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Quality of Life clinical trials

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NCT ID: NCT02460471 Completed - Quality of Life Clinical Trials

Palliative Radiotherapy Protocol in Head and Neck Cancer

Start date: June 2011
Phase: Phase 2
Study type: Interventional

Phase II prospective study or Palliative Radiotherapy of 25 Gy in 5 fractions, Intensity Modulated, for frail patients with incurable head and neck cancer. Comprehensive Quality of life (QLQ-C30, head and neck module, QLQ C15 PAL) and toxicity data (CTCAE v 4.0) collected.

NCT ID: NCT02456506 Active, not recruiting - Quality of Life Clinical Trials

Hyperfractionated Intensity-modulated Radiotherapy (IMRT) Versus Conventional Fraction IMRT for Patients With Loco-regionally Recurrent Nasopharyngeal Carcinoma.

Start date: June 2015
Phase: N/A
Study type: Interventional

This study evaluates the hyperfractionated IMRT in the treatment of patients with locally recurrent nasopharyngeal carcinoma. Half of participants will receive hyperfractionated IMRT, while the other half will receive conventional fraction IMRT.

NCT ID: NCT02455323 Completed - Quality of Life Clinical Trials

The Influence of Manual Therapy in the Quality of Life in Tension-Type Headache

MTheadacheQL
Start date: March 2013
Phase: N/A
Study type: Interventional

The present study aims to assess the quality of life of patients suffering from tension-type headache (TTH) treated for 4 weeks with different manual therapy-based techniques. The study design involved a factorial, randomized, double-blind, controlled study

NCT ID: NCT02453945 Recruiting - Pain Clinical Trials

Use of a Support Bra to Reduce Pain and Improve Surgical Healing in Women Undergoing Sternotomy for Cardiac Surgery

Start date: November 2015
Phase: N/A
Study type: Interventional

The primary purpose of this study is to examine whether a properly fitted support bra on females improves their quality of life post-sternotomy. Specifically, does a support bra reduce discomfort, pain and wound dehiscence.

NCT ID: NCT02444312 Completed - Quality of Life Clinical Trials

Trial of Benefit Finding in Caregivers: The Building Resources in Caregivers (BRiC) Study

BRiC
Start date: June 2015
Phase: N/A
Study type: Interventional

A randomised controlled trial that will compare the effects of a brief benefit -finding writing intervention with an active control condition on quality of life and psychological health among informal caregivers.

NCT ID: NCT02439931 Not yet recruiting - Quality of Life Clinical Trials

Remote Psychosocial Intervention for Brain Tumour Survivors

Start date: July 2015
Phase: N/A
Study type: Interventional

Survivors of high grade brain tumours frequently experience increases in distress, cognitive challenges, and lessened quality of life. At the same time a range of barriers can make it challenging for these individuals to come into the clinic for appropriate psychosocial support. The proposed study is therefore a feasibility study that is designed to develop a manualized, remotely delivered psychosocial intervention for this population and then to test the acceptability, feasibility, apparent efficacy, and areas for improvement of the developed intervention. Further, a remote neuropsychological testing procedure will be developed and implemented and analogous questions will be asked around this procedure.

NCT ID: NCT02432976 Completed - Quality of Life Clinical Trials

Impact of Perioperative Exenatide Infusion on Quality of Life in Cardiac Surgery Patients

ExeQOL
Start date: May 2015
Phase: Phase 2/Phase 3
Study type: Interventional

A diminution of quality of life is often reported by patients after coronary artery bypass graft (CABG) surgery. A part of this diminution could be explain by postoperative left ventricular (LV) dysfunction. Exenatide (Byetta®) is an incretin mimetic, characterized by an anti-hyperglycemic effect that depends on the blood glucose level. Recent data have suggested that exenatide could improve LV function by an inotropic effect in patients suffering from cardiogenic shock or from congestive heart failure. Moreover, patients suffering from congestive heart failure reported a better quality of life when they were treated with exenatide compared to placebo. The investigators hypothesize that perioperative exenatide infusion could improve postoperative quality of life in CABG surgery patients.

NCT ID: NCT02411214 Completed - Cancer Clinical Trials

Decisional Process in Male Fertility Preservation

Start date: January 2013
Phase: N/A
Study type: Observational

The survey analyses how to improve the decision-making process for fertility preservation in the pediatric population based on 1. patient and parent feelings about fertility preservation counselling 2. influence of the emotional state of patients and parents on fertility preservation acceptance 3. support of medical staff and family The study revealed that attention to the fertility preservation pathways was important for the satisfaction of patient's and parent's expectations

NCT ID: NCT02409134 Completed - Quality of Life Clinical Trials

Cognitive Function and Patient-Reported Quality of Life Outcomes Investigation in Patients Taking Vorinostat

Start date: April 2015
Phase:
Study type: Observational

Psychological well-being and cognitive function will be measured in patients enrolled on the primary study, NCT01790568, a phase 2 trial of vorinostat plus tacrolimus and methotrexate to prevent graft versus host disease following unrelated donor hematopoietic stem cell transplantation. Validated questionnaires will be administered to assess patients' level of depression, anxiety, quality of life, perceived cognitive functioning, and sleep quality. Cognitive testing will include reliable and valid measures of processing speed, attention, executive function, episodic memory, and visual learning and memory. The purpose of this study is to determine whether these measures are feasible to administer in patients before and at early time points after bone marrow transplantation .

NCT ID: NCT02395367 Recruiting - Quality of Life Clinical Trials

Prospective, Observational, Real-world Oral Malignant Tumors Study

POROMS
Start date: March 2015
Phase:
Study type: Observational [Patient Registry]

The aim of the study is to construct a register system of oral and maxillofacial malignant tumors based on a prospective, observational, real-world study in north Chinese population.