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Theta-burst rTMS in Schizophrenia to Ameliorate Negative and Cognitive Symptoms — tbTMS_SCH21  

Schizophrenia Clinical Trial

Official title:
Theta-burst rTMS in Schizophrenia to Ameliorate Negative and Cognitive Symptoms: a Double-blind, Randomized Clinical Trial

Clinical Trial Summary

The major target of the study is to confirm the safety and efficacy of our augmented protocol of theta-burst TMS in schizophrenia. Our aim is to confirm the beneficial effects of rTMS treatment on multiple aspects of the disorder such as (1) clinical aspect in terms of PANSS, (2) cognitive aspect such as emotion recognition (ER) and working memory (WM) / distractor filtering (DF) performance, and (3) neurobiology in terms of electrophysiology correlates of ER, WM and DF such as event related theta synchronization, resting state theta power, and network connectivity. Response prediction to (theta-burst) TB-rTMS will be the exploratory part of the study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05100888
Study type Interventional
Source Semmelweis University
Contact
Status Enrolling by invitation
Phase N/A
Start date July 11, 2022
Completion date December 1, 2025
View Details
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