Artemisinin to Reduce The Symptoms of Schizophrenia

Status Completed

Clinical Trial Summary

The investigators intend to explore the hypothesis that symptoms of schizophrenia may be reduced by the antimalarial compound artemisinin when used in addition to standard antipsychotic medications.

Clinical Trial Description

The aims of the current study are:

1. To evaluate the efficacy and side effects of artemisinin as an add-on compound for patients with schizophrenia who have residual psychotic symptoms of at least moderate severity.

2. To evaluate the effect of artemisinin on cognitive impairments and associated functional skills.

3. To investigate whether treatment with artemisinin produces a significant effect on the levels of antibodies to Toxoplasma.

4. To examine whether changes in cognitive impairment or psychiatric symptoms are correlated with changes in antibodies to Toxoplasma before and during the treatment with artemisinin. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00753506
Study type	Interventional
Source	Sheppard Pratt Health System
Contact
Status	Completed
Phase	N/A
Start date	August 2008
Completion date	May 2010

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