Time of Exercise Re-training With Chronic Obstructive Pulmonary Disease (COPD)

Respiratory Diseases Clinical Trial

— CHRONOBIO  

Official title:

Effect of Time of Exercise Re-training on Functional Capacity in Individuals With Chronic Obstructive Pulmonary Disease (COPD)

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06366113
• Other study ID #: 2023-A00363-42
• Status: Recruiting
• Phase: N/A
• Start date: January 2, 2024
• Est. completion date: July 1, 2024

Study information

• Verified date: April 2024
• Source: Clinique de la Mitterie
• Contact: Michaël RACODON, PhD
• Phone: +33320223457
• Email: mracodon[@]clinique-mitterie.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Pulmonary rehabilitation (PR) is an effective intervention for reducing hospital readmissions, secondary events, and mortality in patients with respiratory pathologies.

The program should not be improved by introducing new subjects such as circadian rhythm.

Description:

Respiratory diseases are a leading cause of death in developed countries. To avoid complications and recurrences, secondary prevention in patients with respiratory diseases is essential. Pulmonary rehabilitation (PR) is a well-established and effective treatment that is supervised by medical professionals and conducted in dedicated centres. It has been shown to reduce hospital readmissions, secondary events, and patient mortality.

The timing of reconditioning is crucial. Previous studies have indicated that training times affect strength and power gains. Additionally, the time of day for training can significantly impact progress in aerobic capacity.

Disturbances to the biological clock can have consequences for people with respiratory pathologies, particularly an alteration in muscular function.

Therefore, studying the temporal specificity of exercise re-training in patients with respiratory diseases is of interest.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 90
• Est. completion date: July 1, 2024
• Est. primary completion date: January 2, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• Age = 18 years

• Patient with chronic obstructive pulmonary disease (COPD)

• Registered for respiratory re-education and rehabilitation at the Clinique de la Mitterie

• Number of rehabilitation sessions at least 18 over 4 weeks

• Written informed consent signed by the patient

• Membership of a social security

Exclusion Criteria:

• - cardiovascular contraindications to exercise

• unstable respiratory status (uncompensated respiratory acidosis)

• conditions interfering with the pulmonary rehabilitation process (progressive neuromuscular disease, psychiatric illness)

Related Conditions & MeSH terms

• Lung Diseases
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive
• Respiration Disorders
• Respiratory Diseases
• Respiratory Tract Diseases

Intervention

Other:
• Pulmonary rehabilitation
Pulmonary rehabilitation includes : Exercise re-training with resumption of physical activities therapeutic patient education

Locations

Country	Name	City	State
France	Clinique la Mitterie	Lille

Sponsors (1)

Lead Sponsor	Collaborator
Michaël RACODON

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	6-minute walk test (6MWT)	Walking distance in a test	15 minutes
Secondary	Time limit test (Time-lim)	Endurance exercise holding time in seconds	0 to 900 secondes
Secondary	Sit to stand test (STT)	The number of sit-to-stand repetitions during the test.	1 minute
Secondary	Single arm curl Test (SAC)	The number of bends during the test	1 minute
Secondary	Single-leg stance test (SLT)	The time for balance	1 minute
Secondary	Hospital Anxiety and Depression Scale (HAD)	Hospital Anxiety and Depression score	10 minutes. The maximum mark for each score is 21 and the minimum mark is 0. The higher the score, the more depressed or anxious the person.
Secondary	Pittsburgh Sleep Quality Index	Sleep quality score	10 minutes. The total score ranges from 0 to 21, with 0 indicating no difficulties and 21 indicating major difficulties.