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Renal Insufficiency, Chronic clinical trials

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NCT ID: NCT02896309 Completed - Clinical trials for Chronic Kidney Disease

The Effect of Correction of Metabolic Acidosis in CKD on Intrarenal RAS Activity

BIC
Start date: September 2016
Phase: N/A
Study type: Interventional

This study evaluates the effect of oral sodium bicarbonate treatment on the intrarenal renin-angiotensin-system in adult patients with a metabolic acidosis and chronic kidney disease. This treatment is compared to sodium chloride treatment, which serves as control for increased sodium-intake and no treatment, which serves as time-control.

NCT ID: NCT02895750 Completed - Clinical trials for Renal Insufficiency, Chronic

Efficacity and Safety of Metformin XR in CKD Stage 1 to 3

METXR/CKD
Start date: August 30, 2017
Phase: Phase 2
Study type: Interventional

There is limited data availability on effect of Metformin XR on 24-h plasma glucose, and there is no available data in chronic kidney disease (CKD). The planned study aims to provide data on glucose plasma level in relation to metformin plasma level in Diabetes Type II patients.

NCT ID: NCT02895425 Recruiting - Clinical trials for End Stage Renal Failure

Registry for End Stage Renal Failure

REIN
Start date: January 2011
Phase: N/A
Study type: Observational [Patient Registry]

The rein registry collects case record data from patients with end stage renal disease followed in French Guiana. This allows to generate incidence and rates for terminal renal disease, mortality rates for each territory. The regional data are pooled in order to get national statistics for end stage renal disease and transplantation activity in order to adapt prevention to the main causes of renal failure and treatment and care infrastructure.

NCT ID: NCT02894164 Completed - Clinical trials for Chronic Kidney Disease

Evaluating the Role of Cystatin C and Creatinine as Markers of Renal Recovery in Critically Ill Patients After Acute Kidney Injury.

Start date: January 2008
Phase: N/A
Study type: Observational [Patient Registry]

This is a cohort study in which patients who survive Acute Kidney Injury (AKI) during intensive care unit (ICU) admission are recalled at 3-6 months and renal function tests are performed. The purpose of the study is describe renal function in AKI survivors at follow-up. Additional aims are to determine how well admission values of renal function markers perform as predictors of renal function at follow-up and whether estimates of renal function at follow-up differ depending on which renal function marker is used.

NCT ID: NCT02892149 Completed - Anemia Clinical Trials

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD)

Start date: August 2016
Phase: Phase 3
Study type: Interventional

A multicenter, randomized, open-label, active-controlled Phase 3 study for the maintenance treatment of anemia in participants with dialysis-dependent chronic kidney disease (DD-CKD)

NCT ID: NCT02890264 Completed - Quality of Life Clinical Trials

Monitoring the Quality of Life of Patients With End-stage Renal Disease (QV-REIN)

Start date: January 2005
Phase: N/A
Study type: Observational

The main purpose for holding this survey is epidemiological surveillance, it must provide the indicators that contribute to the evaluation of the plan "improvement of the quality of life in chronic diseases" and monitoring the goal of 81 health law public in August 2004. This survey is intended to be renewed during the implementation period of the public health law to provide plan monitoring indicators. The main objective is : To describe the quality of life of patients with major end-stage renal disease treated with dialysis method for at least one year. The seconds objectives are : - To contribute to the knowledge of the key determinants of the quality of life among chronic renal failure patients. - To study the influence on way of giving a questionnaire about assessment of level of quality of life

NCT ID: NCT02888171 Completed - Anemia Clinical Trials

Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency

Start date: September 2016
Phase: N/A
Study type: Interventional

The main objective of the study is to compare the impact of oral ferric citrate compared to standard of care oral ferrous sulfate on serum iron, percent transferrin saturation, ferritin, hepcidin and hemoglobin levels in individuals with moderate to severe chronic kidney disease (CKD) and absolute iron deficiency.

NCT ID: NCT02887391 Enrolling by invitation - Clinical trials for End Stage Renal Failure on Dialysis

Comparing Nutritional Status of In-centre Nocturnal Hemodialysis Patients to Conventional Hemodialysis Patients

Start date: January 2016
Phase: N/A
Study type: Observational

Although hemodialysis is life-saving, unfortunately, people on dialysis often have declining health, quality of life as well as poor nutritional status. Hemodialysis patients must follow a very restrictive diet, and many patients do not eat well and usually report poor appetites. A new approach to dialysis is being used in some hospitals in Alberta and elsewhere, called in-centre nocturnal hemodialysis. This in-centre nocturnal dialysis allows people to receive their dialysis at a hospital or clinic while they sleep. Since this in-centre nocturnal dialysis gives people 8-hour hemodialysis treatment 3 times per week (24 hours of dialysis per week) the patients have better removal of the waste products from their bodies than conventional hemodialysis (an average of 12 hours per week). Also of importance, when using in-centre nocturnal dialysis, people will have more time during the day to work, spend with family, as well as have time to shop for food, to cook and even to eat, which in turn will likely result in improvement in the quality of their lives. This study will follow 10 patients on conventional dialysis and 10 patients on in-centre nocturnal dialysis for 6 months and compare their food intake, muscle mass, weight, body mass index (BMI) and nutrition-related lab tests. The purpose of this study is to determine whether there is an improvement in the nutritional status of the in-centre nocturnal hemodialysis patients compared to the nutritional status of conventional hemodialysis patients.

NCT ID: NCT02886975 Recruiting - Clinical trials for Renal Insufficiency, Chronic

Effects of Low Protein Diet in Preventing the Progression of Chronic Kidney Disease(CKD)---a Prospective Study

Start date: August 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether low protein diet and very low protein diet supplemented keto-/amino acid is effective in preventing the progression of chronic kidney disease (CKD , stage 2 to 5).

NCT ID: NCT02885857 Recruiting - Clinical trials for Chronic Kidney Disease

Safety and Efficacy of Shenyankangfu Tablets for Chronic Kidney Disease

Start date: June 2015
Phase: Phase 4
Study type: Interventional

Safety and efficacy of long-term application of Shenyankangfu Tablets in Large sample of patients with chronic kidney disease.