting NCT01030276 - Bright Light Therapy in Seasonal Affective Disorder (SAD) N/A
Completed NCT01292889 - Study of Genes in Relation to Seasonal Affective Disorder and Major Depressive Disorder N/A
Completed NCT01149135 - Low Intensity 'Blue Light' Treatment of Seasonal Affective Disorder N/A
Completed NCT01048294 - Blue Enriched Versus Standard Light Treatment for Seasonal Affective Disorder(SAD) N/A
Completed NCT02582398 - Influence of Light Exposure on Cerebral MAO-A in Seasonal Affective Disorder and Healthy Controls Measured by PET N/A
Active, not recruiting NCT00269633 - Research Study of Treatment for Winter Depression With Different Colors of Light Phase 2
Completed NCT00076245 - Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD) Phase 1
Completed NCT03313674 - Investigation of Seasonal Variations of Brain Structure and Connectivity in SAD N/A
Completed NCT00016666 - Clinical Trial of Propranolol for Seasonal Affective Disorder Phase 2
Recruiting NCT00114322 - Light-Emitting Diode (LED) Light for Seasonal Affective Disorder (SAD) Treatment N/A
Completed NCT00001485 - Effects of Season on Melatonin Secretion in Healthy Men and Women and Patients With Seasonal Affective Disorder N/A
Completed NCT01462305 - 30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder N/A
Completed NCT00139997 - Environmental Treatment for Seasonal Affective Disorder (SAD) N/A
Completed NCT04251000 - Infrared Photomodulation Therapy for Seasonal Affective Disorder N/A
Completed NCT00809523 - A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD) Phase 2/Phase 3