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Clinical Trial Summary

This is a phase 1 study to evaluate investigational drug RP-6306 in combination with carboplatin and paclitaxel in patients with TP53 mutated ovarian or uterine cancer. The dose escalation part of the study will determine the maximum tolerated dose (MTD) and recommended Phase 2 Dose (RP2D) and schedule of RP-6306 in combination with carboplatin and paclitaxel and the dose expansion will further assess the safety and tolerability as well as determine the preliminary efficacy of RP-6306 in combination with carboplatin and paclitaxel.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06107868
Study type Interventional
Source University Health Network, Toronto
Contact
Status Active, not recruiting
Phase Phase 1
Start date March 20, 2024
Completion date December 4, 2026

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