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Recurrent Ovarian Cancer clinical trials

View clinical trials related to Recurrent Ovarian Cancer.

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NCT ID: NCT03025867 Approved for marketing - Clinical trials for Recurrent Ovarian Cancer

Expanded Access Protocol for Niraparib in Patients With Recurrent Ovarian Cancer

Start date: n/a
Phase: N/A
Study type: Expanded Access

This is an expanded access program (EAP) for eligible patients with Recurrent Ovarian Cancer. This program is designed to provide access to niraparib prior to approval by the US Food and Drug Administration (FDA). To be eligible, patients with Recurrent Ovarian Cancer following a partial (PR) or complete response (CR) to their most recent platinum-based chemotherapy and must have experienced a PR or CR after the penultimate (next to last) platinum-based chemotherapy for at least 6 months without disease progression after this chemotherapy.

NCT ID: NCT02849353 Recruiting - Clinical trials for Recurrent Ovarian Cancer

Combination of Cryosurgey and NK Immunotherapy for Recurrent Ovarian Cancer

Start date: July 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this study is the safety and efficacy of cryosurgery plus NK immunotherapy to recurrent ovarian cancer.

NCT ID: NCT02788708 Recruiting - Clinical trials for Primary Peritoneal Carcinoma

Lenvatinib and Weekly Paclitaxel for Patients With Recurrent Endometrial or Ovarian Cancer

Start date: May 27, 2016
Phase: Phase 1
Study type: Interventional

This phase I trial studies the side effects and best dose of lenvatinib mesylate when given together with paclitaxel in treating patients with endometrial, ovarian, fallopian tube, or primary peritoneal cancer that has come back or grown. Lenvatinib mesylate may stop the growth of tumor cells by blocking a protein needed for cell growth and may block the growth of new blood vessels necessary for tumor growth. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving lenvatinib mesylate and paclitaxel together may work better in treating patients with endometrial, ovarian, fallopian tube, or primary peritoneal cancer.

NCT ID: NCT02737787 Recruiting - Ovarian Cancer Clinical Trials

A Study of WT1 Vaccine and Nivolumab For Recurrent Ovarian Cancer

Start date: April 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to test the safety of a combination of an investigational WT1 vaccine and another drug called nivolumab. This is the first time that the WT1 vaccine and nivolumab are being used in combination.

NCT ID: NCT02303912 Recruiting - Clinical trials for Recurrent Ovarian Cancer

Safety and Efficacy Study of Nuc-1031 and Carboplatin Combination to Treat Recurrent Ovarian Cancer

ProGem2
Start date: November 2014
Phase: Phase 1
Study type: Interventional

A first in human experimental treatment in which an experimental medicine,Nuc-1031, is used in combination with a standard cancer medicine, carboplatin, to treat ovarian cancer which reappear after standard cancer treatment. The aim of the trial is to determine safety, effectiveness, and clinical activity of this combination treatment.

NCT ID: NCT02195973 Active, not recruiting - Clinical trials for Recurrent Ovarian Cancer

Phase IB Trial of LDE225 and Paclitaxel in Recurrent Ovarian Cancer

Start date: September 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to find out if a new drug, LDE225, is safe and has beneficial effects when combined with paclitaxel in women with platinum resistant ovarian cancer. Platinum resistant ovarian cancer refers to recurrent ovarian cancer that has undergone chemotherapy inclusive of a platinum compound (e.g. carboplatin or cisplatin).

NCT ID: NCT02117817 Withdrawn - Ovarian Cancer Clinical Trials

Phase I BKM120/Abraxane in Solid Tumors, Expansion Phase Recurrent Endometrial or Ovarian Cancer

Start date: February 2015
Phase: Phase 1
Study type: Interventional

The purpose of the first part of this study or the dose escalation portion of the study is to determine what dose of BKM120 and Abraxane is safe to give when the two drugs are used at the same time in patients who are diagnosed with a solid cancer. A solid cancer is a cancer that does not involve the blood, bone marrow or lymph nodes. Dose escalation determines the least toxic and most effect dose of this drug combination for treatment. Once this dose is established, it will be used for the dose expansion phase of the study where we will determine the effect of BKM120 and Abraxane in women diagnosed with a recurrent endometrial or ovarian cancer. We will see whether the combination of both drugs improves the response and survival of patients treated on the two drug regimen. Also we will try to find out whether there are changes in tumors that can help us determine what patients are more likely to respond to BKM120 and Abraxane.

NCT ID: NCT02090582 Active, not recruiting - Palliative Care Clinical Trials

H.O.P.E: Helping Ovarian Cancer Patients Cope

Start date: April 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to test the effect of the gynecologic oncologists with palliative care specialist collaboration (GO-PC) intervention on patient quality of life.

NCT ID: NCT02083536 Withdrawn - Ovarian Cancer Clinical Trials

LDFWART With Docetaxel in Patients With Platinum-Resistant Recurrent Ovarian Carcinoma

Start date: May 2014
Phase: Phase 1
Study type: Interventional

The ultimate clinical aim of this proposed phase I trial is to evaluate the toxicity and determine the recommended phase II dose of combining the effect of LDFWART following administration of docetaxel for 6 cycles in patients with recurrent platinum-resistant ovarian cancer.

NCT ID: NCT02035345 Terminated - Clinical trials for Recurrent Ovarian Cancer

Slowed Carboplatin Infusion for Ovarian Cancer Patients Receiving Carboplatin Re-Treatment

Start date: January 2014
Phase: Phase 4
Study type: Interventional

This is a research study to determine if administering carboplatin at a slower rate when re-treating recurrent ovarian cancer patients prior to the development of a hypersensitivity reaction will decrease the frequency and severity of future hypersensitivity reactions.