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Double-Blind Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia

Schizophrenia Clinical Trial

Official title:
A Double-Blind Placebo-Controlled Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia

Clinical Trial Summary

The investigators intend to explore the hypothesis that symptoms of schizophrenia may be reduced by the administration of a probiotic supplement when used in addition to standard antipsychotic medications.

Clinical Trial Description

The primary aim of the current study is:

1. To evaluate the safety and efficacy of a supplemental probiotic therapy, containing the microorganisms Lactobacillus rhamnosus GG and Bifidobacterium lanimalis subsp. lactis (BB12), for individuals with schizophrenia who have residual psychotic symptoms of at least moderate severity.

Secondary aims of the study are:

2. To assess the effect of probiotic treatment on patients' gastrointestinal functioning

3. To study the effect of probiotic treatment in lowering the levels of antibodies to casein and gliadin.

4. To investigate the association between the efficacy of probiotic therapy and initial levels of antibodies to gliadin and casein. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01242371
Study type Interventional
Source Sheppard Pratt Health System
Contact
Status Completed
Phase N/A
Start date August 2010
Completion date August 2012
View Details
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