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Recurrence clinical trials

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NCT ID: NCT04850131 Completed - Postoperative Pain Clinical Trials

Desarda Repair Compared to Lichtenstein Repair for the Treatment of Inguinal Hernias

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The Lichtenstein technique for hernia repair is safe and simple, but the underlying mesh prosthesis has its setbacks, as it acts as a mechanical barrier5. The mesh does not provide mobile and the physiologically dynamic posterior wall. The most dangerous complication associated with the mesh prosthesis is its migration from the abdominal cavity's primary implantation site. The relatively knew technique developed by Dr. Desarda does not utilize the synthetic mesh rather it uses a strip of external oblique aponeurosis to strengthen the posterior wall. Our study has compared the two methods regarding various aspects.

NCT ID: NCT04849182 Completed - Clinical trials for Benign Paroxysmal Positional Vertigo (BPPV)

Vertistop® D and Vertistop® L in Preventing Recurrence of High-recurrence BPPV

Start date: December 4, 2018
Phase: N/A
Study type: Interventional

Randomized, 3-arm controlled clinical study, to evaluate the effectiveness of supplementation with Vertistop® D (food supplement containing alpha-lipoic acid at modified release, Carnosine and Zinc, Vitamin D and Vitamins B) and Vertistop® L (food supplement containing fast releasing alpha-lipoic acid, Carnosine, Zinc and Curcumin) in preventing recurrence of high-recurrence BPPV (Benign Paroxysmal Positional Vertigo)

NCT ID: NCT04847323 Completed - Relapse Clinical Trials

Clinical Effectiveness of Bonded Versus Vacuum-formed Retainers

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

The purpose of the study was to compare the clinical effectiveness of bonded versus vacuum-formed retainers regarding their retention capacity; periodontal health; survival rates; and patients' perception after 12 months of removal of fixed appliances. The null hypotheses considered that there was no differences between the retainers in relation to the aspects evaluated.

NCT ID: NCT04846257 Completed - Glioblastoma Clinical Trials

Specific Preoperative Dynamic Contrast-enhanced MRI Semi-quantitative Markers Can Correlate With Vascularity in Specific Areas of the Glioblastoma Tissue and Predict Recurrence

Start date: January 1, 2018
Phase:
Study type: Observational

Radiological Markers of vascularity as wash-in rate, washout rate, and capillary time to peak in different single tumour regions were extracted for all glioblastoma patients before being surgically resected from preoperative DCE-MRI. Tissue samples were obtained from different intratumoral regions and peritumoral oedema and evaluated for the vascular endothelial growth factor (VEGF)

NCT ID: NCT04844840 Completed - Keloid Clinical Trials

A Study for Safety and Efficacy Evaluation of Various Doses of STP705 in Reducing Keloid Recurrence

Start date: April 29, 2021
Phase: Phase 2
Study type: Interventional

Phase 2, randomized, double-blind, multiple arm, controlled study to evaluate safety & efficacy of various doses of STP705 in reducing post Keloidectomy keloid recurrence.

NCT ID: NCT04839822 Completed - Clinical trials for Depressive; Episode, Major

Efficacy of Edupression.Com® in Depressive Patients

eFICASY
Start date: April 28, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to investigate the efficacy and adherence of the digital self-help programme edupression.com®.

NCT ID: NCT04838613 Completed - Prostate Cancer Clinical Trials

Study of Diagnostic Performance of [18F]CTT1057 in BCR

GuidePath
Start date: September 30, 2021
Phase: Phase 3
Study type: Interventional

The current study aims at evaluating the diagnostic performance of [18F]CTT1057 as a PET imaging agent for detection and localization of PSMA positivity in patients diagnosed of biochemical recurrence of prostate cancer (PCa), using a composite truth standard. Approximately 190 participants will be enrolled to ensure at least 152 participants are evaluable (i.e. have both an evaluable [18F]CTT1057 PET/CT scan imaging, and at least one evaluable CTS assessment and have not received any prohibited systemic antineoplastic therapy before the completion of PET/CTs and CTS procedures), which will be required for the calculation of the co-primary endpoints.

NCT ID: NCT04835896 Completed - Clinical trials for Recurrent/Metastatic Gastric Cancer

Study of M7824 and Paclitaxel Combination as a Second-line Treatment in Patients With Recurrent/Metastatic Gastric Cancer

Start date: June 2, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Phase 1b/2 study to identify the recommended dose of M7824 for further study with weekly paclitaxel, and to assess the safety and clinical efficacy of this combined treatment in advanced gastric cancer after first line treatment. The study will be conducted in two parts: Part 1 (Phase 1b) dose escalation study to determine the MTD and RP2D of weekly paclitaxel in combination with fixed dose M7824, Part 2 (Phase 2) to further evaluate the safety and tolerability of the combination of M7824 and paclitaxel at the RP2D and determine anti-tumor activity.

NCT ID: NCT04827875 Completed - Keloid Clinical Trials

Safety and Efficacy of AIV001 on Scar Formation and Keloid Recurrence Following Keloidectomy

Start date: June 23, 2021
Phase: Phase 1
Study type: Interventional

To evaluate how safe and effective AIV001 treatment is on scar formation and/or keloid recurrence following keloidectomy.

NCT ID: NCT04799067 Completed - Hemodialysis Clinical Trials

Hyperkalaemia Prevalence, Recurrence and Treatment in Haemodialysis

PRECEDE-K
Start date: May 17, 2021
Phase:
Study type: Observational

The objective of this study is to evaluate the prevalence and recurrence of Hyperkalaemia (HK) in Chinese HD patients and to understand the treatment pattern of HK in China.