Clinical Trials Logo

Clinical Trial Summary

This study aimed to evaluate influence of melatonin or clonazepam treatment on symptom and polysomnographic parameters in patients with idiopathic REM sleep behavior disorder.


Clinical Trial Description

This study is open-label parallel trial with 4 weeks treatment with slow-release melatonin (Circadin) or with clonazepam (Rivotril). Polysomnography, symptom diary and questionnaire (Clinical Global Impression, RBDQ-HK, PSQI, ESS, SSS, ISI, BDI-II) will be performed before and after 4 weeks of each medications. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03255642
Study type Interventional
Source Kyung Hee University Hospital at Gangdong
Contact
Status Completed
Phase N/A
Start date November 9, 2017
Completion date December 1, 2020

See also
  Status Clinical Trial Phase
Completed NCT03671772 - Progression of Prodromal Markers of α-synucleinopathy Neurodegeneration in the FDRs of Patients With RBD
Recruiting NCT05109364 - Terazosin and Parkinson's Disease Extension Study Phase 2
Recruiting NCT03288909 - Ultra High Field Magnetic Resonance Imaging as a Biomarker for Premotor Parkinson's Disease
Completed NCT04006925 - Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate Phase 4
Completed NCT03353207 - Striatal Dopamine Transmission in Individuals With Isolated Rapid Eye Movement Sleep With Atonia: a Search for Precursor Biomarker for Neurodegeneration
Completed NCT02824341 - Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder N/A
Recruiting NCT03671798 - Establish a National Registry of REM Sleep Behavior Disorder
Enrolling by invitation NCT01453127 - DaTSCAN Imaging in Aging and Neurodegenerative Disease Phase 4
Terminated NCT02871427 - Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder Phase 2
Completed NCT03595475 - Prodromal Markers of First-degree Relatives of Patients With Psychiatric Disorders Comorbid With RBD
Recruiting NCT03660982 - Familial Aggregation and Biomarkers in REM Sleep Behaviour Disorder.
Recruiting NCT05904717 - Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder Phase 2
Not yet recruiting NCT06140511 - DREAMER - IsolateD REM Sleep Without Atonia as a Risk Factor for REM Sleep Behavior disordER
Recruiting NCT04386317 - Terazosin Effect on Cardiac Changes in Early Parkinson's Disease Phase 2
Enrolling by invitation NCT05514106 - MIBG in Aging and Neurologic Disorders Phase 4
Completed NCT03645226 - Gut Microbiota Across Early Stages of Synucleinopathy: From High-risk Relatives, REM Sleep Behavior Disorder to Early Parkinson's Disease
Recruiting NCT05262543 - PREdictive Risk Factors of Conversion Into Idiopathic RBD. Italian Study
Recruiting NCT04071899 - French Validation of a Severity Scale in REM Sleep Behavior Disorder (SEV-TCSP)
Recruiting NCT04048603 - Search for Biomarkers of Neurodegenerative Diseases in Idiopathic REM Sleep Behavior Disorder
Completed NCT02708186 - Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD) Phase 2