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Renal Insufficiency clinical trials

View clinical trials related to Renal Insufficiency.

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NCT ID: NCT04671771 Recruiting - Kidney Failure Clinical Trials

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access

Start date: December 3, 2020
Phase: N/A
Study type: Interventional

The CSP-2002 study will evaluate the safety and effectiveness of the InnAVasc arteriovenous graft (AVG) when implanted in and used for hemodialysis in participants suffering from end-stage renal failure (ESRD). The InnAVasc AVG is implanted and used similar to other standard-of-care dialysis grafts currently on the market. However, the InnAVasc AVG has been uniquely designed to potentially allow for immediate needle access (same day as implant surgery as opposed to 2-4 weeks of waiting), to potentially reduce excessive bleeding from the graft after dialysis, and it may provide protection from improper or missed needle cannulation attempts.

NCT ID: NCT04660383 Not yet recruiting - Clinical trials for Kidney Failure, Chronic

Intradialytic Inspiratory Muscle Training at Different Intensities and Functional Capacity

Start date: December 2022
Phase: N/A
Study type: Interventional

Investigate the effects of Inspiratory Muscle Training (IMT) performed during hemodialysis (HD) procedures in patients with end stage kidney disease (ESKD). With intervention of thirty-six IMT sessions, performed three times a week, at an intensity of 50%, 30% and 10% (sham) of the maximum inspiratory pressure (MIP).

NCT ID: NCT04656795 Completed - Renal Impairment Clinical Trials

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

Start date: December 2, 2020
Phase: Phase 1
Study type: Interventional

This is an open-label, non randomised, single-dose, study in male and female subjects with renal impairment (severe and if required mild & moderate) compared to male and female subjects with normal renal function.

NCT ID: NCT04655989 Completed - Clinical trials for Chronic Renal Failure

A Study to Demonstrate the Safety and Effectiveness of the NIKKISO DBB-EXA ES Hemodialysis Delivery System

HEMO
Start date: November 30, 2020
Phase: N/A
Study type: Interventional

The study objective is to verify the safety and effectiveness of the DBB-EXA ES Hemodialysis Delivery System to consistently deliver dialysate of the appropriate quality for infusion.

NCT ID: NCT04646889 Completed - Renal Impairment Clinical Trials

Pharmacokinetic Study of AR882 in Subjects With Various Degrees of Renal Impairment

Start date: January 14, 2021
Phase: Phase 1
Study type: Interventional

This is a 2-segment, multi-center, phase 1, open-label, study evaluating the pharmacokinetics and pharmacodynamics of AR882 in subjects with various degrees of renal impairment.

NCT ID: NCT04641650 Completed - Diabetes Clinical Trials

Pilot Study : FreeStyle Libre Pro Flash Continuous Glucose Monitoring System in Subjects With Diabetes on HemoDIALsis

FSL DIAL
Start date: July 21, 2021
Phase:
Study type: Observational

Continuous monitoring of glucose with a FreeStyle Libre pro sensor in diabetic and dialysis patients

NCT ID: NCT04627831 Withdrawn - Clinical trials for Contrast-induced Nephropathy

Comparison of Captisol-Enabled™ Iohexol and Omnipaque™ in Patients With Impaired Renal Function Undergoing Coronary Angiography

Start date: January 2022
Phase: Phase 2
Study type: Interventional

Randomized parallel group study comparing the renal safety of Captisol-Enabled™ Iohexol (CE-Iohexol) Injection and Omnipaque™ (Iohexol) Injection in patients with impaired renal function undergoing coronary angiography.

NCT ID: NCT04626427 Terminated - Clinical trials for Chronic Kidney Diseases

The WavelinQ™ Arterio-Venous Endovascular Fistula: A Global, Post-Market Investigation

WAVE-Global
Start date: December 22, 2020
Phase: N/A
Study type: Interventional

This is a global, multi-center, prospective, post-market, confirmatory, interventional, non-randomized, single-arm clinical investigation evaluating arteriovenous fistula (AVF) creation by means of the WavelinQ™ EndoAVF System in patients who require a vascular access for hemodialysis (HD).

NCT ID: NCT04626167 Recruiting - Clinical trials for Chronic Kidney Diseases

Concomitant Renal and Urinary Bladder Allograft Transplantation

Start date: June 1, 2021
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to establish if concomitant renal and vascularized urinary bladder allograft transplantation is feasible.

NCT ID: NCT04623710 Completed - Healthy Clinical Trials

Study of ALXN2050 in Participants With Renal Impairment

Start date: July 8, 2021
Phase: Phase 1
Study type: Interventional

This study will investigate the impact of impaired renal function on the plasma pharmacokinetics of ALXN2050 in order to provide dosing recommendations for future indications in individuals with impaired renal function.